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  • Scientific papers, books, blog posts. Discussion of whatever you find interesting and notable.

    641 Topics
    4k Posts
    AlphaZanceA
    Abstract Alcoholic beverages produced by fermentation (e.g., beer and wine) are powerful stimulants of gastric acid output and gastrin release in humans. The aim of this study was to separate and specify the gastric acid stimulatory ingredients in alcoholic beverages produced by fermentation. Yeast-fermented glucose was used as a simple model of fermented alcoholic beverages; it was stepwise separated by different methods of liquid chromatography, and each separated solution was tested in human volunteers for its stimulatory action on gastric acid output and gastrin release. Five substances were detected by high-performance liquid chromatography and were analyzed by mass spectrometry and 1H-13C nuclear magnetic resonance spectroscopy. At the end of the separation process of the five identified substances, only the two dicarboxylic acids, maleic acid and succinic acid, had a significant (P < 0.05) stimulatory action on gastric acid output (76% and 70% of fermented glucose, respectively), but not on gastrin release. When given together, they increased gastric acid output by 100% of fermented glucose and by 95% of maximal acid output. We therefore conclude that maleic acid and succinic acid are the powerful stimulants of gastric acid output in fermented glucose and alcoholic beverages produced by fermentation, and that gastrin is not their mediator of action. ... When tested separately, oxalic acid, acetic acid, and L(+)-lactic acid had no stimulatory effect on gastric acid output. Maleic acid and succinic acid, however, significantly increased gastric acid output by 76% and 70%, respectively, of fermented glucose (Figs. 2 and 4). When given together in the concentrations present in beer, maleic acid and succinic acid significantly increased gastric acid output by 95% of MAO(maximal acid output) and 100% of fermented glucose. J. Clin. Invest. 103:707–713 (1999) https://pmc.ncbi.nlm.nih.gov/articles/PMC408116/

  • Websites, newsletters, articles, podcasts, interviews, explainers, books, and other resources that relate to the work of Dr. Raymond Peat.

    62 Topics
    702 Posts
    C
    Cancer Treatments – from Research to Application MCS Foundations for Life, In memory of my dear wife Mihaela Catalina Stanciu https://www.cancertreatmentsresearch.com/ https://jeffreydachmd.com/cancer-articles/

  • Do you have a question? You can post it here, but you will only receive unqualified personal opinions and NOT medical advice in any shape or form. If something seems like medical advice but it's posted in this category, it's actually a personal opinion.

    1k Topics
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    gg12G
    Typically your liver is already taking hits, Calcium in the milk seems very beneficial, But the milk slows my motility and makes my stomach bloated , irritated, My skin might break out and I get sleepy. Ive been drinking it every day for about a week and a half, Things are sort of better? Do I just keep drinking it?

  • From medical devices to supplements. Red lights, CO2 tanks, large trash bags, kuinone, and more.

    386 Topics
    4k Posts
    alfredoolivasA
    @BioEclectic said in Best thyroid type in context of combining with hormones?: If i may ask, and if it were you, which thyroid type would you choose? Reasons why aren't necessary, i can even make a choice based on consensus, and the responsibility would be totally my own. It is a tough choice imo. T3. It made me incredibly catabolic. And it's effects on fat loss were dissapointing. I really didn't benefit from it at all. Now, I use 50-75mcg t4. Feeling and looking much better. Considering your gender and your steroid protocol, you probably will convert t4 fine if you want to consider that.

  • Recipes, food, meal prep, brands. Discuss them all here.

    236 Topics
    2k Posts
    LucHL
    A single portion (240ml) of UHT milk is like welcoming just one tourist in Venice. Not overcrowded. You get the value of the nutrient, but the load is manageable, allowing your small metabolism to process and keep the not-well-fit amino-acid under control (not used). If someone overloads himself with one gallon at a time, twice a day, it won't make you "more nourished." It will make you tired and leave your body feeling crowded and overworked by the demands of processing it all, when something is not well manufactured / recognized. Management is all. Even if you don’t perceive it. And don’t tell you know someone who … Finally: Think, perceive and act, as someone not far from here would say “If UHT milk is the only option, a single portion (~240 ml or half a gallon) is manageable. Think of it like one extra car on a quiet road — the system absorbs it without stress. Moderation keeps the metabolism in control. A moderate amount keeps the metabolism in control of what it can process and discard.

  • Discussing pistol squats, concentric exercise, resting, and other forms of strength training.

    86 Topics
    1k Posts
    R
    @LunaticRed what @alfredoolivas said along with inhibiting cortisol, positive androgenic effects like increased strength, bone growth, anti-anxiolytic, controls blood sugar, controls inflammation from endotoxin. The list goes on. In reality, it is the TRUE male hormone.
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  • CO3C

    Is this website haidut's?

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    SugarS
    @CO3 Seems like it's purposely ripping off the idealabs product name so when people search for pansterone Google directs them to their site instead of the idealabs website which I'm not sure is properly optimized for search engines. You have to keep in mind how cheap DHEA and pregnenolone are on a bulk scale, and how easy it is to mix the products together and slap a label on a bottle, if this copy website even has a product to ship.
  • B

    VITAMINE D RECEPTORS AND androgenetic alopecia

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  • R

    Is dried/dehydrated fruit peaty?

