Histamine is a stress signal Iirc it also turns on NO You are under metabolic stress You need to energize cell function I am simplifying this a lot…. 1- blood sugar. 2- endotoxin. Start there If you raise your metabolic rate Naturally- not with exogenous t4 But sugar Sugar supplies your liver and thyroid essential metabolic support It’s a pillar of Peats teachings Addendum: not glucose supplements

@Gardner i ate four pita wraps last night after already eating a peaty meal of greek yogurt and cooked fruit , i noticed zero downside to the wheat flour meal vs the peaty dairy + fruit meal all of this is possible due to mogging timeline once u begin to mog it doesnt matter , i suspect even some pufa deep fried food is ok, but it grosses me out to think of eating deep fried pufa oil tbh so i havent tried

@lobotomize I was being sarcastic but, so, what I meant was, you are smarter meaning the brain is in like an excited lots of blood glucose from the cortisol adrenal realize. I’m not saying that’s a good thing or healthy but it does happen.

@bio3nergetic you are right apologise i wrote that in a hurry

There's something fishy about this story.

Thyroxine is T4 - it is best to use both T4 and T3 in the right ratio. I have written a book about thyroid replacement therapy - it also presents Dr. Ray Peat's protocol for using T4+ T3. The title of the book is: "How to Use Thyroid Medication." It is helpful for anyone who wants to use thyroid medication correctly. You can get it on Amazon. I spent more than three years researching for this book in hopes of helping people who are confused about thyroid medication - I hope it will help. You are also welcome to contact me via my website: https://biochemnordic.com/ [image: 1773483570697-how-to-use-thyroid-medication-ray-peat-resized.png]

@engineer https://bioenergetic.forum/topic/9249/nnos-a-useless-harmful-byproduct

@cookielemons Only 2 minerals are used in bone mineralization: calcium or phosphorus. As metabolism decreases, bone mineralization via phosphorus increases. For a brief correlation: older people have a higher phosphorus to calcium ratio in the bones than young people (who have higher calcium in the bones), and older people also have more bone fractures than young people. For the amount of phosphorus naturally occuring in the diet, it's actually pretty hard to balance it on a 1:1 parity with calcium, which is a way more important balance than with magnesium. High dietary calcium does not cause a problem, you urinate out excess. PTH causes all kinds of problems with calcium metabolism, tho. PTH raises when dietary calcium is low, and this forces calcium rich tissues to dump calcium into the blood, and for calcium uptake everywhere. It's an emergency response and redistribution by the body because of how vital calcium is for metabolism and the heart. If dietary calcium is not present, supplemental vitamin D can place higher demand on calcium, which will raise PTH to get it, and this cause the afformentioned problems. This is not Peat's crazy ideas he just made up. I can't remember the Japanese researcher, but he got a nobel prize for his research on calcium metabolism. Peat referenced his work. Peat is on the ball with calcium metabolism. While it's totally possible to be so low in magnesium, and metabolism be so retarded, you could possibly cause problems, it's possible you just weren't eating magnesium rich foods. Kidney stones are actually created by elevated PTH -- this is paradoxically caused by low dietary calcium. Toying with mineral balances is mostly what it sounds like: playing wackamole -- because minerals can never be regulated effectively until thyroid is addequate. the body doesn't feel the presence of a high calcium food and go "oh no, need more magnesium." Storage, utilization, and/or discarding of nutrients, is a constant automatic process. Either the metabolism is functioning to do this, or it's retarded. hand-selecting the nutrients to attempt to bypass this has little basis in reality as far as I understand it. Sodium and calcium are the only minerals you really have to conciously consume in accute weigh-able amounts, the rest come from a nutrient dense diet. They function like a chemical, directly impacting physiological processes. Sodium turns off aldosterone, a vasoconstricting hormone. Calcium lowers PTH, a calcium leaching hormone. Both of these are stress hormones. Between coffee, milk, OJ, oysters, and liver, you should hit your other mineral intakes decently well.

