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  • Scientific papers, books, blog posts. Discussion of whatever you find interesting and notable.

    543 Topics
    4k Posts
    LucHL
    @DavidPS said in Lipofuscin accumulation in aging and neurodegeneration: Dr. Peat has written about lipofuscin. Too many options (lazy). here I've got this info on my pC. *) How the Oils In Your Diet Are Aging Your Skin. Dr. Peat goes on to explain what this rancidity (oxidation process) does: "The free radicals produced in this process react with parts of cells, such as molecules of DNA and protein, and may become attached to those molecules, causing abnormalities of structure and function." https://raypeat.com/articles/articles/unsaturated-oils.shtml EGCG Inhibited Lipofuscin Formation Based on Intercepting Amyloidogenic β-Sheet-Rich Structure Conversion https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4816542/ "Lipofuscin (LF) is formed during lipid peroxidation and sugar glycosylation by carbonyl-amino crosslinks with biomacrolecules, and accumulates slowly within postmitotic cells. The environmental pollution, modern dietary culture and lifestyle changes have been found to be the major sources of reactive carbonyl compounds in vivo. Irreversible carbonyl-amino crosslinks induced by carbonyl stress are essentially toxiferous for aging-related functional losses in modern society. Results show that (-)-epigallocatechin gallate (EGCG), the main polyphenol in green tea, can neutralize the carbonyl-amino cross-linking reaction and inhibit LF formation, but the underlying mechanism is unknown."

  • Websites, newsletters, articles, podcasts, interviews, explainers, books, and other resources that relate to the work of Dr. Raymond Peat.

    61 Topics
    696 Posts
    yerragY
    @what-about-bob Thanks. I like the summary. How everything all fits in from theae great minds and put together by Ray Peat into more practical lifestyle applicable ideas. I am appreciating how I see myself on the "applied technology" end of their contributions as I incorporate these ideas into my attempt to be my own doctor as I attempt to improve my health. I have been unable for the past 24 years to lower my blood pressure without using prescription medication. But I am seeing the light at the end of this tunnel. It is a long process of learning and I don't give up. Thanks to recent developments in science and technology, I may be able to lower my blood pressure finally using ideas from Peat and his predecessors. What has been helpful is my use of AI as an efficient research assistant and aggregator of concepts and minute details that my own limited human mind can't recall easily and utilize readily.

  • Do you have a question? You can post it here, but you will only receive unqualified personal opinions and NOT medical advice in any shape or form. If something seems like medical advice but it's posted in this category, it's actually a personal opinion.

    1k Topics
    10k Posts
    S
    ^^^^what he said. He’s always taking about his labs and dropping some numbers, but I’ve never seen them posted, especially not in a comprehensive fashion. Maybe they’re behind a paywall, I don’t know.

  • From medical devices to supplements. Red lights, CO2 tanks, large trash bags, kuinone, and more.

    360 Topics
    3k Posts
    alfredoolivasA
    @engineer @engineer said in Separation in Pansterone bottle: Saw that, really interesting how 6 keto has had approximately 0 interest since that 50s study oh my, if what you're saying is true, then Georgi made a major oversight with how common precipitation seems to be judging by other reports on RPF. You are coming close to taking the Peat black pill. We welcome you

  • Recipes, food, meal prep, brands. Discuss them all here.

    226 Topics
    1k Posts
    alfredoolivasA
    @heyman said in Euphoric foods: äggost Does it taste like cream cheese?

  • Discussing pistol squats, concentric exercise, resting, and other forms of strength training.

    85 Topics
    1k Posts
    BioEclecticB
    @jamezb46 said in pre workout / intra / post workout: @BioEclectic Why do you think lactic acid produces DOMS? From what i had read at the old RPF forum, though i always hold open the possibility that i have either misconstrued or misremembered whatever i had read. Not sure if this applies but I do know it noticeably reduces work or shoe related foot soreness. Mag sulfate and Mag bicarbonate.
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  • T

    Any help with vaginismus?

