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  • Scientific papers, books, blog posts. Discussion of whatever you find interesting and notable.

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    yerragY
    @Ena said: Yes, statins possess antibacterial properties, so in principle they will introduce LPS by helping the white blood cells to kill bacteria. But it's a strange wording, so I don't understand what he means either. @Ena said: Yes, statins possess antibacterial properties, so in principle they will introduce LPS by helping the white blood cells to kill bacteria. But it's a strange wording, so I don't understand what he means either. I think so too. Stating are antibacterial though they are not marketed to be anything else but a cholesterol lowering drug. Otherwise why would they lead to increasing endotoxins.
  • Websites, newsletters, articles, podcasts, interviews, explainers, books, and other resources that relate to the work of Dr. Raymond Peat.

    62 Topics
    703 Posts
    CiceroC
    I noticed the reprint of Nutrition for Women says "100 short articles by Ray Peat, PHD," where the old one said "92...". What did they add to it? Also, note that From PMS to Menopause is for sale on Peat's website but not Amazon, and Peat's website doesn't have Generative Energy. Weird. I wonder if Katherine gets more of the money if you order from Peat's site. I'd imagine so.
  • Do you have a question? You can post it here, but you will only receive unqualified personal opinions and NOT medical advice in any shape or form. If something seems like medical advice but it's posted in this category, it's actually a personal opinion.

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    @ChroncStresChris yes generally speaking, because DHT dries you out and may actually reduce tesosterone testosterone is "wet" and is needed with dht, dht is "dry"
  • From medical devices to supplements. Red lights, CO2 tanks, large trash bags, kuinone, and more.

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    D
    Who knows if this Lead Safe Mama person is actually reliable or not? I continue to use Great Lakes because I don’t know any better brand.
  • Recipes, food, meal prep, brands. Discuss them all here.

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    JenniferJ
    @Mossy, do you mean the brand or type of French bread like the baguette? I was trying to think of popular French brands, but couldn’t come up with any. That’s great! My grandmother used red potatoes too for her potato salad. Aside from digestibility—baby potatoes typically being easier to digest—the best potato really depends on its growing conditions and less so the variety, IME. After spending months testing numerous varieties from different suppliers, I (happily) settled on the baby Yukons. They’re from a local supermarket chain and even better than the Upstate Abundance—they’re consistently so creamy and flavorful that they don’t need any added butter or salt, but they’re half the price and available year round. Alexandre is excellent, yes, but prior to caring for my dad, the majority of my dairy (and eggs) came from a local 100% grass-based, biodynamic, A2 certified (raw) dairy farm that practices Calf at Foot where the calf stays with its mother, something that’s important to me. I’ve known the owner for over 16 years now. I found his farm just after my spine collapsed and I was recovering from veganism. After hearing what happened to me, he started supplementing his herd’s diet with sea minerals to give me the most nutrient dense milk possible. The man is an earth angel. We geek out on health and science whenever I get the chance to visit the farm. He introduced me to the French scientist Louis Kervran and his controversial theory of biological transmutation and last time I saw him, he had started using a refractometer to test the Brix of his herd’s milk. Thank you for the heads-up on Vital Farms. I saw a YouTube video on it a month or so ago. I had always assumed their hens were fed supplemental feed containing soy as it’s a common practice in the industry, even for pastured. I don’t know of any brand on the market whose hens are fed entirely on pasture—Angel Acres Farm, owned by the ‘Strong Sistas’, sells eggs that are tested to be low in PUFA, though—or if it’s even possible to maintain the health of the hens and egg production to meet demands, while keeping the cost of eggs reasonable enough to not offend the consumer. With that said, I haven’t bought their eggs since maybe 2024. I buy a “humanely hatched” brand that uses the technology in-ovo sexing to end the practice of chick culling. It’s great that you’re tolerating bananas better. That’s another good indication your health has improved. Did cooked bananas also cause a serotonin response, previously? If I’m not mistaken, Ray recommended cooking them because of the raw starch. I used to only tolerate them raw when overripe. I haven’t had them in quite some time, though. My diet was further simplified because I’m having to prepare 6 meals a day, currently. Thankfully, I overcame the dysautonomia so the only effect protein has on me now is positive, but the majority of my fuel came from potatoes—I was averaging upwards of 4 lb daily. The concentrated carbs helped, but it was immersing myself in nature regularly on the trail that was most responsible for calming my nervous system and restoring my thyroid function so my adrenals weren’t having to compensate with adrenaline. I had this epiphany that it was not my body that needed convincing it was safe to relax, but me who needed it. I’ve heard it said that we should get out of our comfort zone, but it occurred to me that I’ve never had one. Figuratively speaking, I’ve been putting out fires since I was a child and always preparing for the next one. I knew I needed to take my healing beyond the cell back to the self, but it was challenging to do so when I felt so disconnected from myself, hollow even, since my mum’s passing and distracting myself with the demands of caring for my dad wasn’t going to reconnect me. I didn’t overcome the dysautonomia overnight, but I stayed committed to getting out on the trail at least 4 days a week, and one day, while on the last mile stretch of one of my hikes, I had a moment, a breakthrough, when there was what I can only describe as a lifting of the veil between this world and heaven. I thought I knew peace, but just like hell has no floor, the depths of it are endless, I discovered that day that heaven has no ceiling. To go from feeling completely disconnected to feeling connected to not just myself but everything, to know life’s tragic realities, intimately, and at the same time its miraculousness, was life-affirming. I was reminded that the source that created the mountains I’ve climbed is the same source that created me to be just as enduring, and whatever comes my way I can handle it because in hindsight I always have, and where, in the past, I would have gone into fire-extinguisher mode hearing the doctor say my dad had what killed my mum, I felt at ease, in the flow and have remained so. I’m not just drifting around the ocean on a surfboard, at the mercy of the water. I am the water. And thank you. ️ Yes, you can definitely relate. Being a caregiver is a lot, but I’m just so grateful to have more time with my dad that I didn’t have with my mum.
  • Discussing pistol squats, concentric exercise, resting, and other forms of strength training.

