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  • Scientific papers, books, blog posts. Discussion of whatever you find interesting and notable.

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    chudlordC
    @jamezb46 is it not more likely that this is merely increased excretion rather than increased absorption?
  • Websites, newsletters, articles, podcasts, interviews, explainers, books, and other resources that relate to the work of Dr. Raymond Peat.

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    Cancer Treatments – from Research to Application MCS Foundations for Life, In memory of my dear wife Mihaela Catalina Stanciu https://www.cancertreatmentsresearch.com/ https://jeffreydachmd.com/cancer-articles/
  • Do you have a question? You can post it here, but you will only receive unqualified personal opinions and NOT medical advice in any shape or form. If something seems like medical advice but it's posted in this category, it's actually a personal opinion.

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    HarlockH
    Gm guys! I got cold urticaria when I am in contact with cold water, cold air, anything cold. Beside bad thyroid, what do you think could be the cause? Cypro works well but puts me in a really tired state that I can't afford. Thx a lot guys! [image: 1789697110092-whatsapp-image-2026-09-18-at-02.52.27.jpeg] [image: 1789697118682-whatsapp-image-2026-09-18-at-02.53.48.jpeg]
  • From medical devices to supplements. Red lights, CO2 tanks, large trash bags, kuinone, and more.

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    I was told, "Turkey tail mushroom powder is a ground dietary supplement made from the Trametes versi-color fungus, widely used to support immune function and gut health. The Japanese use this for cancer" Does anyone know anything about this? Being given to a pooch diagnosed with leukemia. Thanks
  • Recipes, food, meal prep, brands. Discuss them all here.

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    JenniferJ
    @Mossy, exactly, and for me, love is the main component—in practice, basing my choices on a love for myself (and others by extension—man being a strand in the web of life and all) and my life, not fear, has proven to be the most healing of all. I believe there is no higher vibration than God and God is love. Thank you for sharing The Four Loves with me. I found a free pdf of it on archive.org and am currently reading it. I had never read anything by C. S. Lewis before, but I was aware he was a Christian apologist so I had some idea of what to expect—I’m not Christian, myself, but having grown up in a Catholic family and attended parochial school, I’m familiar with the Christian concept of God. I think cold can have an effect on an egg’s cloudiness, too, because I’ve had cartons of eggs too close to the refrigerator’s fan that partially froze, and the half that froze and defrosted had very cloudy whites. It’s too bad you can only get the Nounós at Whole Foods. I’ve only found two stores here that carry it. If you can get your hands on Alexandre Family Farm’s whole milk yogurt and strain it, it’s similar. I used to strain the Alexandre’s, but it became too costly at $7.99 for a 24 oz container (roughly 12 oz after straining) daily. For comparison, I paid $5.99 for a 16 oz container of Nounós. No worries. I knew exactly what you meant by mushroom. I should clarify that my experience is not a reflection of the quality of lichen-based D3, but my health status, at the time. My thyroid was still recovering from the trauma of my mum’s passing and for whatever reason, when my thyroid tanks, I struggle with plants so practically everything plant-based was causing hives. I haven’t tried Haidut’s vitamin D, only because I like to take D3 orally for best absorption and don’t care for ethanol, but I appreciate that it doesn’t contain MCT, for those whose intestines would be irritated by it. Have you tried D3 in a base of olive oil? I’m wondering if you would be less sensitive to that excipient? Haha! I take no offense. As a recovering perfectionist, I understand neuroticism well and besides, you’re Italian so I trust your judgment. Now, if you try schooling me on butter, those are fighting words, mister. JK I bring my people shame—I don’t eat butter. Mayo is my dad’s condiment of choice for sandwiches and he doesn’t like the coconut-based one, due to it solidifying in the fridge and needing to take it out in advance to soften it before use, which he doesn’t have the patience for, so I figure the Graza is a good compromise. What type of olive oil do you prefer? I get my dad the “fancy” made with 100% extra virgin olive oil. Is extra virgin not good? While growing up, my mum used mainly butter in her cooking and evoo in her baking—she did cake decorating and swore by oil for moist cakes—so that’s my only reference point.
  • Discussing pistol squats, concentric exercise, resting, and other forms of strength training.

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    alfredoolivasA
    @PrinceTrebata very ho behaviour not replying. Sorry. I stopped the back ones and still don’t do them( I am still catabolic! Not getting stronger in the gym! Back aches! Bone hurts!) despite getting more than enough protein. This is perfect btw. I am not trying to be anabolic, as that usually entails with some sort of fat growth or water retention from AAS. But that’s a different story more suited for the moggy chicken Currently have been and am doing high seat biking. If I recover (hopefully when I slowly ramp up the calories), and those issues go away, I’ll throw in the stretches and stretching machine. If I find a sustainable routine with time.
  • Dental question - Dr Ellie's Protocol

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    @jd_au I’ve watched her. Gut health is a huge part of oral health. She never mentions gut health. So with that- im skeptical of her protocol. But Ray is about Perceive Think Act. You can always try and modify as needed. Ray always experimented on himself. Just be prudent.
  • B1 thiamine for memory

