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  • Scientific papers, books, blog posts. Discussion of whatever you find interesting and notable.

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    U
    Increased Androgens: A pilot study on male volunteers (1 g/day for 1 month) found that DCI administration was associated with a +23.4% increase in testosterone and a +13.8% increase in dehydroepiandrosterone (DHEA). Reduced Estrogens: In the same study, DCI significantly reduced estrone levels (-85.0%) and reduced estradiol levels (-14.4%). Androgen Precursors: In addition to DHEA, other androgen precursors like epiandrosterone also increased (+39%). Aromatase Inhibition: DCI is believed to act as an aromatase down-modulator (inhibitor), reducing the conversion of androgens (like testosterone) into estrogens (like estradiol and estrone). D-chiro-inositol (DCI) acts to mimic insulin and also stimulate PDHP (pyruvate dehydrogenase phosphatase), which in turn dephosphorylates and activates PDH (pyruvate dehydrogenase). Acute Post-Meal Reduction: Clinical studies have shown that DCI, often in combination with myo-inositol, can acutely reduce the insulin spike that typically follows glucose or carb intake. Improved Sensitivity: By enhancing the activation of the insulin receptor pathway (specifically IRS2 and GLUT4), DCI allows the insulin already present in your system to work more effectively. Sparing Effect: Because DCI mimics certain insulin actions—like promoting glucose uptake into muscle and fat—it can have an insulin-sparing effect, meaning the body achieves the same blood sugar control with lower systemic insulin levels. taking D-chiro-inositol (DCI) or similar mimetics with carbohydrates can reduce the body's overall need for insulin by improving how cells process glucose.

  • Websites, newsletters, articles, podcasts, interviews, explainers, books, and other resources that relate to the work of Dr. Raymond Peat.

    62 Topics
    702 Posts
    C
    Cancer Treatments – from Research to Application MCS Foundations for Life, In memory of my dear wife Mihaela Catalina Stanciu https://www.cancertreatmentsresearch.com/ https://jeffreydachmd.com/cancer-articles/

  • Do you have a question? You can post it here, but you will only receive unqualified personal opinions and NOT medical advice in any shape or form. If something seems like medical advice but it's posted in this category, it's actually a personal opinion.

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    alfredoolivasA
    @engineer Drop everything

  • From medical devices to supplements. Red lights, CO2 tanks, large trash bags, kuinone, and more.

    383 Topics
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    daposeD
    @engineer it really depends on what you ordered and what solvent you selected. Not all have options but some do. Which product are you referring to? Georgi will randomly swap out ingredients and or solvents on occasion. Not too often but enough times where I pay close attention to what he is selling “in stock” as an example I order his magnoil which is always a specific form of magnesium in dmso oil. But one time I got the product and I had to squeeze so hard my eyeballs were going to pop out of my head to get one drop. After a week of tripling my grip strength I looked it up and he was out of the normal for of magnesium and put the fill mag in a deferent solvent. I threw the dumb one away and waited for dmso to show up on the website. I’ve seen varying bottle types over the years too.

  • Recipes, food, meal prep, brands. Discuss them all here.

    233 Topics
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    sunsunsunS
    also posting here, someone on rpf posted about embryo rice, this is something I am looking into, apparently, and im not sure, it is usually brown rice , and in the package they will also put in the embryo from the processing of other rice into white rice to boost the nutrients. I might be wrong, it might also be brown rice that is only partially processed so that it removes something but retains the embryo, im not sure, it's sold at asian supermarkets and I haven't tried it yet.

  • Discussing pistol squats, concentric exercise, resting, and other forms of strength training.

    85 Topics
    1k Posts
    alfredoolivasA
    @sunsunsun https://www.youtube.com/watch?v=7f25pFhuAaY
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  • wolfyW

    How do you get rid of hay fever?

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    Try checking some of the excipients in any supplements you are taking or perhaps there is something you are eating that may be causing intestinal irritation which can lead to allergic symptoms.
  • wolfyW

    Resting heart rate dropped to 55-60 after peating.

