Useful info for other readers to optimize weight (prevention)
Sweeteners and their impact on the microbiota + possible weight gain
Dr Philippe Veroli – SCE 10/23
Poison for your "good" gut bacteria
Most sweeteners pass through the digestive tract undigested and therefore arrive unaltered in contact with the intestinal flora, on which they have a direct impact.
The population of beneficial bacteria decreased, while that of eleven opportunistic bacterial genera increased. In addition, Butyrivibrio bacteria, associated with blood sugar control, were less abundant! ( 8 )
Artificial Sweeteners Help You… Gain Weight
Studies show that consumers of so-called diet drinks also have an increased risk of obesity (9). In fact, their risk of premature death is similar to those who consume sugary drinks (10)! A recent American study (11) even showed that the combined consumption of a sweetener (sucralose) and sucrose significantly disrupts carbohydrate metabolism and causes a chronic increase in blood glucose and insulin levels, which is not the case with the consumption of sucralose or sucrose alone. However, diet products are always consumed with other sources of sugar (bread, fries, pastries), which explains why products containing sweeteners can contribute to excess weight gain. This disruption is very rapid, as it was observed after consuming the sweetener only seven times over a two-week period. Furthermore, the absence of calories prevents satiety and increases sugar cravings. There is therefore no reason to consume light industrial products, neither for body weight management nor for general health.
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Sweeteners manipulate the brain
Normally, the brain's reward system is activated when it receives sugar. With sweeteners, this system is disrupted: the brain no longer receives its usual dose of sugar, and the craving for sugar is increased, leading to snacking, preferably on fatty and sweet foods, to compensate for the disappointment registered by the neurons. We have seen that aspartame consumption leads to the formation of phenylalanine, aspartic acid, and methanol. These substances enter the brain and can inhibit the synthesis and release of several neurotransmitters (dopamine, norepinephrine, and serotonin), which normally regulate brain neurological activity (16). Furthermore, aspartame alters the expression of genes regulating the excitation-inhibition balance in the amygdala, a brain region that regulates anxiety and fear.
Excerpt from this article:
Prise de poids, diabète : les substituts du sucre sont-ils tous cancérigènes ? (Weight gain, diabetes: are all sugar substitutes carcinogenic?)
Dr Philippe Veroli – SCE 10/23
https://mirzoune-ciboulette.forumactif.org/t1998-microbiote-info-diverse#29338
Sources & References
8. Dorin Harpaz D, Yeo LP, Cecchini F, et al. Measuring Artificial Sweeteners Toxicity Using a Bioluminescent Bacterial Panel. Molecules 2018, 23(10), 2454. doi.org/10.3390/molecules23102454
9. Fowler SP et coll. Fueling the obesity epidemic? Artificially sweetened beverage use and long-term weight gain. Obesity 2008; 16: 1894-900.
10. Mullee A et coll. Association between soft drink consumption and mortality in 10 European countries. JAMA Intern. Med. 2019; e192478.
11. Dalenberg JR et coll. Short-term consumption of sucralose with, but not without, carbohydrate impairs neural and metabolic sensitivity to sugar in humans. Cell Metab. 2020; 31: 493-502.
16. Choudhary AK, Lee YY. Neurophysiological symptoms and aspartame: What is the connection?. Nutritional neuroscience, 2018, vol. 21, no 5, p. 306-316.