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    Does anyone know what type of B1 Peat recommended? HCL? He never seemed to specify.
  • There might be therapeutic benefits in increasing fat intake

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    @LucH said: I can develop if interested how I would manage. Yes I would be interested in your methodology...
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  • The Mysterious Case of Pufa Depletion

    pufa diet thyroid dnp
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    TexugoDoMelT
    @hcwilliams Ray recommended the slow approach. -Remove PUFAs from the diet -More carbs -Antilipolytics (B3, aspirin, etc.) -Other “saturators” (such as policosanol and perhaps the ones you mentioned) -T3 supplementation(which has a PUFA-depleting effect when you've already limited them in your diet) That way, you limited the PUFAs’ access to the mitochondria and could safely eliminate them through glucuronidation. The effect is the same as what I mentioned in one of my earlier comments. If a sample were taken, the tissues would have very low levels of PUFAs, so you could eliminate them in a controlled manner, which isn’t the case for most peaters, since losing fat isn’t really a concern for most of them. In that case, every time too much stored PUFAs were released, the situation would change. If someone has the patience to wait 4–6 years for that, I don't see why they shouldn't plan for gradual weight loss as well. You can easily lose 10–20 kg over that time without even worrying about it. Peaters madness
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    I bet you could get away with taking 1/10th of the recommended dose due to first pass bypass, similar to skin absorption id prefer skin application if the solubility wasn't so ass and required me tasting and smelling like dmso for hours
  • I never have a good sleep and I'm always tired during the day.

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    HEAR ME OUT AND OBEY. Gaze at the sky, the great blue sky. Never directly at the sun. Everyday. Initially it will strain your eyes. Dont overstress. Just do what you can do. It will regulate your biologic watch. Make your bedroom extremelly dark to get a restful sleep. Look for ways to rest and regenerate your eyes. Ex. Eating raw egg yolk makes my eyes less prone to light sensibility, eating salted raw carrot with little lemon improves guts health and lowers estrogen - great cause of eye health decay. "I will stay behind, to gaze at the sun. The sun is a wondrous body. Like a magnificent father! If only I could be so grossly incandescent!"
  • Ray Peat HATED manganese

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    @user1 To some degree, yes. The Orsense device measures hemoglobin via light sensors. When I have donated blood over the past 2 years, they have used this device to measure hemoglobin- https://www.youtube.com/watch?v=PkeD7ybugHk I don't know if you could tell much difference with the naked eye. Plus, if you see blood outside the body, it's going to be reacting with oxygen and clotting, both things that would make it darker and thicker. Also, while people with higher iron levels tend to have higher hemoglobin, it's a very rough guideline. People with certain types of anemias can even have high iron levels. And for most people, you can raise hemoglobin levels with a B complex. During de-ironing, I actually got hemoglobin to go up while ferritin was going down by using a B Complex and/or an iron free multivitamin with the same B Vitamins.
  • Silicon the dietary nutrient

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    LucHL
    @Hearthfire said: I think you get more silica/extract overall with ... What about the size of the silicon molecule to reach the cell, as if any " bio extract" from water, vegetable or bread could reach the target / the cell, at the same level !? No matter the state of your metabolism (> 55 yrs)
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    @sunsunsun said: apparently detection of viruses in ill people isnt really proof that this is causing the illness This is obviously true. You can observe all sorts of things on a sick person that probably have no effect on them being sick, like dandruff. Many sick people have dandruff, but is dandruff the cause of the illness? Even just sticking with microbes, it's obviously true. Both sick and healthy people have a gut biome, which is made up of several strains of bacteria, numbering into the trillions of individual cells. In any so called "viral" disease, the presence of trillions of bacteria in the gut are overlooked as a factor. Truthfully, even other "viruses" are neglected to be tested. As an example, when people were tested for the "Novel Corona Virus," they neglected to test for all the previous "Corona Viruses," as well as other "common cold and flu viruses." If you ran tests for 20 different "viruses" that are thought to cause cold and flu symptoms (and therefore, "Covid Symptoms" because there is a 100% overlap), and 7 came back positive, how could you claim that any single "virus" was responsible for the symptoms? It's actually worse than that, because EVERY "virus detection" test is actually a surrogate test. There is no way to directly test for ANY virus, not for the general public or in scientific studies. If there is no way to directly detect any virus, then how can you possibly create a remotely accurate surrogate test? Simply stated, there isn't, and in the case of Covid, the hundreds of millions of "asymptomatic patients" prove that. some people say covid isnt real, there's that tanksnowgood guy on rpf who constantly goes on about how there no such thing. when I got wuflu (I assume thats what it was) I got obscenely ill for 2 weeks and also experienced the weird sewage smell stuff and various other similar weird symptoms a lot of people describe. The claim that "covid isn't real" is really a claim that the alleged "Novel Corona Virus," aka SARS-Cov2 doesn't exist. Obviously, the symptoms people got when they got so called Covid are real. Things like coughing and fever can be easily observed in the real world. But the symptoms don't prove the cause. If you read the "Covid Isolation Reports," you can see that in truth, they never "isolated" anything. They took a sample from a sick person, along with all the potential other microbes, added to it a mixture of monkey kidney cells (aka, Vero cells), some antibiotics, some digestive enzymes like trypsin, Fetal Bovine serum, and cultured it in a medium that didn't provide adequate nutrients for cell survival. Then, when the cells showed signs of dying or breaking apart, they claimed that it was the result of an alleged "virus," and dismissed concepts like cell starvation, or the cell being poisoned by the antibiotics, or being ripped apart from the digestive enzymes. Since these "isolation tests" are the ONLY proof of a virus, the conclusion a lot of people have drawn is that SARS-Cov2 (and likely all other viruses) don't actually exist.
  • Anyone here diagnosed with POTS/MCAS/Dysautonomia?