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    C
    I thought aspirin and/or baking soda w water is good for afterwards? Gummy bears or fruit before and during lifting, no?
  • How to get rid of dark circles?

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    cs3000C
    @Cezar4911 its often showing hypoxia or leaky vessels (low oxygen tissue, skin around the eyes is thin so shows it clearly). u can see this at peoples finger tips / toes / tip of nose / lips in people with poor circulation, Cyanosis https://upload.wikimedia.org/wikipedia/commons/thumb/d/dc/Cynosis.JPG/1024px-Cynosis.JPG , milder version of this common sign of hypothyroidism (can be iron deficiency, sleep apnea, poor lung heart function etc stuff that effects bloodflow rbc bodyheat). ray said he noticed this going away when people fixed hypothyroidism
  • This topic is deleted!

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  • Healing ups and downs - PEM query

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    J
    @LucH thank you for that. I have also been taking low dose b- complex, but it prob doesn't have enough b2. I find supplementing the b vitamins to be so complex, with so many pitfalls. You need x to make y work, but if you take too much x, it will deplete z etc etc. It's an endless minefield. I'm going to just work on thyroid and diet, and try and get enough b vitamins from milk and liver. Even if I don't fix all my issues, I should still make real progress.
  • Beef gelatin

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    yerragY
    @Cezar4911 I can buy beef tendons that have been well processed such that it is all white and transparent. It steams well into a clear gelatin that can also be used as jello. Costs me $7/kg wet and assuming 75% moisture, translates to $28/kg dry. I consume this in 2 months. Beef tendons are best IMHO because it is free from any endotoxins. Buying gelatin is fraught with uncertainty as to sourcing, as you have to trust the word of the processor/manufacturer. And you can trust no one you don't know.
  • How much butter do you put in potatoes?

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    JenniferJ
    @Cezar4911, I usually put roughly 2 tablespoons of butter per kilo of potatoes.
  • Trynna cop som halal Armour (NDT)

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    Milk DestroyerM
    In Sweden, I don't think you'll find a bovine variation of an Armour alternative at all, unfortunately. Bovine thyroid glandular supplement is probably obtainable there but the quality is dubious and you have no idea what ratio of t4:t3 you'd be getting. Might be worth pinning more of your thoughts on diet and lifestyle/environment rather than spending a lot of money on rare imported thyroid drugs.
  • Secondary Hypogonadism

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    KvirionK
    @mavuue If your cortisol is elevated (probably is) it would be helpful to lower it too (together with estrogen). https://testonation.com/2019/06/09/43-ways-to-lower-cortisol-that-work/ In general, the best approach is to focus on improving your overall health, especially metabolism with thyroid optimization (as others already mentioned). https://www.youtube.com/watch?v=-FTOVRcUqTs Stay away from reductionistic desperate steps like partially estrogenic Clomid or inconvenient HCG...
  • thoguhts this vid

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    the MOUSET
    @BroJonas jfl
  • Oyster alternative? Fish and Shellfish Allergy

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  • I have hit rock bottom please help.

