Noticeable info to help damping unbalance microbiome
Iodine exerts antioxidative, antimicrobial, immunomodulatory, and molecular regulatory effects. Iodine alters the proportion of pathogenic and beneficial bacteria to restore the gut microbiome and reduce insulin resistance, obesity, and metabolic syndrome parameters.
Iodine also reduces inflammation by lowering oxidative and endoplasmic reticulum stress caused by free radicals such as reactive oxygen species (ROS).
The mineral acts on type 2 deiodinase (D2) receptors that convert T4 to biologically active T3 to improve weight management and adaptive thermogenesis. (1)
Iodine also interacts with peroxisome proliferator-activated receptor-γ (PPARγ) receptors to enhance adipocyte differentiation, fatty acid uptake, and glucose metabolism …
Source: The correlation between iodine and metabolism: a review.
2024 | https://doi.org/10.3389/fnut.2024.1346452
Reference 1:
Thyroid hormone signaling: The type II (D2) deiodinase catalyzes T4-to-T3 conversion
Role of the type 2 iodothyronine deiodinase (D2) in the control of thyroid hormone signaling
10.1016/j.bbagen.2012.08.019
Comment (LucH):
Mind the way you use iodine supplement.
Slow progression (staples) to avoid Wolff-Chaikoff effect.
Info on why and how to manage with iodine (we need 2 kinds: Molecular iodine (I₂) and iodide potassium (IK).
https://bioenergetic.forum/topic/3962/iodine-as-a-game-changer/6
Excerpt:
*) Which kind iodine is used and where?
The thyroid and skin use almost only KI type iodides, or potassium iodide, the form of supplementation found for example in iodized table salt. But the breast, prostate, ovary and brain need molecular iodine type I2. The kidney, spleen, liver, blood, salivary glands, intestines and muscles necessarily all have a joint contribution in both forms (56). The fight against cancer, probably also (57). And all these organs are abandoned to their sad deiodized fate...
Woman breast needs more than what is allowed through food, even when eating fish twice a week and drinking half a liter milk. And by the way – for men aged > 65, prostate requires I2 too. Breast and prostate need I2. But the average iodine intake will not be high enough to reach another organ than the thyroid…