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  • Scientific papers, books, blog posts. Discussion of whatever you find interesting and notable.

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    MauritioM
    α-Ketoglutarate promotes amino acid depletion and suppresses B-cell lymphoma growth and development https://pubmed.ncbi.nlm.nih.gov/40700634/
  • Websites, newsletters, articles, podcasts, interviews, explainers, books, and other resources that relate to the work of Dr. Raymond Peat.

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    KilgoreK
    "GENERATIVE ENERGY: Restoring The Wholeness Of Life" is also now available. Amazon: https://a.co/d/jca7Tqh
  • Do you have a question? You can post it here, but you will only receive unqualified personal opinions and NOT medical advice in any shape or form. If something seems like medical advice but it's posted in this category, it's actually a personal opinion.

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    LucHL
    @alfredoolivas and @hwisdom Why you should give a try with WWB. We’re not talking about a crisis drug stuff. Since ASA (acid acetyl-salicylic) has an impact on platelet aggregation (for sure) and a possible by-side effect on mucin (epithelial protection of the linen intestinal walls) (aggressive and disruptive), we should learn how to manage to minimize the contraindications’ from these molecules. I’ll give the direction where we should look at, not in details now. There is an impact of ASA on platelets, and thus blood fluidity. Possible interaction with liposoluble vitamins? Useful links on ASA & WWB *) Impact of HD aspirin on platelet aggregation curve https://mirzoune-ciboulette.forumactif.org/t2143-english-corner-impact-of-hd-aspirin-on-platelet-aggregation-curve?highlight=platelet *) English corner: Aspirin cuts the spark; vitamin K keeps the current steady. https://mirzoune-ciboulette.forumactif.org/t2144-english-corner-aspirin-cuts-the-spark-vitamin-k-keeps-the-current-steady#30424 Prevention for SARS-cov-2. Vitamin K does not trigger clotting, it only ensures that the clotting and anti-clotting systems work effectively. Vitamin K is an essential cofactor for the activation of several proteins. How MK-4 aids in redox recovery Does aspirin counteract GLA protein or osteocalcin? HD Aspirin take permanently inhibits existing platelets; recovery depends on new platelet formation (≈ 10 days). Whatever the dosage is (81, 325 or > 500-1000 mg ASA). Vit K enhances balance: Vit K is an essential cofactor for the activation of several proteins. *) Aspirin & Salicin from White Willow Bark – A Natural Path to Mitochondrial Vitality? https://mirzoune-ciboulette.forumactif.org/t2128-english-corner-aspirin-salicin-from-white-willow-bark-a-natural-path-to-mitochondrial-vitality NB: I'll begin with this new post: Salicin and WWB Talk with Gemini 3 https://mirzoune-ciboulette.forumactif.org/t2163-salicin-from-wwb-vs-aspirin#30570 Context Once salicin from WWB is converted (via hydrolysis and oxidation) into salicylic acid, it can interact with cellular energy systems in a few notable ways; often on a more mildly way. Uncoupling of Oxidative Phosphorylation (Mild effect and Adaptive). Inhibition of Mitochondrial Stress Signaling (NF-κB, TNF-α). Protection against Lipid Peroxidation. Stimulation of Pyruvate Utilization (no direct data, mildly apply) DOI:10.1136/jcp.54.7.553 Downregulation of iNOS and NO Overload (it supports mitochondrial longevity and cleaner respiration). Excerpt Salicin is hydrolyzed into saligenin (salicyl alcohol) and d-glucose in the intestines, primarily by gut bacteria (or enzymes). Saligenin is then absorbed into the blood and transported to the liver, where it is oxidized to form salicylic acid, the active compound with anti-inflammatory and pain-relieving properties. https://www.stanfordchem.com/salicin-vs-salicylic-acid-relationship-difference-uses.html
  • From medical devices to supplements. Red lights, CO2 tanks, large trash bags, kuinone, and more.

    370 Topics
    3k Posts
    alfredoolivasA
    @milkgains_bro That's what I'm saying
  • Recipes, food, meal prep, brands. Discuss them all here.

    228 Topics
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    GreekDemiGodG
    @engineer said in Fat. How low can you go per day?: @GreekDemiGod How big are you? Because that seems like a lot to anyone who's not the Hulk. I'm 75kg/165lbs so I'd have to go much lower, maybe 30g or less to feel low fat. I am not much heavier than you. 79 kg, or around 175 lbs. And I maintain my weight on 2900-3000 calories, but my fat intake is also quite high 85-90g daily currently.
  • Discussing pistol squats, concentric exercise, resting, and other forms of strength training.