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    wolfyW
    @cs3000 well, I'm almost never cold anymore, and I've been seriously exercising for 8 years now, so I guess I have a big heart, idk I've never measured my heart, not sure how I would.
  • ?

    Nicole Shanahan (VP pick/RFK Jr Independent presidential candidate) talks Bioenergetics, Science, Tech, AI

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  • M

    Are There Any Serious Side Effects Associated With Varenicline? | Dealonpill

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  • the MOUSET

    thoughts this article Metabolic Endotoxemia: The Link Between the Chronic Diseases and the Saturated Fats You Want to Avoid

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    @insufferable said in thoughts this article Metabolic Endotoxemia: The Link Between the Chronic Diseases and the Saturated Fats You Want to Avoid: I remember RPF posts that explained this by saying that saturated fat was actually clearing the endotoxin away or something and was actually good for endotoxin reduction. I don't know. I do know that coconut oil always makes my digestion great. Me too. Ray Peat was a big advocate for coconut oil and saturated fat, but a lower fat diet overall. I watched my father die young of heart disease after following the bad advice of doctors to only eat unsaturated fats after he had a heart attack at an early age. This study was entirely too technical for me, but... [image: 1712378243998-a14ff105-d38f-43f1-a6c7-bb491ef370c9-image.png] https://x.com/ChrisMasterjohn/status/1774506746788065456
  • b4ndsup.mannyB

    Can I ingest topical E oil orally?

    vitamin e
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  • T

    Any help with vaginismus?

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    @TurkishPeater roleplay as Gorbachev and the berlin wall. Threaten to nuke that pussy from orbit if she don't open up. Play subliminals of wet fish slapping against marble tables on repeat whilst giving her neck massages. Trust
  • I

    Charlie abandones Ray Peat for Naturopathic "Doctor" Garrett Smith

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    @Peatly Yes, I read that conversation. I think it was the salesman in him. He obviously is profit-driven and was likely looking to develop a 'better' product. Edit: I'm not a Mercola stan, but I think he is just a flawed perhaps egotistical individual with a profit-driven model of 'success'.
  • E

    My #1 hobby is watching mike fave (fellow peater) debunk these mainstream health gurus (glucose goddess)

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    @Energetics He does a great job.
  • the MOUSET

    my recent subhuman bloodwork for recurring nausea/anxiety

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    @the-MOUSE https://bioenergetic.forum/topic/1630/soil-health-and-its-relations-to-plant-animal-and-consequently-human-health/10 Have a look at the second post for ideas about gut health too. Not exactly the same type of approach but can still work.
  • cs3000C

    This topic is deleted!

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  • ILikeToGetPeatOnI

    Bioenergetic Guide to Pregnancy?

    pregnenolone progesterone postpartum
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    JulofEnochJ
    @Sippy They were full of excipients if I recall correctly. So many things are these days. Do you know of any resources for interpreting the results and deciding how to correct imbalances? Regarding interpretation, I am no expert myself so I've relied on others knowledgeable to help me. I cannot vouch for everything this guy says but his videos on HTMA have been useful for me. If you want a real expert with a focus on mineral balancing, fertility, etc. then Andra is someone who you should consider speaking with. Her Twitter is a good resource for free knowledge. Andra is no stranger to Peat and the Bioenergetic community.
  • wolfyW

    How do I get rid of ring worm?

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    @wolfy Just a few drops of liquid iodine on to the affected area.
  • Hando-JinH

