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  • Scientific papers, books, blog posts. Discussion of whatever you find interesting and notable.

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    TexugoDoMelT
    @sunsunsun said: @TexugoDoMel https://pubmed.ncbi.nlm.nih.gov/8406319/ That's really interesting about the thymus, it makes you wonder about the effects of so much estrogenic substance starting in childhood. But any stress related situation could increase it I think. But when it comes to muscle, the ability to bind to GR isn't even among the top two ways that counteract catabolism IMO
  • Websites, newsletters, articles, podcasts, interviews, explainers, books, and other resources that relate to the work of Dr. Raymond Peat.

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    C
    Cancer Treatments – from Research to Application MCS Foundations for Life, In memory of my dear wife Mihaela Catalina Stanciu https://www.cancertreatmentsresearch.com/ https://jeffreydachmd.com/cancer-articles/
  • Do you have a question? You can post it here, but you will only receive unqualified personal opinions and NOT medical advice in any shape or form. If something seems like medical advice but it's posted in this category, it's actually a personal opinion.

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    adrn100kA
    I talked to Danny Roddy via Patreon, and he told me it could be a defensive reaction to stress. Essentially, the body ups its protective hormones when challenged. In my case, it applied to elevated serum progesterone in hyperthyroidism, which I developed after elevating my metabolism with Cynoplus, while probably lacking necessary resources. Finasteride's endocrine-disruptive effects are well known, and in case of the high E2, stress is very likely. Danny also said supplementing progesterone could lower serum progesterone, but I haven't tried that and would obviously be vigilant about taking exogenous hormones. The wording is a little unclear, did your progesterone elevate after taking Finasteride, or was that an issue you had before? I can also really recommend booking a consultation with Danny, although it is pretty expensive ($150).
  • From medical devices to supplements. Red lights, CO2 tanks, large trash bags, kuinone, and more.

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    LucHL
    @jd_au said: My problem is, I've been on a high milk and fruit diet for years. But it was only when I started supplementing with additional vitamin C that my longstanding issue of blood in the nose and gums resolved (practically overnight). The problem is not vit C. it's the kind you use and the way you eat. Molecular integrity. Residues, even when labelled "natural" or plant based (acerola). And by the way, for other readers, mind the kind of "vitamin C" powder you buy, without a certificate (HV and real AA). Fake AA is at least 50 % rubbish. I can give a link if interested.
  • Recipes, food, meal prep, brands. Discuss them all here.

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    MossyM
    @Jennifer I was just considering today whether to use red or gold potatoes for potato salad.  I think I will try the gold this time.  Another consideration is whether to leave the skin on or take it off.  I think it's kind of Peaty to take it off, but maybe after cooking, the benefit of nutrients in the skin outweigh any trouble they may present to digestion. Only 300 years?  Haha, kidding of course.  That is some history.  And the scenery sounds just as one would want a 300 year old farm to be.  Interesting...biological transmutation.  That substitution effect of minerals in the biological process make sense, if what I remember Ray saying is correct, something about taking some extra salt, to help balance out minerals in the body.  I do need to look into Kervran. I'm with you on real food.  That is my goal as well.  Not just for quality, but for taste as well.  That is the first I've heard of the brand NestFresh.  I'll keep an eye out for them.  I do like the ethical aspect, but they'll have to wait until my food budget changes. That makes sense to me, that a person's intuition would guide them in what to choose to eat.  That possibly being rooted in heritage and genetic make up, which I think would be consistent with the Metabolic Typing Diet.  I've mentioned this some time back, maybe on the RPF, but I think that kind of diet would be contrary to Peat's perspective, if I'm recalling properly.  I think Peat doesn't like the idea of allowing genetics to determine what we eat or how to approach our health.  Or maybe I'm getting my information crossed.  Too much reading!  I've eaten plantains both overly ripe and starchy, green.  I would estimate that the majority of the time, I ate them overly ripe.  As you say, very sugary and spongy.  I think they're a great compliment to proteins, especially meat. I forgot about cooking potatoes in the microwave.  I've done that in the past.  I now primarily cook them in an Instant Pot or bake them in the oven.  I've come back to the microwave after not using it for about 10 years.  I have an EMF meter, and can tell you definitely don't stand in front of it while it's on; and even standing close to some components, while not running, give off EMF levels you don't want. I get that, about heaven and hell being energetic states of being.  I don't think that idea is inconsistent with the historical, Biblical versions.  Trouble in our lives is "hell on earth", and as you say, love "feels like heaven".  These for sure are states of energy, that can significantly affect us. I personally can reconcile these analogies with literal counter parts.  For if there is a hint of something, there must be a more certain and fuller version of it. Indeed.  I do think it's good we are being a good son and daughter to our dads.  And it's okay that we do our duty, apart from always being conscious of it.  Actually, it's probably preferred we don't over think things.  Neurosis is easy for an overly sensitive person.  Combine that with our overly stimulated world, and over thinking is easy to do.  You speak of being like water, being able to adapt and thrive within our challenges.  I see a calm mind and proper thought as part of that.
  • Discussing pistol squats, concentric exercise, resting, and other forms of strength training.

