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  • Scientific papers, books, blog posts. Discussion of whatever you find interesting and notable.

    641 Topics
    4k Posts
    AlphaZanceA
    Abstract Alcoholic beverages produced by fermentation (e.g., beer and wine) are powerful stimulants of gastric acid output and gastrin release in humans. The aim of this study was to separate and specify the gastric acid stimulatory ingredients in alcoholic beverages produced by fermentation. Yeast-fermented glucose was used as a simple model of fermented alcoholic beverages; it was stepwise separated by different methods of liquid chromatography, and each separated solution was tested in human volunteers for its stimulatory action on gastric acid output and gastrin release. Five substances were detected by high-performance liquid chromatography and were analyzed by mass spectrometry and 1H-13C nuclear magnetic resonance spectroscopy. At the end of the separation process of the five identified substances, only the two dicarboxylic acids, maleic acid and succinic acid, had a significant (P < 0.05) stimulatory action on gastric acid output (76% and 70% of fermented glucose, respectively), but not on gastrin release. When given together, they increased gastric acid output by 100% of fermented glucose and by 95% of maximal acid output. We therefore conclude that maleic acid and succinic acid are the powerful stimulants of gastric acid output in fermented glucose and alcoholic beverages produced by fermentation, and that gastrin is not their mediator of action. ... When tested separately, oxalic acid, acetic acid, and L(+)-lactic acid had no stimulatory effect on gastric acid output. Maleic acid and succinic acid, however, significantly increased gastric acid output by 76% and 70%, respectively, of fermented glucose (Figs. 2 and 4). When given together in the concentrations present in beer, maleic acid and succinic acid significantly increased gastric acid output by 95% of MAO(maximal acid output) and 100% of fermented glucose. J. Clin. Invest. 103:707–713 (1999) https://pmc.ncbi.nlm.nih.gov/articles/PMC408116/

  • Websites, newsletters, articles, podcasts, interviews, explainers, books, and other resources that relate to the work of Dr. Raymond Peat.

    62 Topics
    702 Posts
    C
    Cancer Treatments – from Research to Application MCS Foundations for Life, In memory of my dear wife Mihaela Catalina Stanciu https://www.cancertreatmentsresearch.com/ https://jeffreydachmd.com/cancer-articles/

  • Do you have a question? You can post it here, but you will only receive unqualified personal opinions and NOT medical advice in any shape or form. If something seems like medical advice but it's posted in this category, it's actually a personal opinion.

    1k Topics
    10k Posts
    P
    @polba you are welcome It takes time and being consistent But you will feel much better and symptom free Just easy to digest stuff Nothing that irritates your digestion u

  • From medical devices to supplements. Red lights, CO2 tanks, large trash bags, kuinone, and more.

    385 Topics
    4k Posts
    engineerE
    @user73636 if the study you mention is indeed true, it's not clear if it would still be valid for Pyrucet specifically because it includes the ethyl pyruvate to replenish the PDH that the EA would reportedly inhibit.

  • Recipes, food, meal prep, brands. Discuss them all here.

    236 Topics
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    LucHL
    A single portion (240ml) of UHT milk is like welcoming just one tourist in Venice. Not overcrowded. You get the value of the nutrient, but the load is manageable, allowing your small metabolism to process and keep the not-well-fit amino-acid under control (not used). If someone overloads himself with one gallon at a time, twice a day, it won't make you "more nourished." It will make you tired and leave your body feeling crowded and overworked by the demands of processing it all, when something is not well manufactured / recognized. Management is all. Even if you don’t perceive it. And don’t tell you know someone who … Finally: Think, perceive and act, as someone not far from here would say “If UHT milk is the only option, a single portion (~240 ml or half a gallon) is manageable. Think of it like one extra car on a quiet road — the system absorbs it without stress. Moderation keeps the metabolism in control. A moderate amount keeps the metabolism in control of what it can process and discard.

  • Discussing pistol squats, concentric exercise, resting, and other forms of strength training.