    Taurine extends life up to 12%

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    @DavidPS It doesn’t have to be either or. You are right CoQ10 could have been studied and it was Coenzyme Q10 as Treatment for Long Term COVID-19 High-dose coenzyme Q10 therapy versus placebo in patients with post COVID-19 condition: a randomized, phase 2, crossover trial Clearly taurine helps in a way that q10 does not Functional Role of Taurine in Aging and Cardiovascular Health: An Updated Overview From the article "The beneficial effects of taurine on Ca2+ and sodium (Na+) handling [89,90,99,100,101,102,103], myocardial energetics [104,105], and cellular signaling pathways (including glucose transport, 3-phosphoinositide-dependent protein kinase-1, AKT, sirtuin 1 (SIRT1), FOXO3, p38, NFkappaB, and others) [106,107,108,109,110,111,112,113,114,115,116,117,118,119,120,121] are thought to underlie its major cardioprotective effects. Other mechanisms include the promotion of natriuresis and diuresis, most likely via an osmoregulatory activity in the kidney, a regulation of vasopressin release, and a modulation of the atrial natriuretic factor secretion [122,123,124,125]. In addition, taurine has been shown to attenuate the actions of angiotensin II on its downstream signaling pathways, on Ca2+ transport, and on protein synthesis [113]." I came across this - so leaving it here too Angiotensin-Converting Enzyme 2: SARS-CoV-2 Receptor and Regulator of the Renin-Angiotensin System
  • HeightOptimizedH

    Caffeine is BAD for GROWING TALLER

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    HeightOptimizedH
    @izkrov ? That is not associated with what I’m talking about. That study is not even associated with what im talking about either I agree with you that the difference isn’t huge. Although based upon the 2 responses you have sent me you did not read all the articles fully, then understood what they were talking about. The writing clearly states bone growth pauses because of caffiene.
  • TopicalsOnBallsT

    Topical Solutions on scalp for hair regrowth

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    ChudC
    @TopicalsOnBalls said in Topical Solutions on scalp for hair regrowth: interesting, you’re not concerned of the downstream effects of minoxidil? im making sure to apply minoxidil away from the times i dermastamp, i wait 24 hours, the systemic aborbtion is very low from what ive read. i am a little concerned about downstream effects, i think haidut posted on RPF how some people are getting PFS from topical minox which is pretty scary. https://www.askapatient.com/viewrating.asp?drug=20834&name=ROGAINE+EXTRA+STRENGTH+(FOR+MEN) ive been on it for a few weeks now and my erections are fine and no sides so far. its by far the most effective pharmaceutical for hairloss and doesnt seem to mess with DHT so im taking the chance. @TopicalsOnBalls said in Topical Solutions on scalp for hair regrowth: Unique way to use coke, I’ve read about others getting glucose to the scalp by using a honey mask honey is too sticky and gets tangled in my hair. i filled a spray bottle with some coke and just spray it on my scalp and massage it in whenever i can remember, its just a convenient way to get some sugar on there. "Ray Peat: I've been thinking that with a concentrated glucose solution, you could probably activate hair growth just by keeping your scalp moistened with glucose."
  • HeightOptimizedH

    Mean foot length increased by nearly a half size after 3 hours of walking on a treadmill.

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    JulofEnochJ
    Study link Important to note that this is not a structural change. The post-exertion swelling of the feet is due to increased blood flow. If one were to walk for many hours, for many months, then you'd develop structural changes. Walking on a treadmill for three hours sounds like it sucks.
  • HeightOptimizedH

    DHT and its role in promoting GROWTH in HEIGHT

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  • wolfyW

    Is there a way to change my curly hair into straight

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    wolfyW
    @pittybitty I don't like curly hair, it doesn't suit my face and frizzes up really easily. It's more difficult to maintain. And people make fun of me for it.
  • the MOUSET

    do you need to get sterile small intestine first before going on raypeat?

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    SIBO can always cause unforeseen issues, but "transitioning" should be smooth. A good healthy diet wouldn't be that much different from a so called "normie diet." The biggest differences are what you're not eating. Processed foods for the most part. But more importantly seed oils, thickeners like guar gum, gellan gum, bean gum, arabic gum, xanthan gum, carrageenan, added phosphates like dicalcium phosphate, sodium phosphate, trisodium phosphate, phosphoric acid, etc. For many people citric acid will be a no go as well, also iron fortification. Vitamin fortification may cause issues with some people who are sensitive. Some people can tolerate whole milk but not low-fat milk (which is fortified). That's literally 95% of the work right there. Anything else is minuscule at best. And would more or less be "fine tuning" to your specific tolerances. Like, for example, some people don't respond to starch well, or grains. Some people can't handle dairy. Some do better with starch than fruit, etc.