@Ilias-Ant Do you take any type of thyroid supplement? I can’t say for sure what’s going on, but if you are unable to tolerate sugar it is unlikely that your metabolism is thriving. Whatever kind of infection you have is likely impairing your metabolism, while also being a symptom of low metabolism. Someone with a high metabolic rate is not very susceptible to bacterial or fungal infection. In addition to thyroid supplementation, eating the carrot salad daily would probably beneficial.

@BeamsOfEnergy sorry I made a mistake it was meant to say acetazolamide and aspirin.

@winters2 said in Tocotrienols?: Do any of you take it? Isn’t it anti-peat, I’ve read that it suppresses cholesterol (same mechanism as statins) Chris Masterjohn knows a lot on cholesterol and takes / took 20-25 mg suppl a day to target what he wanted. Make a difference between RDA and pharmacological effects. RP has classified tocos as prometabolic (estrogen-antagonist when in excess) provided you take some points into account. If you're talking only about tocotrienols, I won't take them alone, except if in cure to target inflammation and optimize wealthy membrane. Only in cure then. Not at the same meal as vitamin K or other quinones. Useful links Assuming a typical intake of dietary PUFA, a vitamin E requirement ranging from 12 to 20 mg of RRR- -tocopherol/d can be calculated. The average westerner would need "only" 12-20 mg of natural vitamin E per day. The previous RDA has been changed since a majority of people were deficient. DOI:10.1017/S000711451500272X Vitamin E function and requirements in relation to PUFA. => Adjusting Vitamin E Needs with Unsaturated Oil Intake More info on Vit E (translator needed, in French): https://mirzoune-ciboulette.forumactif.org/t30-vitamine-e-plus-qu-une-vitamine#60 Excerpt 1: Most studies show a beginning of preventive efficiency at doses of 100 IU /d in degenerative diseases. Braking of oxidative stress which is underlying the phenomena of senescence and the appearance of all degenerative pathologies: cardiovascular, cancers, osteoarthritis, osteoporosis, presbyacousis, cataract, macular degeneration, Parkinson and Alzheimer's diseases, etc. Excerpt 2: Optimal contribution, without pathology, if under 40 years old: 100 IU per day. Contribution in case of supplementation in polyunsaturated fatty acids 100 IU per gram of EPA. - Therapeutic contribution: 400 - 500 IU every 5 days. Mg/ UI conversion: 100 mg = 150 IU. Personally, it’s 400 UI mixed toco every 3 days (+/ twice a week). 3x if inflammation. Note: High dose Vit K can interfere with Vit E metabolism. Not at the same time. Remind: Too much of a good thing is bad. Never take only one kind toco on a usual base. 2 tocos are required (functions are different).

@pittybitty My symptoms are consistent every day, bloating never really goes away, sometimes is a bit better, sometime a bit worse. I probably have candida overgrowth as well. My doc has ordered a lactulose breath test at the hospital, but I don’t feel comfortable to fast that long, so I would prefer to pay cash for a at home breath test for SIBO, but wondering if testing is worth or reliable at all to detect SIBO

Peat actually spoke out against limiting sugar in regards to Candida. I'm paraphrasing his arguments: Yes, Candida can ferment sugars into ethanol, however small amounts of ethanol is benign, and if you starve them of sugar the Candida will spread and attack your cells. And Duboe showed that if you starve these yeasts that are just happily making some ethanol out of the sugar, when they don't get sugar, they start... sending out pseudopods, or pseudohyphae, I think he calls them, which are invasive filaments that will sink into the intestine looking for sugar. And that's the point at which they can actually travel through your intestine and get into your systemic tissues looking for more glucose. So really... having sugar in your diet, if you have a fair infestation of yeast, for some reason, in your intestine, sugar is a defensive means while you're trying to figure out how to get rid of the yeast, which carrots will usually do fairly quickly. So essentially you want a high sugar diet to keep the yeast happy and the carrot salad to get rid of it while it is happy.