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    LucHL
    @jd_au said: Keep it simple folks. Still fine for you. However, when taking HD B1, there is a protocol to follow. In short, there is interaction between several vitamins and trace elements. I then asked AI to help clarify the why and the how for other readers. AI says, as if LucH were speaking to JD: Glad it has lasted for you, JD! That is fantastic personal success, and it actually makes perfect sense given the specific combination you used. When you take thyroid hormone alongside thiamine, you are directly addressing the systemic metabolic bottleneck. In the bioenergetic framework Dr. Ray Peat talked about, low thyroid impairs the liver's ability to clear excess estrogen. High estrogen triggers nitric oxide, which over-relaxes (smoothes out) the blood vessels in the lower extremities, causing blood to pool and forcing the heart to beat faster to compensate (POTS). By taking thyroid and thiamine together, you restored cellular energy and vascular tone simultaneously, which is why your results have been so stable. However, for other readers looking to replicate this, it is crucial to understand why standalone High-Dose Thiamine (HD B1) protocols usually require cofactors. Skipping them can cause issues for the average person due to several factors: Magnesium is Mandatory: Thiamine cannot be converted into its active, usable form (thiamine pyrophosphate) without magnesium. Mega-dosing B1 alone rapidly depletes magnesium stores. This frequently triggers severe muscle cramps, anxiety, and heart palpitations, which people often mistake for a worsening of their POTS. The "Paradoxical Reaction": High doses of B1 can kickstart dormant mitochondrial pathways so suddenly that it causes a temporary, severe flare-up of autonomic symptoms. Adequate magnesium, potassium, and baseline nutrition help buffer this transition and prevent a metabolic shock. B-Complex Imbalance: Flooding the system with massive doses of a single B vitamin can eventually create a functional deficiency in other B vitamins (like B2 and B3) that share the same cellular energy pathways. In short, JD's success is a great example of the bioenergetic approach working perfectly because the underlying thyroid and estrogen pieces were addressed. But for most people starting a high-dose thiamine protocol on its own, skipping cofactors like magnesium is a frequent cause of metabolic stalls or severe symptom regressions. Keep it simple, but keep the underlying biochemistry in mind!
  • 5aDHP group buy - new source.

    5adhp
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    jamezb46J
    @Mauritio What effects did you notice from 3a-DHP and at what doses?
  • what compounds//chemicals do you think peat neglected?

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    @ThinPicking lol. 80s metal and 30s science
  • Diclofenac gel to regrow hair on bald head and beard

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    @Mossy areata though
  • Anything peaty for getting paperwork done?

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    MossyM
    @sunsunsun Indeed! Hence my need to call out my generalizing.
  • Epitestosterone, premature balding, and "male PCOS"

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    Has anyone tried well cooked mushrooms? There are many people reporting that it shifts the test/e2 ratio incredibly favorably, (better even than AIs). I hate to keep spamming Hans’ substack, but he’s run bloodwork pre-post mushroom experiments, and shown test/e2 rations above 20:1, (might have been 30:1 I don’t remember). Myself personally, (no bloodwork) but since I’ve added 3oz of well cooked mushrooms to each meal, I’ve seen nothing but improvement, (less puffy, zero constipation, reduction in inflammation, better mood etc).
  • Low Glutamate Diet

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    @user1 Thanks - I intuitively like maple syrup (manganese source). I eat it quite often in milk, and it may be somewhat calming. I like it.
  • how much liver do yall eat a week?

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    MossyM
    @hcwilliams Funny you mention this. I just fried some in a pan last night, and then covered it with sage butter, and it was considerably better than without it. Sage butter takes roughly 5 minutes to make, and adds quite a bit of flavor. There are variations of sage butter recipes. Some are as simple as butter and sage, I used butter, sage, salt, and garlic power. If I had more time, I would've used minced garlic. P.S. Maybe most important of all, I soaked it in milk hours before cooking.
  • intresting chems source bounty

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    MauritioM
    @lobotomize said: Etifoxine Can be bought at BG Pharmaceuticals