    86 Topics
    1k Posts
    R
    @LunaticRed what @alfredoolivas said along with inhibiting cortisol, positive androgenic effects like increased strength, bone growth, anti-anxiolytic, controls blood sugar, controls inflammation from endotoxin. The list goes on. In reality, it is the TRUE male hormone.
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  • cs3000C

    Studies showing cancer reversal / shrinking

    cancer reversal chlorophyll co2
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    MauritioM
    I have ordered a-pinene and phytol from the above website. We'll see if it arrives since the whole process was kind of weird. @cs3000 have you tried supplementing a/b-pinene? It seems to have some interesting properties. Maybe could be used as a cancer prevention. Another possibility: use pinus cembra essential oil. It's ~40% a-pinene and ~10% b-pinene, with other terpenes like limonene making up the rest. Theoretically it should be safe to ingest a drop of the essential oil, if diluted and organic. I haven't tried it yet, but can attest to its calming effects just from inhaling it. In this study it increases life span just from inhaling it in flies under certain conditions. https://www.nature.com/articles/srep28540
  • Mike_FaveM

    Is Vitamin A Deficiency Real?

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    gg12G
    @Mike_Fave Glad to see u on this forum ur a good youtuber
  • T

    Vitamin E Supplement

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    sunsunsunS
    @CurmudgeonApple Bro blocked me?? @sunsunsun please forward this messsage: "I don't care what studies the authors cited or what their subjective opinion is. The objective fact, we know in humans, is that in this subset of patients, prolactin was lowered by 66%. Vitamin E doesn't need to directly interact with the pituarity to exert it's effects. It blocks the production of fatty acid metabolites, and their metabolites, and the encompossing effects of them all. This directly can reduce serotonin/prolactin. So instead of asking the involvement of vitamin E in prolactin, ask your self what do these fatty acid metabolites do? for example; Omega 3 metabolite blocked by vitamin E, increases prolactin https://pubmed.ncbi.nlm.nih.gov/3921344/ "
  • I

    Many water filters are bad for you

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    daposeD
    @Insr just to give you the full rabbit hole… https://www.dancingwithwater.com/ I’m not affiliated with that company. I’m just a gardener that’s gone down the water rabbit whole for many years! I’m very wet! Ha! JK. For thousands of years people have made reference to living water. It has spiritual as well as philosophical and scientific connotations. The fact that the term has survived so many generations is an indication of deeper significance. It implies there is living water AND that there is something other than living water. Can water lose its life? If so, can the life be returned to water? These are powerful questions that deserve more than philosophical answers. Dancing with Water: The New Science of Water is an investigation into water’s liquid crystalline phase where water molecules exist in a repeating geometric array similar to the molecular pattern found in a solid crystal. Although the molecules remain independently mobile, they respond as a coherent “whole.” This is living water–an organized network that responds to its environment carrying signals and supportive vibratory information to the life forms it supports. Living water has existed on Earth for millions of years. As the foundation of life, it is one of Mother Earth’s finest creations. But the degree to which water can support life depends on the degree of life force in the water. Water can be vibrantly alive or it can be barely alive, just like the inhabitants of the Earth. Although much of the water on the planet today has been mistreated to the point that its life hangs by a drop, understanding a few simple concepts can return water’s life force. The first step is to restore the liquid crystalline network. Then, the addition of frequencies/information completes the task. The term, full-spectrum living water is a phrase used by the authors of Dancing with Water to refer to living water that carries the full spectrum of life supporting frequencies. Several factors contribute to the overall process. Movement or turbulence – which creates vortices. Some form of gentle, organizing energy (this can be supplied by magnets and paramagnetic materials some geometric shapes and many methods of concentrating life force (for example, orgone energy devices Mineral ions (salts). These anchor the life force in water and help water to hold vibratory information. Stillness — a period following movement during which water develops coherence. Vibratory information — frequency-based input, including the very important resonance of the Earth. When these elements come together (and they can do so in many ways) water becomes a living, liquid crystal with the full spectrum of life supporting enhancements. The process is outlined in the book, Dancing with Water, with instructions for providing these elements in such a way that they result in full-spectrum living water—Earth’s finest gift—water that supports life to its fullest. That’s all from her website… great stuff. Investigate your own local water before you go slamming too much of it. And look at the pipes in your home. Hard water (like my town) has tons of great minerals in it but lots of fluoride too. Thyroid crusher! You may be able to set a two liter of your tap water out over night and off gas a lot of the chlorine gasses and get pretty decent water. Drip coffee is a good way to filter water and transform it into food! Yay! ️
  • F

    liquid thyroxine source in Europe?