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    C
    Fresh ripe fruit is always better, but there’s nothing wrong with having some dried fruit. I like dried mango, very yummy.
  • H

    Advice on dosage Pansterone and Oxidal

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    H
    @annis thank you!
  • ?

    This topic is deleted!

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  • zoroZ

    Malassezia nuking protocol

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    CurmudgeonAppleC
    @mexican_coke_fan said in Malassezia nuking protocol: @CurmudgeonApple Can you share more about how you'd take each of those things? Just eat them throughout the day? The meat, or the other things i mentioned? I take the marshmallow root here and there throughout the day, aloe on an empty stomach first thing in the morning, carrot salad the same, castor and black seed oil a tsp here and there throughout the day, but usually before meals. Broths, meat etc with meals, or just as snacks, and the psyllium i usually take before meals. It's been better than Cascara for me in terms of bowel health(stung like hell. Watery cow patties) despite everything Peat claimed about soluble fiber, it's not been my experience. though, I always suspected Peat might have had gut permeability from his recreational use of antibiotics. Even a tiny dosage of a tetracyline can annihilate an entire population of niacin forming bacteria and oxalobacter. There is no such thing as a "safe" amount of antibiotic use IMO and i would be generally leery of anything Peat had to say about the gut. IME at least. YMMV
  • E

    Dave Asprey is a full on Peatard????

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  • the MOUSET

    why do i have low appetite and nausea in morning?

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    E
    when you wake up your blood sugar has fallen several times during the night and you have suffered high adrenaline and cortisol to bring it up, and this is a stress reaction. The result can be feeling crummy and nausea in the morning. You need to eat foods that support good blood sugar during sleep.
  • P

    Lead-Tainted Applesauce Sailed Through Gaps in Food-Safety System

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    R
    @potato this is so sad. I’ve been making and freezing all my baby food since I do not trust these companies.
  • albionA

    Trepanning

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  • banquos-ghostB

    This topic is deleted!

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  • voldtzeigV

    Body temperature

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    O
    @voldtzeig Ok cool. For eardrum, I think the target should be even higher than 98.6. E.g. Peat said: "Old people in particular can have brain at a “good temperature, oral 98.6 (37C), eardrum 99.5, for example” … but they’re producing less energy and that shows up as an extreme gradient from the extremities to the brain" from https://bioenergetic.life/clips/74ded?t=5569&c=107. So lots of room to improve!
  • AJdaJuicemanA

    This topic is deleted!

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  • the MOUSET

    do you have lunula on nails?

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    R
    @CO3 LOL
  • GreekDemiGodG

    High carb, high plant diversity diet?

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    GreekDemiGodG
    I have talked with someone who had success in rebuilding her microbiome. She saw improvements within 3 months, but she said that generally repopulating the microbiome is a long term process and can take years. Makes you wonder why people quit too soon, they expect results too early. I too didn't have the patience. Her approach was probiotics, and slow reintroduction of plants, fibers, veggies. She saw big improvements in depression, candida, bloating after a couple months.
  • S

    Under eye support/tear troughs/hallow indents

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    izkrovI
    I don't have much experience, but I think I understand what you're saying. I found some studies suggesting that a Frankel Appliance could help with what you're describing. In this study they conclude that the "Significant alveolar and apical base expansion was found in the treatment group". It seems like the alveolar and apical base is just the bone on the base of the upper teeth, so if they shift everything forward and help your tongue guide the other tissue forward, it'll probably make the features less hollow. Though, some example/reference photos would be helpful just to be sure.
  • R

    meds.com.mx orders / payment

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    R
    I bought from there recently, and it took a few days for them to confirm the payment after I emailed the template. Arrived quickly though, all good.
  • BrandonB

    Progest-E/Progesterone Questions

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    CO3C
    @Brandon Hmm. You can try! A tiny bit of olive oil to dissolve is best. Maybe try slathering a bit on a little zit or something. It's just the way I tried it! If you're gonna try orally I would suggest doing 2 corn kernel sized drops at once, rubbed into the gums. My idea is just that it would have a significant, palpable effect, which can help to make it a valuable tool once you understand it.
  • A

    Dopamine fasting/technology break will help my mental health?

    mental technology
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    ?
    @AndrewPeatMatrix Turn off all notifications (e.g. vibrations, sounds) on your phone. Stop scrolling on social media and begin reading books instead. Don't watch internet videos. Screen usage/culture is highly anti-social and neurologically dysfunctional, and that's saying nothing about EMF or blue light. It also lends itself to hyperstimulating addictions like pornography, which will cause further brain decay on its own. Dopamine is very important to keep elevated, but you should do it by resensitizing yourself to the elements (i.e. earth, water, air, fire), animals, people and so on - not by "digital culture" (Ray Peat's term) with its degenerative cyber simulacra of reality.
  • SugarS

    What do you believe causes schizophrenia/psychosis?

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    C
    Probably worth noting as well that marijuana has very high levels of heavy metals, absorbs a lot of lead and cadmium from the soil it’s grown in, a high concentration of lead in the bloodstream is found significantly associated with an elevated risk of schizophrenia.