Which nutrient to dampen glutamate in manufactured food, except taurine? I've got this info on my PC. Several nutrients and compounds can help dampen the effects of free glutamate(MSG) in manufactured food, primarily by blocking receptors, assisting with conversion to GABA, or reducing neuro-inflammation. Here are the key nutrients and compounds, excluding / in addition to taurine: 1. Primary Nutrients to Dampen Glutamate  Magnesium: This is considered a critical nutrient because it directly blocks the NMDA (N-methyl-D-aspartate) glutamate receptor, preventing the excitotoxicity caused by excess glutamate.  Vitamin B6 (as P5P - Pyridoxal 5'-phosphate): This is an essential cofactor for the enzyme Glutamate Decarboxylase (GAD), which converts excess glutamate into the calming neurotransmitter GABA.  Omega-3 Fatty Acids (EPA & DHA): These fatty acids, particularly DHA, are crucial for membrane health and have been shown to protect against MSG-induced neurotoxicity by supporting astrocyte function, which clears excess glutamate from the synaptic cleft.  Vitamin C : This acts as an antioxidant that attenuates NMDA receptor activity and helps increase glutamate reuptake from the synaptic cleft.  Vitamin E: As a lipid-soluble antioxidant, it helps reduce neuroinflammatory responses and increases the activity of glutamine synthetase, which breaks down excess glutamate.  Riboflavin (Vitamin B2): This supports the conversion of B6 to its active form (PLP) and helps prevent the buildup of neurotoxic homocysteine. 2. Functional Foods and Additives  Theanine: A compound found in green tea, it lowers glutamate activity in the brain by blocking receptors while also boosting GABA levels.  Ginger: Studies have shown that ginger significantly reduces MSG-induced elevated levels of glutamate, sodium, and calcium in the brain.  Curcumin (Turmeric): Known to attenuate MSG-induced neurotoxicity, reduce glutamate levels, and protect against inflammation.  Probiotics (Lactobacillus and Bifidobacterium): Specific strains express glutamate decarboxylase (GAD), which can convert ingested glutamate to GABA in the gut. 3. Other Protective Agents  N-Acetyl Cysteine (NAC): Helps the body regulate glutamate levels.  Zinc: Protective against neuronal excitotoxicity.  Coenzyme Q10: Reduces glutamate-induced cell death. Summary Table of Protective Action Nutrient/Compound Mechanism to Dampen Glutamate Magnesium: Blocks NMDA receptor Vitamin B6: Converts Glutamate to GABA Omega-3:Enhances glial uptake Theanine: Blocks receptors/boosts GABA Ginger: Normalizes glutamate levels Vitamin C/E: Reduces neuro-inflammation Sources and References Micronutrients May Be a Unique Weapon Against the Neurotoxic Triad of Excitotoxicity, Oxidative Stress and Neuroinflammation: A Perspective doi: 10.3389/fnins.2021.726457 Front Neurosci. 2021 Sep. https://pmc.ncbi.nlm.nih.gov/articles/PMC8492967/#:~:text=Riboflavin may also be able,protective function of vitamin D. Excerpt Riboflavin may also be able to directly affect excitotoxicity by inhibiting the exocytosis of glutamate vesicles in presynaptic neurons (Wang et al., 2008). Finally, riboflavin (along with PLP, folate, and vitamin B12) also has the ability to help protect against homocysteine build-up (Rozycka et al., 2013). Homocysteine has been shown to be neurotoxic via its ability to act as an agonist at the NMDA receptor (Deep et al., 2019), making riboflavin’s ability to reduce homocysteine very valuable. Riboflavin additionally has the ability to protect against neuroinflammation. First, riboflavin was shown to effectively reduce TNF-α, IL-1β, and nitric oxide (NO) in a staphylococcus infection model (Dey and Bishayi, 2016). Riboflavin also plays an indirect role for opposing inflammation through its effects on vitamin D metabolism. Multiple enzymes in the biosynthetic pathway of vitamin D are dependent on riboflavin for their action (Pinto and Cooper, 2014). Animal models have been able to induce vitamin D deficiency from riboflavin deficiency due to this effect on the internal synthesis of vitamin D (Pinto and Cooper, 2014). Since vitamin D has anti-inflammatory effects (as detailed above), riboflavin deficiency may inhibit this protective function of vitamin D. GABA: What Is It + Its Balance with Excitatory Glutamates Dr. John Gannage. Arkham Integrative Medicine Excerpt A 2020 study published in Translational Psychiatry has demonstrated that altering synaptic excitation-inhibition balance by potentiating GABA was associated with a significant reduction in ASD symptom severity (14). Interestingly, the first nutrients in the biomedical world proposed for the treatment of ASD over 50 years ago by Bernie Rimland were magnesium and B6. Magnesium blocks glutamate uptake through the NMDA receptor and B6 (pyridoxine) is a GAD co-factor for converting glutamate to GABA. The amino acid taurine is also GABAergic and commonly recommended by functional medicine practitioners for children on the autism spectrum with behavioral issues and hyperactivity. ASD = autism (stands for autism spectrum disorder => dissociative identity disorder). 3) Natural products as safeguards against monosodium glutamate-induced toxicity doi: 10.22038/IJBMS.2020.43060.10123 Iran J Basic Med Sci. 2020 Apr. Chemistry of MSG explained. Toxicity and side effects. Protective effects of plants, food, vitamins and natural compounds.

https://www.youtube.com/watch?v=VTchFM3wb68

@alfredoolivas just bribe you doctor if you rich enough to import t3

@cyberpeater22 said in is juice from concetrate good: No, why? You asked for advice and afterwards you became suspicious, not to say more. The same behavior ...

you aren't thinking coherently or logically. your logic is flawed and biased, just my 2c. Hope you would rethink this biased emotional behavior controlling you, it would benefit your future greatly.

@dapose i am too much of a retard to deal with making coffe in various way, and instant coffe tastes sour, thanks for your advice

using Mg topically is the only way it really works for me. I hate the feeling so I spray it on and rinse it off about 15-20 minutes later. I use it at nigh and mostly on my legs. If I'm lazy I just wipe it off with a wet cloth. If I don't do it I also get a nasty rash. I don't get a rash on my legs either but I do on my stomach and arms, even for a shorter time. Just my experience.

The alibaba stuff will need to be analysed with a CoA provided by the seller/producer of their previous batch before ordering, and again of your batch before shipping, of course. Just as with the US company you've found. To double-check you could then order an additional non-GMP IR-spectrography or NMR or LC/MS for a couple to few hundred bucks after you've received the product. If the substance is neither listed on any prohibited compound lists nor within the registry of pharmaceuticals the chances of it passing through should be good but always subject to the general degree of arbitrariness.