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    H
    @TurkishPeater roleplay as Gorbachev and the berlin wall. Threaten to nuke that pussy from orbit if she don't open up. Play subliminals of wet fish slapping against marble tables on repeat whilst giving her neck massages. Trust
  • I

    Charlie abandones Ray Peat for Naturopathic "Doctor" Garrett Smith

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    ?
    @Peatly Yes, I read that conversation. I think it was the salesman in him. He obviously is profit-driven and was likely looking to develop a 'better' product. Edit: I'm not a Mercola stan, but I think he is just a flawed perhaps egotistical individual with a profit-driven model of 'success'.
  • E

    My #1 hobby is watching mike fave (fellow peater) debunk these mainstream health gurus (glucose goddess)

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    S
    @Energetics He does a great job.
  • the MOUSET

    my recent subhuman bloodwork for recurring nausea/anxiety

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    ?
    @the-MOUSE https://bioenergetic.forum/topic/1630/soil-health-and-its-relations-to-plant-animal-and-consequently-human-health/10 Have a look at the second post for ideas about gut health too. Not exactly the same type of approach but can still work.
  • cs3000C

    This topic is deleted!

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  • ILikeToGetPeatOnI

    Bioenergetic Guide to Pregnancy?

    pregnenolone progesterone postpartum
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    JulofEnochJ
    @Sippy They were full of excipients if I recall correctly. So many things are these days. Do you know of any resources for interpreting the results and deciding how to correct imbalances? Regarding interpretation, I am no expert myself so I've relied on others knowledgeable to help me. I cannot vouch for everything this guy says but his videos on HTMA have been useful for me. If you want a real expert with a focus on mineral balancing, fertility, etc. then Andra is someone who you should consider speaking with. Her Twitter is a good resource for free knowledge. Andra is no stranger to Peat and the Bioenergetic community.
  • wolfyW

    How do I get rid of ring worm?

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    K
    @wolfy Just a few drops of liquid iodine on to the affected area.
  • Hando-JinH

    Taurine extends life up to 12%

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    P
    @DavidPS It doesn’t have to be either or. You are right CoQ10 could have been studied and it was Coenzyme Q10 as Treatment for Long Term COVID-19 High-dose coenzyme Q10 therapy versus placebo in patients with post COVID-19 condition: a randomized, phase 2, crossover trial Clearly taurine helps in a way that q10 does not Functional Role of Taurine in Aging and Cardiovascular Health: An Updated Overview From the article "The beneficial effects of taurine on Ca2+ and sodium (Na+) handling [89,90,99,100,101,102,103], myocardial energetics [104,105], and cellular signaling pathways (including glucose transport, 3-phosphoinositide-dependent protein kinase-1, AKT, sirtuin 1 (SIRT1), FOXO3, p38, NFkappaB, and others) [106,107,108,109,110,111,112,113,114,115,116,117,118,119,120,121] are thought to underlie its major cardioprotective effects. Other mechanisms include the promotion of natriuresis and diuresis, most likely via an osmoregulatory activity in the kidney, a regulation of vasopressin release, and a modulation of the atrial natriuretic factor secretion [122,123,124,125]. In addition, taurine has been shown to attenuate the actions of angiotensin II on its downstream signaling pathways, on Ca2+ transport, and on protein synthesis [113]." I came across this - so leaving it here too Angiotensin-Converting Enzyme 2: SARS-CoV-2 Receptor and Regulator of the Renin-Angiotensin System
  • HeightOptimizedH

    Caffeine is BAD for GROWING TALLER

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    HeightOptimizedH
    @izkrov ? That is not associated with what I’m talking about. That study is not even associated with what im talking about either I agree with you that the difference isn’t huge. Although based upon the 2 responses you have sent me you did not read all the articles fully, then understood what they were talking about. The writing clearly states bone growth pauses because of caffiene.
  • TopicalsOnBallsT

