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  • Scientific papers, books, blog posts. Discussion of whatever you find interesting and notable.

    627 Topics
    4k Posts
    U
    Increased Androgens: A pilot study on male volunteers (1 g/day for 1 month) found that DCI administration was associated with a +23.4% increase in testosterone and a +13.8% increase in dehydroepiandrosterone (DHEA). Reduced Estrogens: In the same study, DCI significantly reduced estrone levels (-85.0%) and reduced estradiol levels (-14.4%). Androgen Precursors: In addition to DHEA, other androgen precursors like epiandrosterone also increased (+39%). Aromatase Inhibition: DCI is believed to act as an aromatase down-modulator (inhibitor), reducing the conversion of androgens (like testosterone) into estrogens (like estradiol and estrone). D-chiro-inositol (DCI) acts to mimic insulin and also stimulate PDHP (pyruvate dehydrogenase phosphatase), which in turn dephosphorylates and activates PDH (pyruvate dehydrogenase). Acute Post-Meal Reduction: Clinical studies have shown that DCI, often in combination with myo-inositol, can acutely reduce the insulin spike that typically follows glucose or carb intake. Improved Sensitivity: By enhancing the activation of the insulin receptor pathway (specifically IRS2 and GLUT4), DCI allows the insulin already present in your system to work more effectively. Sparing Effect: Because DCI mimics certain insulin actions—like promoting glucose uptake into muscle and fat—it can have an insulin-sparing effect, meaning the body achieves the same blood sugar control with lower systemic insulin levels. taking D-chiro-inositol (DCI) or similar mimetics with carbohydrates can reduce the body's overall need for insulin by improving how cells process glucose.

  • Websites, newsletters, articles, podcasts, interviews, explainers, books, and other resources that relate to the work of Dr. Raymond Peat.

    62 Topics
    702 Posts
    C
    Cancer Treatments – from Research to Application MCS Foundations for Life, In memory of my dear wife Mihaela Catalina Stanciu https://www.cancertreatmentsresearch.com/ https://jeffreydachmd.com/cancer-articles/

  • Do you have a question? You can post it here, but you will only receive unqualified personal opinions and NOT medical advice in any shape or form. If something seems like medical advice but it's posted in this category, it's actually a personal opinion.

    1k Topics
    10k Posts
    alfredoolivasA
    @engineer Drop everything

  • From medical devices to supplements. Red lights, CO2 tanks, large trash bags, kuinone, and more.

    383 Topics
    4k Posts
    KorvenK
    @heyman said in Sperti vitamin D lamp is epic -- appetite is back after 6 years and my testosterone levels at an all-time high (700 ng/dl): customs gotta be a bitch Yes I had to pay +1000 usd to get this thing shipped to EU, but it was definitely a good investment since the bulbs last a long time

  • Recipes, food, meal prep, brands. Discuss them all here.

    233 Topics
    2k Posts
    sunsunsunS
    also posting here, someone on rpf posted about embryo rice, this is something I am looking into, apparently, and im not sure, it is usually brown rice , and in the package they will also put in the embryo from the processing of other rice into white rice to boost the nutrients. I might be wrong, it might also be brown rice that is only partially processed so that it removes something but retains the embryo, im not sure, it's sold at asian supermarkets and I haven't tried it yet.

  • Discussing pistol squats, concentric exercise, resting, and other forms of strength training.

    85 Topics
    1k Posts
    alfredoolivasA
    @sunsunsun https://www.youtube.com/watch?v=7f25pFhuAaY
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  • A

    High Cortisol correlates with high screen use

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    Crypt KeeperC
    Half the time I want to throw my computer off of the desk so, yes, I can see it raising cortisol for a variety of reasons. One time I did one of those 4-sample saliva cortisol tests that you take throughout the day, and there was an upwards blip in cortisol just before bed. I did a gaming session just before taking the sample.
  • A

    Vitamin D supplementation with fatty liver?

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    P
    It should help Vitamin D for treatment of non-alcoholic fatty liver disease detected by transient elastography: A randomized, double-blind, placebo-controlled trial PDF
  • the MOUSET

    ancedote ive noticed

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  • cs3000C

    14 medications later, T3 thyroid hormone gave a 33% remission rate for bipolar + a 84% improvement rate

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  • raytreatsR

    Best coconut water brand?

