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  • Scientific papers, books, blog posts. Discussion of whatever you find interesting and notable.

    689 Topics
    5k Posts
    sunsunsunS
    @CrumblingCookie nice…

  • Websites, newsletters, articles, podcasts, interviews, explainers, books, and other resources that relate to the work of Dr. Raymond Peat.

    62 Topics
    703 Posts
    CiceroC
    I noticed the reprint of Nutrition for Women says "100 short articles by Ray Peat, PHD," where the old one said "92...". What did they add to it? Also, note that From PMS to Menopause is for sale on Peat's website but not Amazon, and Peat's website doesn't have Generative Energy. Weird. I wonder if Katherine gets more of the money if you order from Peat's site. I'd imagine so.

  • Do you have a question? You can post it here, but you will only receive unqualified personal opinions and NOT medical advice in any shape or form. If something seems like medical advice but it's posted in this category, it's actually a personal opinion.

    1k Topics
    11k Posts
    alfredoolivasA
    @engineer Fair, lol about the creatine

  • From medical devices to supplements. Red lights, CO2 tanks, large trash bags, kuinone, and more.

    395 Topics
    4k Posts
    J
    @Mauritio I got mine from a german supplier https://shop.es-drei.de/salze/salicylate/1227/natriumsalicylat-min.-99-5-zur-analyse?c=323

  • Recipes, food, meal prep, brands. Discuss them all here.

    238 Topics
    2k Posts
    JenniferJ
    @Mossy, yes, tale as old as time. It’s scary to think how dangerous some hand-me-downs can be, that they aren’t created in a vacuum, but a byproduct of something far more reaching, since we are connected to everything that is and ever was, man being a strand in the web of life and all. Actually, it was my dad’s lack of fitness that bothered him more than anything, but I had a heart-to-heart with him, reminded him of everything we’ve been through with my mum’s passing and his cancer diagnosis, spoke from experience of having to fight to walk again after my spine collapsed, and when he got down on himself, said he was never going to get better, I reminded him that doctors said I would never get better and I’m climbing mountains again, something I didn’t do by giving up. I think it’s important that we keep each other honest so I was a pain in his arse when he made excuses (lol), and he’s finally taking his recovery seriously. He started napping twice a day, eating and taking his supplements on schedule, and he’s now up to 2 mile hikes with ease. I just switched his thyroid from TyroMix to TyroMax and within two doses, he told me he got his appetite back so another victory. I’m sorry you’ve experienced it, too, Mossy. It’s a lot. In my case, the lack of help from abled family isn’t stubbornness. Some take things for granted, don’t realize what they have until it’s gone, but I guess that’s their cross to bear, not mine. When my dad passes, I’ll have no regrets, just like when my mum passed, because I knew what I had when I had it, and did everything in my power to nurture and protect it. I mean, what is a family, if not for that? Blood may be thinker than water, but love is thicker than blood, and as far as I’m concerned, love is a verb. It means little, without action. Oh, okay. You meant actual milk bread. If I’m not mistaken, it’s popular in Japan. I have a few milk bread recipes by Japanese bakers saved on YouTube. It does look light and fluffy. That’s why I tend to stick with brioche, but you’ve inspired me to make milk bread. YAY! I’m so glad your dad liked the lasagna.

  • Discussing pistol squats, concentric exercise, resting, and other forms of strength training.

    94 Topics
    1k Posts
    sunsunsunS
    @PrinceTrebata alfred haș the power of will so basically anything would do the trick for him
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  • jamezb46J

    Negative Feedback Mechanism of steroids on Gonadotropin Releasing Hormone

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  • CO3C

    Just got an email

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    MauritioM
    "It seems that an "empty/unbound androgen receptor" is the worst thing as far as glucocorticoid signalling - and that even androgen antagonists interacting with the androgen receptor can reduce that glucocorticoid signalling." https://raypeatforum.com/community/threads/panquinone-liquid-triquinoyl-quinone-mix-for-lab-r-d.11566/page-8#post-292585
  • stagS