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    Hando-JinH
    Thyroid.
  • Low salt diet and water restriction

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    NNightN
    @Razvan Manganese is interesting as it's part of the SOD2 enzyme which is particularly needed in case of "dehydration". Empirically, I've also found it to gave me what (the energy) you described. But I don't believe it stayed that way very long, I don't remember well. Also, manganese is interesting as it seems to do positive things regarding the AQP4 aquaporin, which is involved in the glymphatic system (cleansing system of the brain). In brain, astrocytes predominantly take up and accumulate manganese and are thus vulnerable to its toxicity. Manganese was shown to induce cell swelling in cultured astrocytes, and oxidative/nitrosative stress (ONS) mediates such swelling. As aquaporin-4 (AQP4) is important in the mechanism of astrocyte swelling, we examined the effect of manganese on AQP4 protein levels in cultured astrocytes. Treatment of cultures with manganese increased AQP4 protein in the plasma membrane (PM), whereas total cellular AQP4 protein and mRNA levels were unchanged, suggesting that increased AQP4 levels is due to its increased stability and/or increased trafficking to the PM and not to its neosynthesis. Aquaporin-4 in manganese-treated cultured astrocytes They talk about AQP4 in negative terms here but it really seems to be fundamental for the glymphatic system, for example: CSF transport is facilitated by the expression of aquaporin-4 (AQP4) water channels on the perivascular endfeet of astrocytes. Mice with genetic deletion of AQP4 (AQP4 KO) exhibit abnormalities in the brain structure and molecular water transport. Loss of aquaporin-4 results in glymphatic system dysfunction via brain-wide interstitial fluid stagnation
  • PUFA & weight loss

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    @LucH thank you for the "in depth" reply.
  • Danny Roddy on "avoid liquid thyroid"

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    secondkelpingS
    @Harlock hmmm, I feel like there is a large difference between people who are on the skinny hypothyroid side versus the fat hypothyroid side. I'm on the fat side and had to up my dose of thyroid by several times to feel anything. I have used tyronene, tyromix, and tyromax. Tyromax was really the only one that needs to be shaken thoroughly to be sure of the dose, but even then, I've taken high thyroid doses through Forefront NDT both the 130mg and the 65mg (65mg is what I take now). I feel like thyroid can certainly be dangerous, but we're talking about 2 different types of hypothyroidism sometimes. Maybe people who need super specific doses of thyroid are different than those like me who can down 130 mg of T3/T4 mix about 1:4-ish. Then lower to 65 mg with the same ratio with minimal change in effect... Idk, I understand Danny wants to stay true to RP, but I'm into Bulgarian dark peating lol.
  • countertop reverse osmosis filter

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    jhpJ
    @RealNeat Do you know where I would be able to get a aquanui or similar filter in the UK?
  • Increasing DHT

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    @Crypt-Keeper What I meant by 100ml was to ease the equation, so if you want a 5% solution with 5g dht, you would need 100ml dmso, but if you want a 5% solution with 2.5g dht, you need 50ml dmso. About the moisturizer, good point, but dmso itself is very liquidy so some gel like substance like pure aloe vera could make application easier. Totally not needed though. So if you dissolved 5grams of dht into 100ml dmso, the concentration would be 5%, and if you applied 1ml of that solution, you would get 50mg dht. PS: The prior post talks about milligrams instead of grams so mb.
  • What do you all think about Goatis aka Sv3rige?

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    thyroidchor27T
    @EustaceBagge said in What do you all think about Goatis aka Sv3rige?: I agree with you, he looks very calm and has nice skin that is not just superficially good looking but has a great quality to it. [image: YxeQeT.gif]
  • "Glucose Loading" protocol, a la Dr Stephens - A Critique

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    @LetTheRedeemed said in "Glucose Loading" protocol, a la Dr Stephens - A Critique: @Janelle525 yes. I’m definitely at the pinnacle of my salt intake, haha. I lowered my sugar consumption, or at least balanced it with spreading out my protein intake, and the headaches went away. That was a while ago. And I definitely still consume quite a bit of sugar: several sodas/juice/sweat teas per day, plus spoonfuls of honey with milk, and ice cream. I’ve definitely found my max sugar capacity Haha okay!
  • Transdermal Application Poll

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    Crypt KeeperC
    I'm going to not vote because I haven't felt an effect from anything I've put anywhere transdermally yet. Although I've only tried arms, tops of feet, stomach and navel.
  • threonine/serine - can this substitute glycine?

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  • got palpiatations eating butter

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    F
    Are you sure it is the heart? I think it could be the gallbladder secreting more bile acid to digest the butter, sometimes it happens to me after a fat heavy meal.