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Subcategories

  • Scientific papers, books, blog posts. Discussion of whatever you find interesting and notable.

    627 Topics
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    U
    Increased Androgens: A pilot study on male volunteers (1 g/day for 1 month) found that DCI administration was associated with a +23.4% increase in testosterone and a +13.8% increase in dehydroepiandrosterone (DHEA). Reduced Estrogens: In the same study, DCI significantly reduced estrone levels (-85.0%) and reduced estradiol levels (-14.4%). Androgen Precursors: In addition to DHEA, other androgen precursors like epiandrosterone also increased (+39%). Aromatase Inhibition: DCI is believed to act as an aromatase down-modulator (inhibitor), reducing the conversion of androgens (like testosterone) into estrogens (like estradiol and estrone). D-chiro-inositol (DCI) acts to mimic insulin and also stimulate PDHP (pyruvate dehydrogenase phosphatase), which in turn dephosphorylates and activates PDH (pyruvate dehydrogenase). Acute Post-Meal Reduction: Clinical studies have shown that DCI, often in combination with myo-inositol, can acutely reduce the insulin spike that typically follows glucose or carb intake. Improved Sensitivity: By enhancing the activation of the insulin receptor pathway (specifically IRS2 and GLUT4), DCI allows the insulin already present in your system to work more effectively. Sparing Effect: Because DCI mimics certain insulin actions—like promoting glucose uptake into muscle and fat—it can have an insulin-sparing effect, meaning the body achieves the same blood sugar control with lower systemic insulin levels. taking D-chiro-inositol (DCI) or similar mimetics with carbohydrates can reduce the body's overall need for insulin by improving how cells process glucose.
  • Websites, newsletters, articles, podcasts, interviews, explainers, books, and other resources that relate to the work of Dr. Raymond Peat.

    62 Topics
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    C
    Cancer Treatments – from Research to Application MCS Foundations for Life, In memory of my dear wife Mihaela Catalina Stanciu https://www.cancertreatmentsresearch.com/ https://jeffreydachmd.com/cancer-articles/
  • Do you have a question? You can post it here, but you will only receive unqualified personal opinions and NOT medical advice in any shape or form. If something seems like medical advice but it's posted in this category, it's actually a personal opinion.

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    alfredoolivasA
    @engineer Drop everything
  • From medical devices to supplements. Red lights, CO2 tanks, large trash bags, kuinone, and more.

    383 Topics
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    engineerE
    @Mauritio was it the pheromones or the thermogenic part that made you consider 11 keto T?
  • Recipes, food, meal prep, brands. Discuss them all here.

    233 Topics
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    sunsunsunS
    also posting here, someone on rpf posted about embryo rice, this is something I am looking into, apparently, and im not sure, it is usually brown rice , and in the package they will also put in the embryo from the processing of other rice into white rice to boost the nutrients. I might be wrong, it might also be brown rice that is only partially processed so that it removes something but retains the embryo, im not sure, it's sold at asian supermarkets and I haven't tried it yet.
  • Discussing pistol squats, concentric exercise, resting, and other forms of strength training.

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    alfredoolivasA
    @sunsunsun https://www.youtube.com/watch?v=7f25pFhuAaY
  • Killing serotonin without drugs

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    SantoshS
    @PeaterDinklage said in Killing serotonin without drugs: @Santosh Does this account for the diet he described or are amendments necessary for such a cure? It works on any diet
  • My colitis is returning since taking progesterone

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  • Temp after breakfast lower than upon waking

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    KvirionK
    BTW There is a nice video explaining thyroid health in detail https://twitter.com/natelawrence_/status/1766186130985107582 There is also a good article that quotes Ray's advice about thyroid https://www.functionalps.com/blog/2012/03/25/ray-peat-phd-on-thyroid-temperature-pulse-and-tsh/ Sometimes all that advice needs to be taken to progress with thyroid health.
  • Accutane

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  • Receeding gum

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    WildflowerW
    @Samyo Dr. Ellie Phillip's protocol works best for me. I know many people do not agree with what she recommends, but her protocol stopped my gums from bleeding and with the progression of gum recession. I don't use the ACT mouthwash. I swapped it out with a salt & xylitol rinse from CVS. But I do use the other mouthwashes and toothpaste that she recommends. One of her best and most informative interviews was with Patrick Timpone circa 2017. If you can find that, listen to it. She explains everything so well.
  • Took 3mcg of T3. Felt almost nothing.