    Zonulin and its Consequences

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    stagS
    @LucH That's a very comprehensive paper, thanks for sharing! I didn't mean that zonulin is a protective inhibitor, I was referencing that substances that inhibit zonulin (like Larazotide acetate) are protective against its deleterious effects (like type 1 diabetes / celiac), as elaborated on in the papers we have both posted. @LucH said in Zonulin and its Consequences: For me zonulin is secreted in presence of excess lectins and gliadin (agglutinin family) to avoid aggregation with L-glutamine from the membranes. Zonulin acts as a garde-barrière, telling the body to let the toxins get away. Zonulin tells the tight junctions to stay open … Do you have more info on this? A search for lectins and leaky gut discloses this article: Lectins: The Gluten-Lectin-Leaky Gut Connection Some lectins that we consume in everyday foods can bind to the sugars in the cell walls of the gut or in the blood. This can cause an immune response, leading to inflammation, intestinal damage, altered gut flora, malabsorption, decreased cellular repair, cellular death, and eventually disease. These lectins bind to glycoproteins and glycolipids (sugar-coated proteins and fats) found on the surface of human and other animal cells. This binding allows for agglutination (clumping) and sometimes can produce an immune response. They can cause agglutination of blood cells and they can bind to the cells that line the small intestine. This article also references Fasano, he seems to be a popular guy in zonulin world. The relevant reference regarding lectins is here (I think): Dietary lectins are metabolic signals for the gut and modulate immune and hormone functions A related paper is here: Characteristics and consequences of interactions of lectins with the intestinal mucosa Following general Peat diet suggestions will have you avoiding most lectin-containing foods anyway, but there are two that stick out: dairy and nightshades. Someone could be getting most of their calories from milk and potatoes thinking theyre fine because its Peaty but may be driving intestinal permeability due to the lectin content. The example given in the article of a noxious lectin is wheat germ agglutinin. I wonder how bad non-wheat derived lectins like those from potatoes and milk are. If the mechanism is as described I also wonder if it may be advisable to keep dietary gluten and lectins to a minimum during L-glutamine supplementation, as that combination may provide ample reason for a zonulin trigger. This will be easy for wheat, likely also potatoes, but cutting milk may prove to be a challenge, if necessary. It also may be the case that the supraphysiological doses of glutamine generally used in supplementation may override any zonulin signaling caused by incidental dietary lectins. I'm not sure.
  • the MOUSET

    thoughts on this vid from foid saying seed oil harmless

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    LetTheRedeemedL
    Lol bling became cool last second. Rip
  • M

    Marijuana as an Intestinal Anti-inflammatory

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    ?
    look up cannabis hypermesis syndrome to find out what happens to some people after long term marijuana smoking.
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  • cs3000C

    This topic is deleted!

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  • ?

    3 liters of whole milk a day

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    AndrosclerozatA
    @Cezar4911 also I got a powerful warmth that was uncomfortable, similar to high protein meal
  • U

    Pregnenolone's impact on a woman's cycle?

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    U
    @FOR-THE-POTATO This is off topic....
  • the MOUSET

    thoughts? debloating, aldosterone and acne

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  • bradB

    Suppression of Haidut's Cancer Cure

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    ChudC
    @the-MOUSE you dont really need hair once your his age and already have wife/kids. and being built like that is peaty. also 1.5 liters chocolate ice cream/day diet cures hairloss but you need to supp bicarb, sunbathe, and do nofap for it to take effect.
  • W

    Taking zinc/copper/selenium and iodine for thyroid

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  • NomanarchN

    Rate the Supplement Stack of a Canadian Peater

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    PrinceTrebataP
    @Nomanarch A large amount of peaters I meet online either here or on the RPF are from Canada including me. It's interesting because I would think for our size it would be much rarer to see a Canadians on here. To answer your question though all the substances you use are good and peaty but it can be excessive if your taking them everyday. t3 and t4 are easily acquired via meds.com.mx. I had no problems getting mine through customs. Besides that ensuring you have adequate carb intake, salt to taste, eating gelatinous foods. Some other supplements you can think about trying in the future are Progest e, Pregnenolone, and Cyproheptadine.
  • Purp1eOneP