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    C
    I thought aspirin and/or baking soda w water is good for afterwards? Gummy bears or fruit before and during lifting, no?
  • Cancer (AML)

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    @thibaud I found a post in the old forum where someone submitted their email exchange with Ray Peat. Hope it helps: Post in thread 'Ray Peat Email Advice Depository' https://lowtoxinforum.com/threads/ray-peat-email-advice-depository.1035/post-119453 I don't eat liver as it makes me very nauseas but I could try brewers yeast if it is useful for something? I haven't tried B1 or pantothetic acid. Would this be in addition to brewers yeast? I don't currently use aspirin but am trying to source a pure form in the UK. Would you be able to provide approximate doses for all of the above please and let me know what they assist with? Ray Peat said: Vitamin B1 helps to oxidize glucose, so if you try 50 or 100 mg with a meal you should watch for possible hypoglycemia from the insulin. Pantothenic acid is safe in doses of 100 or 200 mg, and helps to limit hypoglycemia. Brewers' yeast has other nutrients that help with repairing the pancreas, but can cause gas, so it's best to start by pouring hot water over an ounce or two of it, and using just the liquid.
  • Mitochonic acid

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  • How to prevent and reverse skull expansion? (Hair loss)

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    LetTheRedeemedL
    @risingfire brought the final boss variable compounder
  • Stopping Antibiotic Course

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    M
    @Meeka I stopped taking it early and felt better within a couple of days. I was prescribed it again after that and only made it through one dose. I won’t be taking that antibiotic again.
  • This topic is deleted!

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  • Jordan Peterson dying from akathisia.

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    alfredoolivasA
    [image: 1776786468717-a4097f4b-73f2-4c4b-a340-db6378d8681d-image.png] JP is doing everything to not go back to this.
  • opinion on whey protein?

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    sunsunsunS
    @Milk-Destroyer not really, just as a convenience to add to oatmeal if i dont have eggs for some reason. there’s no point when i can just drink 1L of milk for a protein drink giving 36g protein.
  • Hypothyoidism and overschdeuling yourself?

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    JenniferJ
    What risingfire said. With thyroid energy, I feel like I have all the time in the world, like I did when I was a child—it’s as if time moves slower when my thyroid is functioning optimally—and I feel an excitement to do things, but it’s accompanied by this sense of calm or peace, while adrenaline energy feels like there isn’t enough time in the day to get everything I want done, like time is flying by, and there’s usually this background feeling of anxiety, a fear of my own mortality, really. With both energy sources, I have moments of euphoria, which made distinguishing between the two and adjusting my diet and thyroid dose accordingly quite challenging in the beginning so going by my temps (including temps of extremities—cold feet, hands, nose and/or ears are a telltale sign that adrenaline is compensating for thyroid and cutting off circulation to them to keep the core and vital organs warm), pulse rate and slightly more involved but very helpful is evaporation rate, i.e., average total fluids consumed and eliminated via sweat vs urine in a 24 hr period.
  • Oral va Topical.

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    @alfredoolivas yeah im aware. Me and my son use this account. We are not on here though mainly the raypeat forum. And the reason i give him t3 is because his ATP production is bad.
  • does glycine increase need for caffeine intake?