My pleasure, @GRay.

@LucH thank you brother. I really appreciate the assistance

@pittybitty said in Serotonergic slumps at night: Are you sure? Make a google search with: blocking noradrenaline led to fine dreams

@Milk-Destroyer I wonder if you had taken an antibiotic close to the time you took citric acid or citric acid-containing substance. I'm not sure which antibiotic I took at that time, whether it's erithromycin or tetracycline, but it's one which would cause bacteria into cell wall deficient bacteria, and in combination with citric acid, would lead to growth of microbes closer to fungal forms. But it made me very sick and I had to use my own protocol of Carbogen and turpentine and artemisia annual tincture to counter it. It was successful but it was luck that this protocol worked. But at that time, I didn't want to check into an ER because a worse outcome would be likely during the COVID hoaxing years.

thanks. I am listening to it now (It is raining). Here are the timestamps: 00:00 Intro 02:12 What Is Roger Aiming to Accomplish? 03:13 The 8 Pillars of Health 08:58 Story of Henry: A Fungal Lung Disease Patient 20:25 Why Our Mitochondria Need Sunlight 27:31 Sunlight and Viruses: Impact on COVID-19 29:45 Vitamin D and Lower Risk in COVID Patients 33:40 Benefits of Using Infrared Light Devices 47:35 Could More Sunlight Help You Live Longer? 51:05 Does the Sun Really Cause Melanoma? 54:22 Are Humans Meant to Live Outside? 57:16 Is It Worth Wearing an Infrared Light Mask? 59:16 How to Get Infrared Light on a Cloudy Day 01:07:59 Optimal Time of Day to Get Sunlight 01:09:19 Circadian Rhythm and Light Exposure 01:11:13 Benefits of SAD Light Therapy 01:12:47 Can Looking Through a Window Help Circadian Rhythm? 01:14:56 Why Should We Avoid Bright Screens at Night? 01:17:16 Should the Bedroom Be Completely Dark at Night? 01:19:08 Do Vitamin D Supplements Work? 01:20:59 Possible Consequences of Vitamin D Overdose 01:21:47 The Role of Vitamin D in the Body 01:23:45 Do Cravings Signal Nutrient Deficiencies? 01:25:20 Water’s Role in the Body 01:27:05 Interferons and the Innate Immune System 01:32:37 Importance of Hydration for Fighting Infections 01:34:20 Should We Use Hot and Cold Therapy Together? 01:35:55 Impact of Tree Aromas on Immunity 01:38:29 Do Indoor CO₂ Levels Matter? 01:39:15 How Can We Optimize Indoor Air Quality? 01:40:22 Faith as a Way to Deal With Stress and Anxiety 01:42:27 Conditional vs. Unconditional Forgiveness and Stress 01:45:40 Are People Who Believe in God Generally Healthier? 01:47:19 Roger’s Experience Witnessing Death 01:48:59 A Miraculous Story: Anoxic Brain Injury Recovery 01:59:02 Should Hospital Patients Be Taken Outside? 01:59:42 Are Melatonin Supplements Good for Sleep? 02:00:30 Side Effects of Melatonin Supplements

@alex155 said in Serotonin question: for those who are afraid of tryptophan and serotonin, this study about B. subtilis will be interesting, what bacteria should be avoided, but I assure you that you won't even be able to take a shit without serotonin... and for now I will continue to experiment on myself B.subtilis has shown to be capable of secreting polymyxin, difficidin, subtilin, and mycobacillin. [image: 1753998005826-20210426_190216.jpg] https://microchemlab.com/microorganisms/bacillus-subtilis/ thus reducing overall unwanted bacteria.