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    @Shar_to_the_dae https://open.substack.com/pub/natelawrence/p/thyroid-hormone-metabolism-and-supplementation?r=18iouf&utm_medium=ios This article is fantastic, I highly recommend having a read
  • Mercola radically revises health advice based on Ray Peat's research

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    @C-Mex said in Mercola radically revises health advice based on Ray Peat's research: [image: 1709233777543-share-selection-square.jpg] He makes reference both Ray Peat and Georgi in the following article: https://takecontrol.substack.com/p/basic-tips-for-optimal-health He had to "radically revise" what any freshman biochem student could tell you about beta oxidation...simply marvelous people took health advice from that idiot. These are the types of dense people in the keto crowd folks.
  • Resources

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  • The Blood Work thread

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  • This topic is deleted!

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  • do you take electrolytes alongside sugar/dextrose drinks?

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    the MOUSET
    @the-MOUSE also can mixing sugar and milk affect glycemic index? maybe makes it harder to digest the sucrose?
  • Need advise on supplements for daily alcohol user

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    CO3C
    @happyhanneke Yes!
  • safe long term 5ht3 antagonist use?

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    @the-MOUSE Potassium bicarbonate would probably work really well. I've never used it before but the K in it would be absorbed really well. I get most of my potassium from fruits, meat, and coconut water. Just one 12oz tetra pack of coconut water has like 1 gram of potassium in it, so it's loaded with potassium. Potassium will help with fluid retention as well. I make my magnesium bicarbonate with mag hydroxide and carbonated water. I would venture to guess you do something similar to make potassium bicarbonate.
  • Thyroid Therapy Success Stories

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  • thoughts on cypro alternatives?

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    @the-MOUSE the alternative I’m familiar with is ketotifen, and of course, diphenhydramine. They both work well but not as well as cyproheptadine. Ketotifen is closest probably.
  • Best type of Thiamine

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    AppaA
    I tried TTFD, Sulbutiamine, Benfotiamine and Thiamine HCL They all share the improvment in physical energy and improved breathing in my opinion. Benfotiamine was more effective for peripheral neuropathy. TTFD feels very psychedelic and is in my opinion the best form for intellectual tasks but it comes with a lot of side effects compared to the other forms. Sulbutiamine feels very physical, it's my favorite form because of the physical kick in the ass effect it provides. Overall they are all good at increasing levels of thiamine. TTFD is better when the goal is to increase central nervous system levels of thiamine. Benfotiamine for neuronal pain, it was the only form that was aleviating my headaches and tingling in extremities. Sulbutiamine is great for physically demanding tasks. Thiamine HCL is doing a little bit of each one and requires higher doses compared to the other forms.
  • Schizo alt health figures

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    ?
    @C-Mex I think I'm just looking at it from a different angle. Bear in mind that there has been a massive gov't sponsored censorship and slander campaign against vaccine skeptics, doctors and scientists speaking out against the vaccine, and people researching or questioning gain-of-function or bioweapons research. This censorship/disinformation campaign is all coming to light and there is litigation in the courts and even the Supreme Court as we speak as a First Ammendment issue. Now that the "conspiracy theories" are all proving to be true, I'm seeing these same individuals being targeted in some new counter narrative that they are not to be trusted because they've believed all along that viruses exist and must be part of some hidden gov't agenda, etc. That's my observation.
  • Is this website haidut's?

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    SugarS
    @CO3 Seems like it's purposely ripping off the idealabs product name so when people search for pansterone Google directs them to their site instead of the idealabs website which I'm not sure is properly optimized for search engines. You have to keep in mind how cheap DHEA and pregnenolone are on a bulk scale, and how easy it is to mix the products together and slap a label on a bottle, if this copy website even has a product to ship.
  • VITAMINE D RECEPTORS AND androgenetic alopecia

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  • Is dried/dehydrated fruit peaty?

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    C
    Fresh ripe fruit is always better, but there’s nothing wrong with having some dried fruit. I like dried mango, very yummy.