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    JenniferJ
    My favorites are Symbiosis and Genuine Coconut: https://cocosymbiosis.com/ https://genuinecoconut.com/coconut-water/ Next best are Harmless Harvest, 365 by Whole Foods Market fair trade and Trader Joe’s single origin, basically, coconut water sourced from Thai Nam Hom coconuts—I find it to be the sweetest and most fragrant variety I’ve tried: https://harmlessharvest.com/ https://www.wholefoodsmarket.com/product/365-by-whole-foods-market-organic-coconut-water-32-fl-oz-b08cw7vcgr https://www.traderjoes.com/home/products/pdp/single-origin-organic-coconut-water-065256
  • herayclitusH

    Protein and the Randle cycle

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    V
    @herayclitus check out Brad Marshall’s YouTube channel (fireinabottle). He shows how not even only tryptophan/methionine/cysteine slow metabolism as Ray said, but that BCAAs actually increase fat oxidation! Which can be a disaster in excess!!
  • E

    Toxic Bile Theory

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    B
    @Insomniac said in Toxic Bile Theory: Just thought I'd mention that In one of Grant Smith's streams he mentioned that even his ex-wife never bought into his ideas and she knows him much better than people paying him for advice. I noted. https://twitter.com/NutriDetect/status/1543574458044014593 Catch a glimpse of where someone's coming from and things may be clearer. https://twitter.com/NutriDetect/status/1778967836079296877 We're all aching in our own way.
  • F

    How to increase testosterone

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    BioEclecticB
    20 best testosterone-boosting diet plan foods. Hans Amato That's one resource.
  • D

    Light Exposure- A Lesser Mentioned Aspect of Bioenergetics

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    I
    I love getting lots of sun! Definitely a key to health.
  • R

    buteyko method

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    J
    I think this kind of breathing comes about naturally with increased CO2 and they are trying to mimic that way of breathing but I think it’s downstream of a good metabolism.
  • W

    Microcrystalline Cellulose in supplements

    adsorption
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    E
    I find that the fewer supplements I take, the better I feel.
  • T

    Soy-free Vitamin E derived from soy - do you think this matters ?

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    E
    @temple-of-salt I do not. I think there are compounds such as policosanols in wheat germ derived products such as Tocovit. Tocovit from Idea Labs is the best vitamin E product available today.
  • F

    thyroxine troubleshooting

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    F
    so essentially : porcine NDT with meals - raise only T3/FT3 to the optimal levels and my FT4/T4 drop to bottom and all severe symptoms appear. Raising only t3 levels helps only a bit with symptoms. taking T4 (on empty) and some NDT(with meals) - i see major improvements for some time before rt3 builds up and blocks metabolism and causes accumulation of the supplemental hormones to high levels in the serum.
  • P

    Why does cupping work?

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  • the MOUSET

    thoughts on taking mk677?

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    M
    @the-MOUSE Keto diet would probably make it worse. Growth Hormone increases free fatty acids, and adding that on top of ketosis will just augment it further. Taking it with B1, B3, and B7 might reduce it's negative effects. Just make sure you keep eating carbohydrate, because that b-vitamin stack could cause hypoglycemia.
  • D

    Fornication, Fraud, Foolishness, Faggotry, and Fapping are anti-metabolic.

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    C
    @Tahodama you still produce semen anyways even if you abstain and don't "reproduce" so the net energy investment into sexual function is more or less consistent most of the time independent of sexual activity levels hence why if you were to not ejaculate for a week you'd expel a higher volume of semen as your body keeps the process going independent of your engagement in it also why the nofap/semen retention claims that the commonly associated symptoms with post-ejaculation are due to sexual energy or semen loss is BS it's more to do with inflammation from prostaglandin release many have healed those downsides by Peating and/or anti-gut inflammation diets like carnivore
  • F

    Mikes healing corner.

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    E
    Lately I’ve been wondering if when stress hormones are high, and thyroid is supplemented, if it’s possible there’s a “grace period” where stress hormones are high, AND the supplemental thyroid combine for people experiencing wellness. Then, as the thyroid supplementation continues, the stress hormones drop and the net energy seems “lower” due to the lack of stress hormones with the supplemental thyroid. I think the solution is to continue thyroid supplementation and increase it as Peat recommends, (half a grain every two weeks). I can’t tell you how many time I’ve seen people take pro-metabolic substances, get a fantastic initial reaction, and then their previous symptoms return. At which point, they give up, or move on to another substance and repeat the process. This is exactly what happened to me too when I first began trying to incorporate Peat’s work. Not saying it’s what happening to you, but just something I’ve seen many times.
  • P

    This topic is deleted!

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  • cs3000C

    Sleep apnea cured in 2 months with either progesterone or thyroid (study)

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  • hwisdomH

    Burned egg shells bad?

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    M
    You burned the shit out of them if they're black, lol. But the cal carbonate is still probably okay. For future reference, I find saving the shells from boiled eggs to be the best. The boiling sterilizes them in the cooking process, so no need to reboil them. Just make like a big bowl of eggsalad or something to eat on for the week and you've instantly got a new batch of shells ready to be ground. You can let them air dry for a day before grinding them if you're worried about burning them in the oven.