    85 Topics
    1k Posts
    alfredoolivasA
    @sunsunsun Yeah but the bamboo shoots are wet and in BPA cans no? Can I order them fresh?
  • psychedelics & bioenergetics discussion

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    SugarS
    While LSD is intense, saying it's a portal to demons is religious nonsense, and of course that guy Owen, who ironically enough made the cover art for Bronze Age Mindset, has an entite page dedicated to Christianity I'd write his experience off as having a bad trip. Lots of people on X/Twitter like to sensationalize different concepts like demons and things being demonic. While some people might genuinely feel that certain experienced/drugs are demonic, it seems easy to just make stuff up and exaggerate for engagement. Make something sound more sinister and bigger than it actually is. Now if we're talking about facing our own demons, anxiety, fears, and of course our gut health, that's much more valid. People undermine the importance of gut health with things such as psilocybin mushrooms or LSD, especially LSD as its a much longer and more intense experience. LSD makes you understand the importance of your environment, your energy, other people's energy, etc. It can put your problems and what you've been neglecting doing in your life to the forefront. I'd say the normie LSD formula is think about bad thing, let that bad thing effect your mood, freak out about said thing, and have a bad trip. Of course there's bigger problems, lots of fear inducing propaganda, and general uncertainty in this world, but as long as you understand you must keep going and have a positive friend who knows how to keep you in a positive mood and mindset, you can put yourself back in the positive happy trip spot. A big thing for me was seeing how beautiful nature was and how dysfunctional a lot of humans are and human creations, LSD activates synaesthesia where you can feel what you see, and vice versa. I'd research more into synaesthesia honestly. Again, it all goes back to your environment, your mindset, way of thinking, your trauma, etc.
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  • Why is Aspirin encouraged but Ibuprofen is harmful?

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    johnJ
    also consider reading Peat's article on aspirin which discusses the benefits of aspirin as well as the marketing scheme behind the rise in ibuprofen. Aspirin, brain, and cancer.
  • Most bioenergetic country to move to

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    DakotaD
    @insufferable When I hear WV my mind goes to the DuPont scandal with PFAS, I think that something like that could have had a lasting impact on those community's in ways that we still don't understand. I'm sure there were higher rates of cretinism, etc. But I think the most bioenergetic country to move to would be somewhere with high elevation in Russia/Bulgaria since they already understand most of these ideas and have for decades and decades before many in the U.S. Carbon dioxide baths, man made pyramids, brain wave testing, orgone principles, etc. https://youtube.com/@bosanske.piramide?si=qHOOVVMy4TlYOwkc
  • Is Caloric Deficit Peaty?

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    ?
    @Alexander99 said in Is Caloric Deficit Peaty?: My point in the above post was more that you should have a calorie deficit when losing weight, but this is one, albeit an important one, of many factors in losing fat. The trouble with the idea of a "calorie deficit" is just how exactly do you figure out what that means for you? If you have dieted using calorie deficits in the past, your body can reset its metabolic rate so that you can withstand calorie deficit (=starvation/deprivation) better which means you would need to reduce the calories even further to get any weight loss. This also opens the way to lose muscle mass (from higher cortisol) instead of losing fat.
  • Maple Syrup

    sugar maple syrup
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    @magnuscoffee I love the taste, but the manganese content can be problematic. Manganese overload can be an issue if you get carried away with the fabulous taste and overindulge habitually.
  • Peaty tweets in video form

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  • Dry hands?

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    bradB
    @raytreats My skin started getting dry when I upped my metabolic rate. I needed a lot more vitamins. I started eating a can of oysters daily and it resolved very quickly. (Now I eat one a week.)
  • Does anyone actually shit after every meal?

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    S
    On good days, yes. When consistent with carrot salad and/or other antibacterial stuff
  • Thoughts on thoughts?

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    CiceroC
    Thinking about thinking is like, a koan. It makes my brain short circuit.
  • The carrot salad

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    AtlasA
    The most controversial question in all Peating
  • Is Ray Peat Legit? My thoughts:

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    KvotheK
    @honest_skeptic Ray always said that he wasn't a scientist and never really aspired to be one. He has always described himself as a painter/philosopher and/or a science critic. If you think that having some articles published on pubmed makes you a good scientist, you haven't really understood the main problem.
  • PEPTIDES INFO DUMP

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  • BAKING SODA CURES CANCER- The fungal nature of cancer

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  • FMT - A New Frontier in Digestive Health

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    SubTenderEnjoyerS
    I think FMT is a good option for gut treatment. It already has dozens of studies showing improvements of digestive diseases including Crohn’s. Here is one of them: https://microbiomejournal.biomedcentral.com/articles/10.1186/s40168-020-0792-5
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  • Mushrooms....peaty?

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    AdonisA
    @CheesedToPeatYou Indeed, that would be my answer as well, but has any amongst us drank directly from the chalice?
  • Pregnenolone and hair loss

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    bradB
    @Zeno My guess is it's suppressing estrogen, which can cause body hair. Not sure what's causing hair on head thinning. Have you tried the topical aspirin baking soda wash?