@DkJoe2 I wonder if exogenous l-dopa would convert instead to adrenaline though? And is tyrosine use safe, it being a standalone amino-acid? I suppose it'd be a matter of individual experimentation

@leon-damjanov, it sounds like you run on stress hormones to compensate for poor thyroid function. Adrenaline raises temps and lowers TSH, giving the false impression that thyroid function is good. The biggest give away to me are cold extremities. Adrenaline cuts off circulation to extremities to keep vital organs warm when thyroid function is poor. The stress of darkness and fasting at night may be triggering adrenaline, causing your temp to be normal in the morning, while eating throughout the day lowers adrenaline, resulting in lower temps and revealing what your actual thyroid function is. Regarding weight, I’m thin, consume a lot of calories for my size and activity level, and have a history of running on adrenaline due to a weak thyroid. Ray Peat talked about people like us whose hypothyroidism often goes untreated because we aren’t overweight.

A lot of bone broth, potatoes, pot roast, cheese, sourdough bread. I essentially adopt what you would expect an English medieval peasant to consume

@mavuue

You have to go back to the time your CBC blood work began to show these poor numbers and retrace to that time to figure and out what changed in terms of sickness, a change in lifestyle etc

This way, I can hazard some guesses on why your blood work took a turn south

@Insomniac cool thx

my urine is a deep yellow and it seems structured. like, times I am stressed and peeing frequently and light coloured, it is basically like water in texture. when I am feeling good and urinating my urine shimmers and when I touch it, it doesn't feel like plain water. It is structured cellular water.

I know all this because I pee in a cup then pour it down the drain.

@Rayoshi-Pufamoto just do the food sir. maybe 1 deop of k2 mk4

@Goodman said in Why did Ray Peat change his mind on sugar:

From book "Nutrition For Women" by Ray Peat, "I have seen publicity about something called the NASA astronauts' diet, and was impressed by the large amount of refined sugar in it.

He wasn't impressed with all the research from NASA. He considered HRV (heart rate variability) a fad. But HRV is the glue of of ringcore that began with the Oura ring. But all it is is glorified old heart rate measurement technology derived and spun into a hodgepodge stew of questionable biomarkers that is more marketing than science, based on it being from NASA 'rocket science.' Dressed up additionally in the garments of AI, it should keep selling well into the age of wearables with brands like Polar, Samsung, and Apple joining in the fray.

@Pooooop
-sun room
-plants
-high in the mountains
-warm
-good air flow
-access to natural bodies of water
-sense of community
-colorful scenary
-unique/personality

@Chris2401 I do a sort of combination of randle cycle, peating, and raw till 4 lol. Fruit, sugar, honey, and juices all day long with one cooked protein/fat heavy meal.

Btw theres some fuckery going on with some popular supplements, one i got didnt dissolve in water (not gaba)

Things like this keep me up at night. How many kilos of powders from china have I eaten over the years? I don't even want to think about it. Horrifying

Some good info here https://www.tcoyf.com/fertility-info/

The molestation I experienced began around age 5 and went on for years. I remember in great detail what happened, what I was thinking while it was happening, but it doesn’t carry with it the energetic weight it used to. I feel nothing now when I think of it and the one who abused me. I’m not angry, resentful, distrustful of all people. I am, however, more aware of the read I get on people, sensing their energy, and I trust my instincts. I can share in detail an example if anyone thinks it would be beneficial to the discussion, but I’ve avoided being assaulted as an adult many times because I don’t write my feelings/intuition off as an unwarranted side-effect of being abused, something that happens far too often because of common beliefs, and assumptions made, about women who have suffered abuse. Jokes about women with “daddy issues” comes to mind.

My family life was and still is challenging, but that’s life. There will always be challenges in relationships, however, the difference now is how I respond to them. Now I’m honest about my feelings—for better or worse, I don’t hold back—and I’m able to let harmful relationships go. I thought for sure that I was going to take my “shameful” secret with me to my grave and would forever fear my words, associating them with death because I grew up with a mother who was suicidal and understandably she was easily triggered, but my filter broke when my spine collapsed in my late 20s and my truth came out. The physical pain of the disease and subsequent injury were unimaginable, but I know it happened for me, and for those I have helped because of it.

@mavuue Hmm i guess you could experiment with coming off. It would only take like 2 weeks max for natural thyroid function to re ignite

@BioEclectic said in Does anyone take a multivitamin? What to look for in it?:

interesting note about the B50 complex. I recall you mentioning before but i don't recall the backup detail (?) That potentially harmful?

AMPK sensor: Friend or foe?
@BioEclectic
Starting point: Too much of a good thing can become counterproductive (cancer).
BioEclectic, a forum user on bioenergetic.com, recently asked me why it was not appropriate to regularly take a complex Vitamin B50 supplement. OK if it's 2x/week or these are the RDA if taken regularly, knowing that we will then have chosen a co-enzymated form (with cofactors), without yuck ingredients. (…)
Short answer:
AMPK functions as an energy sensor in our cells. This sensor plays a key role in the balance between anabolic and catabolic programs for cellular homeostasis in response to metabolic stress.
In the case of a tumor, the cancer cell attempts to slow down oxidative metabolism and works to divert the supply of glucose for its own benefit in order to grow. The cancer cell will therefore try to down-regulate the influence of AMPK, which acts a little too much like a traffic agent to supply the different organs, instead of promoting the flow of fuel to the advantage of his own needs.
So, what the link with cancer?
Taking high dose of thiamin (B1) or pyridoxine PLP (B6) – they are just 2 examples of antioxidant – they act to moderate the AMPK sensor, to dampen the effects. Right in cure or if the dose turns round RDA but not for prolonged use.
Reactive oxygen species (ROS) are continuously produced as a by-product of mitochondrial metabolism and eliminated via antioxidant systems.
Cancer cells try to moderate / neutralize anti-stress.

Full answer on my forum, with link in English and in French (translator needed).

Cancer cells are usual, at a certain age, and have to be considered “normal” if the size does not exceed a €2 coin… AMPK as a regulator of energy metabolism How much B vitamins do we need, in which proportions? How can we modulate the sensitivity of the regulation? Cancer cells divert the supply of fuel and try to avoid oxidative stress. What’s the link between B1 and cancer growth? Targeting the AMP-Activated Protein Kinase for Cancer purpose?

@Goodman
How much caffeine is too much for a pregnant woman? I'm scared this might have happened to me, although I was born normal, it could have affected my brain.

@raytreats I eliminated my chronic anger with dextrose. I am more resilient to stress than I have ever been in my adult life.

A meetup is definitely a great idea, kudos for putting this together

You'll want plenty of Vitamin E to protect from the fat you are releasing as you lose weight.

I also love theanine after workouts. It helps to reduce serotonin and estrogen.

I prefer 0.7g protein per pound of your target bodyweight.

It would help to know how heavy you are now and what you plan to do to lose the weight.

You should avoid steady-state cardio except as walking. I would do HIIT sessions on an exercise bike 3x/wk and lots of walking. Walking outside will do the most for you but in the gym you should walk at a steep incline on the treadmill to burn the most calories.

You'll want to keep your muscle until close to you weigh-in date, but high reps will push more fluid into them without boosting their metabolic rate. Stick to 1-3 reps per set.