@lobotomize-me said in need advice: taurine I'd stop taking taurine, but not abruptly, every other day. Taurine is used for making bile. We want to avoid stagnation. Afterwards cut the dose to max 500 mg, once a day. And see how you react (adapt the posology). Note that 10 % fat is not enough, if you want to avoid problems with hormones and thermoregulation. I'd target 20% fat. useful info: Taurine plays a crucial role in bile production by acting as a substrate for the formation of bile salts. These bile salts, formed by conjugating bile acids with taurine or glycine, are essential for emulsifying fats and aiding in their digestion and absorption in the small intestine. The liver synthesizes bile acids, which are then conjugated with taurine and glycine, and stored in the gallbladder. Upon ingestion of fatty foods, these bile salts are released into the intestine, where they help break down fats.

I think I got an answer after thinking and sleeping and thinking about this for a long, long time. I could not put the difference between the alpha isomer and the gamma isomer in a context that is practical. Saying alpha is nucleophilic and gamma is electrophilic does not make me know which really to take. So I end up taking one over the other or both of them, just so I am safely protected whatever that means. But that just means I'm stumbling in the dark and no expert can ever give me an explanation I can really use. Then it hit me. And I had to check with my Delphi Ray Peats AI to see if my 'more practical' explanation makes more sense. And he agreed with me. So here it is. Boiled down and extracted of its essence, alpha-tocopherol based tocopherols are more useful when taken when you are eating out and you know you will be eating an unavoidable amount of PUFAs which always accompanied foods served, especially in popular restos where taste is paramount and chefs are paid for flavor and not for health (but of course as who goes to healthful restos but vegans and is veganism even that healthful but we can agree the flavor is zero). So, the bottom line is use it when you eat where you know you'll be eating a lot of PUFAs. Hopefully that won't be the case often, and doesn't give you an excuse to eat out too often and thinking the alpha tocopherol-heavy vitamin E is an amulet to ward off the lipid peroxidation devil. In short, it is taken to keep the lipid peroxidation from getting atarted. OTOH, gamma-tocopherol is meant to be taken for keeping the oxidized cholesterol in the plaque lining our blood vessels from undergoing further oxidation. Oxidized cholesterol, as Ray Peat clarified with me, is not all fully oxidized. It continues to oxidize as plaque. I think it should be called continually oxidizing cholesterol to be more accurate and to be less misleading. Gamma to opherol then is useful for those of us who have a past history of taking PUFAs and which have come to be part of our plaque as continually oxidizing cholesterol. I've stopped taking PUFAs at home for 9 years already, but I have a PUFA past, so I would be big on taking gamma-tocopherol-heavy mixed tocopherols for my vitamin E supplementation. I suspect the lipid peroxidation it carries out requires my body to use albumin (as well as other antioxidants such as uric acid) as an antioxidant to counter the oxidative stress caused by lipid peroxidation. As albumin gets oxidized and gets excreted thru urine (characterized by urine foam or froth), it depletes my serum albumin and this lowers the blood volume (as albumin attracts sodium and sodium attracts more water) and this is a main cause of my high blood pressure. Anyway, to keep this topic from devolving, suffice it to remember gamma-tocopherol is needed for lipid peroxidation already begun and continuing in the plaque of our blood vessels. But when I eat out, or when I am on food trips on travels, I'll bring a d-alpha tocopherol-heavy vitamin E with me.

I think people have been pretty civil here without any heavy-handed enforcement from the moderators. The main things are no violent threats, no spam, no AI slop. You can mute and block people who offend you, or even better, gently ridicule them.

@DavidPS said in Gut Bifidobacteria Populations in Human Health and Aging: Bifidobacteria is considered a keystone ins\testial species and its propulations appear to decline with age. [image: 1718205663746-aeecb699-aa85-4e9f-8f24-d37342dd1b1e-image.png] Gut Bifidobacteria Populations in Human Health and Aging I have been supplementing with the probiotic Bifidobacterium Infantis in the hope of restoring more youthful levels of the bacteria. I have not tested my levels of Bifidobacterium Infantis so I do not know if it works. The thread has some information about it helping with digestion.

@pittybitty Mixed tocopherols, the cleanest supplement you can find, 400 IU as needed, is what I'm doing.