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Subcategories

  • Scientific papers, books, blog posts. Discussion of whatever you find interesting and notable.

    627 Topics
    4k Posts
    U
    Increased Androgens: A pilot study on male volunteers (1 g/day for 1 month) found that DCI administration was associated with a +23.4% increase in testosterone and a +13.8% increase in dehydroepiandrosterone (DHEA). Reduced Estrogens: In the same study, DCI significantly reduced estrone levels (-85.0%) and reduced estradiol levels (-14.4%). Androgen Precursors: In addition to DHEA, other androgen precursors like epiandrosterone also increased (+39%). Aromatase Inhibition: DCI is believed to act as an aromatase down-modulator (inhibitor), reducing the conversion of androgens (like testosterone) into estrogens (like estradiol and estrone). D-chiro-inositol (DCI) acts to mimic insulin and also stimulate PDHP (pyruvate dehydrogenase phosphatase), which in turn dephosphorylates and activates PDH (pyruvate dehydrogenase). Acute Post-Meal Reduction: Clinical studies have shown that DCI, often in combination with myo-inositol, can acutely reduce the insulin spike that typically follows glucose or carb intake. Improved Sensitivity: By enhancing the activation of the insulin receptor pathway (specifically IRS2 and GLUT4), DCI allows the insulin already present in your system to work more effectively. Sparing Effect: Because DCI mimics certain insulin actions—like promoting glucose uptake into muscle and fat—it can have an insulin-sparing effect, meaning the body achieves the same blood sugar control with lower systemic insulin levels. taking D-chiro-inositol (DCI) or similar mimetics with carbohydrates can reduce the body's overall need for insulin by improving how cells process glucose.
  • Websites, newsletters, articles, podcasts, interviews, explainers, books, and other resources that relate to the work of Dr. Raymond Peat.

    62 Topics
    702 Posts
    C
    Cancer Treatments – from Research to Application MCS Foundations for Life, In memory of my dear wife Mihaela Catalina Stanciu https://www.cancertreatmentsresearch.com/ https://jeffreydachmd.com/cancer-articles/
  • Do you have a question? You can post it here, but you will only receive unqualified personal opinions and NOT medical advice in any shape or form. If something seems like medical advice but it's posted in this category, it's actually a personal opinion.

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    alfredoolivasA
    @engineer Drop everything
  • From medical devices to supplements. Red lights, CO2 tanks, large trash bags, kuinone, and more.

    383 Topics
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    engineerE
    @Mauritio was it the pheromones or the thermogenic part that made you consider 11 keto T?
  • Recipes, food, meal prep, brands. Discuss them all here.

    233 Topics
    2k Posts
    sunsunsunS
    also posting here, someone on rpf posted about embryo rice, this is something I am looking into, apparently, and im not sure, it is usually brown rice , and in the package they will also put in the embryo from the processing of other rice into white rice to boost the nutrients. I might be wrong, it might also be brown rice that is only partially processed so that it removes something but retains the embryo, im not sure, it's sold at asian supermarkets and I haven't tried it yet.
  • Discussing pistol squats, concentric exercise, resting, and other forms of strength training.

    85 Topics
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    alfredoolivasA
    @sunsunsun https://www.youtube.com/watch?v=7f25pFhuAaY
  • High fructose corn syrup ultra giga peaty?!?!?!

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  • Simplifying Bioenergetics for others

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    DonkeyDudeD
    @CO3 Where I live the topic is somewhat well known; for example, TV nutrition experts often promote a rule of thumb that the more liquid a dietary fat is in room temperature, the healthier it is. Confidently stating the opposite at least gets some attention, and if someone is unable to understand the solid fat/liquid oil distinction I'm not sure it's possible to simplify it even more.
  • T3 pooling from low cortisol?

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    R
    @BroJonas there has to be some truth because Ray suggested if you had cortisol issues to take t3 with pregnenolone. I'm not sure how prevelant it is or how much it related to low or high cortisol.
  • Aspirin recommendations?