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    F
    @CrumblingCookie liquid because i stopped absorbing thyroxine tablets, probably something to do with gut where its absorbed pfff, i take ndt and it raise my t3 well and aliviate some symptoms but not all of them, i need to raise total thyroxine serum. its taken sublingually
  • EPSTEINE

    Cigarette smoking and DNA methylation

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  • lobotomizeL

    intresting chems source bounty

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    U
    @lobotomize in bounty coconut+chocolate bars?
  • W

    Ray peat perspective of showering daily

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    JenniferJ
    Not about the effects of showering, but I came across this Q&A on body odor that I thought was interesting: Question: Does Ray have any thoughts as to why taking supplemental T3 may cause a negative change in body odor?" Negative being worsening? That's what I assume. Ray Peat: Yeah, it can increase your sweat production. Just taking one or two showers with 10% sulfur soap can eliminate permanently a bad balance of bacteria on your skin and can make a difference in the odor of your body, the sweat for a long time. https://bioenergetic.life/transcripts/d9973?t=3860&c=96
  • EPSTEINE

    Chudenergetics

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    C
    @lykos this is what true peating is about
  • W

    The origin of mortal existence

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  • sunsunsunS

    This topic is deleted!

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  • engineerE

    Peating is absolutely UNBELIEVABLE

    health energy peat fitness
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    H
    @sunsunsun Do you want attention or why do you behave like this?
  • EPSTEINE

    Has anyone improved their health by peating

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    EPSTEINE
    @alfredoolivas needs more iphones
  • W

    Aspirin timing for lower cortisol/better sleep? Currently 250mg morning + lunch

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    W
    @DavidPS thank you!
  • W

    15yo Son on Ray Peat Protocol

    bioenergetic young hormones raymond peat
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    @williambjr said in 15yo Son on Ray Peat Protocol: @Peatful i let him eat as much as he wants. I just didnt mention it Perfect
  • EPSTEINE

    Why yes i am peating how can you tell

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    alfredoolivasA
    @sunsunsun [image: 1767911816711-08f0bf04-ca24-40fa-a367-51a962d1a1d2-image.png]
  • I

    Dr. Paul Saladino appearance is much older after a relatively short passage of time but why?

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    sunsunsunS
    @alfredoolivas idk
  • gg12G

    Ray Peat discord

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    engineerE
    @sunsunsun said in Ray Peat discord: @engineer im actually learning rust rn xDDDD Sorry but I had to downvote this [image: 1767470757490-4002.png]
  • gg12G

    Estrogen -> How a man is created

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    U
    @gg12 said in Estrogen -> How a man is created: If you are exposed to high estrogen/stress you will have strong impulses to do things like: 1.be overly aggressive / hostile / controlling 2. Assume you know everything 3. Feel pity for yourself 4. Have a strong urge to fap and watch porn 5. Try to avoid further stress. But if you do not act on these impulses you will become stronger. When people take testosterone they have the concern of not being able to produce it naturally when they stop taking it. So what if you reverse engineer it. What if you purposely face the estrogen. As soon as you are not exposed to it you will feel great vitality and strength. Obviously you don't want to be in this catabollic state 24/7 like brute deforce talks about. But you really think you can avoid stress? May as well be the overman, so go under first. Hi, what is facing the estrogen?
  • cs3000C

    #11 Malate / malic acid

    malate malic acid mitochondria complex inflammation
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    ChudC
    purebulk sells magnesium malate for dirt cheap https://purebulk.com/products/magnesium-malate