    Topical Solutions on scalp for hair regrowth

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    ChudC
    @TopicalsOnBalls said in Topical Solutions on scalp for hair regrowth: interesting, you’re not concerned of the downstream effects of minoxidil? im making sure to apply minoxidil away from the times i dermastamp, i wait 24 hours, the systemic aborbtion is very low from what ive read. i am a little concerned about downstream effects, i think haidut posted on RPF how some people are getting PFS from topical minox which is pretty scary. https://www.askapatient.com/viewrating.asp?drug=20834&name=ROGAINE+EXTRA+STRENGTH+(FOR+MEN) ive been on it for a few weeks now and my erections are fine and no sides so far. its by far the most effective pharmaceutical for hairloss and doesnt seem to mess with DHT so im taking the chance. @TopicalsOnBalls said in Topical Solutions on scalp for hair regrowth: Unique way to use coke, I’ve read about others getting glucose to the scalp by using a honey mask honey is too sticky and gets tangled in my hair. i filled a spray bottle with some coke and just spray it on my scalp and massage it in whenever i can remember, its just a convenient way to get some sugar on there. "Ray Peat: I've been thinking that with a concentrated glucose solution, you could probably activate hair growth just by keeping your scalp moistened with glucose."
  • HeightOptimizedH

    Mean foot length increased by nearly a half size after 3 hours of walking on a treadmill.

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    JulofEnochJ
    Study link Important to note that this is not a structural change. The post-exertion swelling of the feet is due to increased blood flow. If one were to walk for many hours, for many months, then you'd develop structural changes. Walking on a treadmill for three hours sounds like it sucks.
  • HeightOptimizedH

    DHT and its role in promoting GROWTH in HEIGHT

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  • wolfyW

    Is there a way to change my curly hair into straight

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    wolfyW
    @pittybitty I don't like curly hair, it doesn't suit my face and frizzes up really easily. It's more difficult to maintain. And people make fun of me for it.
  • the MOUSET

    do you need to get sterile small intestine first before going on raypeat?

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    M
    SIBO can always cause unforeseen issues, but "transitioning" should be smooth. A good healthy diet wouldn't be that much different from a so called "normie diet." The biggest differences are what you're not eating. Processed foods for the most part. But more importantly seed oils, thickeners like guar gum, gellan gum, bean gum, arabic gum, xanthan gum, carrageenan, added phosphates like dicalcium phosphate, sodium phosphate, trisodium phosphate, phosphoric acid, etc. For many people citric acid will be a no go as well, also iron fortification. Vitamin fortification may cause issues with some people who are sensitive. Some people can tolerate whole milk but not low-fat milk (which is fortified). That's literally 95% of the work right there. Anything else is minuscule at best. And would more or less be "fine tuning" to your specific tolerances. Like, for example, some people don't respond to starch well, or grains. Some people can't handle dairy. Some do better with starch than fruit, etc.
  • M

    haidut

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    CO3C
    @mag-me yes. use google
  • P

    Where do people get their Vitamin B1 from without supplement?

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    ?
    Maybe look into gut bacteria and soil bacteria and how they are similar. I'm currently making a post about this but I'm still doing the reading. The bacteria in the gut can make B vits
  • HeightOptimizedH

    The formation of new growth plates is possible through hypoxia.

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    HeightOptimizedH
    @the-MOUSE definitely
  • HeightOptimizedH

    Simple ways to increase IGF-1.

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  • E

    Tips for naturally healing a dental pocket/cavity?

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    C
    raw carrots, maybe some antibiotics to cleanse it out then A D E K2 to max bone density+ lots of raw milk + aspirin + coffee with baking soda + Buteyko to boost hard tissue mineralization/calcification by upregulated minerals+oxidative metabolism induced higher CO2 production
  • F

    What B vitamin/s do you supplement? what dose, reason, and whats the effect.

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    R
    B1 at around 150mg a day cured me of all my digestive issues of "IBS", which I had struggled with for years, in a few days. Wasn't expecting it to do that at all, was taking it for something unrelated. I no longer need to take it daily and feel I need a "top up" of B1 every week or two. This was around 18 months ago and still have no issues.