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    alfredoolivasA
    @LucH Why is your AI so fucking chill?
  • the last piece of the peaty puzzle ? simplified with ai

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    B
    This picture of VDR knockout mice being "lean" and "obesity resistant" is taking some of the trees for the forest and claiming it's the whole forest. If you are insulin resistant, generally force-feeding a lot of carbohydrate substrate without any other measures is probably not a good idea. Are carbohydrates bad? No. Vitamin D has been skewed, I am sure intentionally, as a general calcified public is also "paradoxically" calcium deficient, or more aptly on a very low calcium:phosphate ratio, focusing on inflammatory, active D (1,25) paints the perfect, evil picture of vitamin D overall and is frankly wrong. Hydroxylases tightly regulate local conversions to 1,25 from 25. What interrupts this regulation? Calcium deficiency, estrogens, PUFA. In other words pre-inflammatory state. Knockout mice, barring all other factors of health - which is usually the game here in these worthless studies - will not experience this inflammatory, dysregulated system. And looking only at this narrowly through a lens, you derive your conclusion you are looking for: manipulating the meaning and function of things. In reality, in the real world, the better method in avoiding these inflammatory responses is, you guessed it, sufficient calcium, low PUFA, in turn keeping estrogen in check, and being careful of other inflammatory things. Much like the knockout mice scenario, removing some apparatus to prove something is bad, when that something itself is hijacked and fed into a detrimental cycle is a sleight of hand, not proof. Vitamin D is not the problem, and VDR knockout doesn't prove it is, only in that if 25 is converted via inflammation. Lipopolysaccharide derived MKP-1, inhibition by inactive D already shows vitamin D is an anti-inflammatory, but not 1,25. And 1,25 is one of the resident experts of inflammation, when conditions of health are not met. Get tho9se conditions met and D does what it does that is good for us. By the way, progesterone and methylene blue also help Also, "constant milk intake" is an absurd, hyperbolic suggestion. I am certain nobody here has an IV of milk coursing through their veins 24-7. You have some milk throughout the day, then we all fast whether we know or not: it's called sleep.
  • Something to know about i.p vs oral dosing animal studies

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    Probably because the cells utilize more sugar as a concerted effort to recover from infection. If we picture a U curve, with the state of infection being one extreme side, more sugar would perhaps satiate the need to recover from infection with the surplus leveling out for glycogen formation.
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    cs3000C
    Acute first aid treatment after brain injury Case Report: Buccal administration of hydrogen-producing blend after a mild traumatic brain injury in a professional athlete https://pubmed.ncbi.nlm.nih.gov/32595937/
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    @cs3000 any update on your electrical symptoms from sunlight and vitamin D?
  • WARNING Alkaline environments hyper-accelerate the Maillard

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    LucHL
    @lobotomize said in WARNING Alkaline environments hyper-accelerate the Maillard: aspirin also does the blocky thing Yes, very useful but we have to manage the impact on platelet renewal, whatever the dose is. 10-12 days to recover a functional system. I can give a link if interested.
  • strong histamine reaction after startingh levothyroxine...

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    Histamine is a stress signal Iirc it also turns on NO You are under metabolic stress You need to energize cell function I am simplifying this a lot…. 1- blood sugar. 2- endotoxin. Start there If you raise your metabolic rate Naturally- not with exogenous t4 But sugar Sugar supplies your liver and thyroid essential metabolic support It’s a pillar of Peats teachings Addendum: not glucose supplements
  • Still Haven’t Found a Perfect Food, Does It Even Exist?

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    sunsunsunS
    @Gardner i ate four pita wraps last night after already eating a peaty meal of greek yogurt and cooked fruit , i noticed zero downside to the wheat flour meal vs the peaty dairy + fruit meal all of this is possible due to mogging timeline once u begin to mog it doesnt matter , i suspect even some pufa deep fried food is ok, but it grosses me out to think of eating deep fried pufa oil tbh so i havent tried
  • Why am i smarter when sick/histamine?

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    daposeD
    @lobotomize I was being sarcastic but, so, what I meant was, you are smarter meaning the brain is in like an excited lots of blood glucose from the cortisol adrenal realize. I’m not saying that’s a good thing or healthy but it does happen.
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    lobotomizeL
    @bio3nergetic you are right apologise i wrote that in a hurry