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    DavidPSD
    Ray Peat email exchanges - Aspirin
  • Does mead acid form prostaglandins?

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    I
    @TexugoDoMel Great response, thank you!
  • Aspirin for uncoupling?

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    T
    @dan-dominic Thanks, dan-dominic, for posting that from him. I was mistaken in thinking he'd been banned years ago. I hope VoS considers putting in an appearance here at some point. If anyone has personal contact with VoS, please ask if he's still using his Co2 regulator/canula setup and/or if there are any other links where some of us who enjoyed following his experiments at RFP might read up on what he's been up to in terms of up-regulating metabolism since he left.
  • Accidentally cured my lactose intolerance using high-dose antibiotics

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    rayjeetR
    @skywxlker My digestion for milk has deteriorated a lot but is still a lot better to what it was before this round of antibiotics. Despite eating carrots and mushrooms regularly, I have not been able to keep my gut "cleansed". I felt clean and euphoric on eating/drinking food after the antibiotics. I dont know if I should do that again or what.
  • Frequency of the micro-nutrient dense foods (Liver, Oysters)

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    C
    @CO3 I just eat oysters when I crave them, which is usually about once a week and they always taste good, but if i just force myself to eat them when my body doesn’t want them they taste disgusting and i can barely swallow them without throwing up
  • why does the cheap store milk make me feel warm and depressed?

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    CreusetC
    @peatyourmeat Probably because coffee is anti-opioid: https://pubmed.ncbi.nlm.nih.gov/15088081/ Travis on the previous RPF used to talk about this kind of things.
  • accurate milligram scale suggestions?

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    yerragY
    @dangley Syringes and disposable polypropylene pipettes are very handy.
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    MauritioM
    @TheRealPeater @TheRealPeater said in I have been banned on the RPF for posting this study on Vitamin A...: @Mauritio This is a shame. I enjoyed my conversations with you and @Jam on the iodine threads. I think I'm OK posting in both places as I'm happy to give a generalised Low A approach a go...no different to how I gave SSKI a go... I'm not looking for a Great Wise Old Sage to shape my life, but I am happy to run with thoughts that interest me. I think thats totally fine. Many people have reported feeling better on a low A diet, although Im not sure how much of that is due to the absence of vitamin A and not the absence of all kinds of other things. I think its good that people get a feeling for how certains vitamins affect them. As Vitamin A can be anti-thyroid in higher doses, which is not a controversial opinion at all, just as this is not news, but has been said by Peat for decades.
  • What's the worst endocrine disruptor?

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    DavidPSD
    Atrazine is definitely a major endocrine disruptor. Chronic Exposure to the Herbicide, Atrazine, Causes Mitochondrial Dysfunction and Insulin Resistance https://journals.plos.org/plosone/article?id=10.1371/journal.pone.0005186
  • all woman = thyroid problems??

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    M
    @CO3 said in all woman = thyroid problems??: @basednigga2006 said in all woman = thyroid problems??: Idkk why but its disgusting, i will never marry a woman with thyroid problems Ooh you're one of those nvm Yeah kinda gave off incel vibes to me. Or at least someone too conceited to actually find a woman in the first place. The exceedingly far-right culture on this forum may become a problem in the near future. Just from a standpoint of growing this place. Most women wouldn't want to be here listening to dumb ass shit like that.
  • Cynomel / Cynoplus into Europe

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  • This topic is deleted!

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  • Help me pooped without irritating my skin

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    S
    @CO3 and watermelon?
  • best way to condition

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    voldtzeigV
    I'm using bloo twice a week and afterwards I take some coconut oil and condition my hair with it. So far it has worked wonders, argan oil is also good. Just make sure to not use too much so you ruin your scalp with the fat.
  • GHK-Cu

    Moved
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    onliestO
    @b_well_insomnia just made a serum with glycerin and saline. will update in a week or so
  • This topic is deleted!

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  • Marek Diagnostics - Affordable Lab Testing

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