    Protein synthesis / net carbs

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    Purp1eOneP
    @Jennifer said in Protein synthesis / net carbs: “*Protein: (about 15-20% calories) .6-.8g/lb. Protein should be on the higher end if you are active, or you are older. Protein sources should be from ruminant meat (beef, bison, lamb, goat), specific seafood (shrimp, scallops, cod, sole, oysters, mussels, clams), pasture raised eggs, very lean 99% chicken/ turkey/ fowl (These are very lean because they are high in polyunsaturated fats if not).” I am older and active to I try to get 1g/lb. Like I mentioned in an earlier post when I dropped the protein intake below that my recovery suffered but that was with lower carbs so now that I am increasing them I will adjust and see how it works. I only track animal based protein in crono and disregard the plant based. @Jennifer said in Protein synthesis / net carbs: Since you developed allergies and digestive issues following a keto(ish) elimination diet and feel better since upping your carbs, I wonder if your thyroid was affected. Have you tracked your temps and pulse rate first thing in the morning and 20–30 minutes after eating? Too much protein relative to your needs and not enough carbs can lower thyroid function, and poor thyroid function is a common cause of allergies. I never had any thyroid problems until I did the lower carb diet. I did lab work while I was on that diet and my free T3 crashed but as soon as I increased the carbs it came right back to upper levels and that was just around 120 carbs. Definitely affected my thyroid. Unfortunately I had food allergies before starting that diet. I have had to avoid shell fish for quite some time now. But the EoE and possibly related to dairy/eggs could be the supps she has me on or my gut is now so messed up that will be need to be corrected. Would be nice if it was one of the supplements. Good thing is I am rotating off of some of the supps she has had me on for a year now and that is in the time frame EoE appeared. Something I will need to watch, thanks.
  • the MOUSET

    oxidised fish oil experiment

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    Milk DestroyerM
    @the-MOUSE That does seem to be what a couple of people that did hardcore Peating are saying. I can't say whether it is or not as the only time I was supplementing with lots of omega-3 was when I was also on a shit diet and the omega-3 didn't seem to help the shit diet.
  • cs3000C

    L-proline supplementation is very protective in K pneumoniae pneumonia (common in hospitals, resistant to antibiotics)

    proline infection bacteria pneumonia
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    DavidPSD
    The Multifaceted Roles of Proline in Cell Behavior Herein, we review the multifaceted roles of proline in cell biology. This peculiar cyclic imino acid is: (i) A main precursor of extracellular collagens (the most abundant human proteins), antimicrobial peptides (involved in innate immunity), salivary proteins (astringency, teeth health) and cornifins (skin permeability); (ii) an energy source for pathogenic bacteria, protozoan parasites, and metastatic cancer cells, which engage in extracellular-protein degradation to invade their host; (iii) an antistress molecule (an osmolyte and chemical chaperone) helpful against various potential harms (UV radiation, drought/salinity, heavy metals, reactive oxygen species); (iv) a neural metabotoxin associated with schizophrenia; (v) a modulator of cell signaling pathways such as the amino acid stress response and extracellular signal-related kinase pathway; (vi) an epigenetic modifier able to promote DNA and histone hypermethylation; (vii) an inducer of proliferation of stem and tumor cells; and (viii) a modulator of cell morphology and migration/invasiveness. We highlight how proline metabolism impacts beneficial tissue regeneration, but also contributes to the progression of devastating pathologies such as fibrosis and metastatic cancer.
  • ?

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  • PrinceTrebataP

    Best Soda?

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    Ray Van WinkleR
    Wallmart has jarritos now, i get it delivered every week
  • ?

    Does t3 reduce facial bloating?

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    B
    @PrinceTrebata This morning I was 97.1 with 60 pulse. I tend to wake up a bit puffy, feet kinda swole feeling, face lacking color like not much circulation, bit stuffy nosed. I was 99.2 the evening before this. After eating and little walk I get my metabolism and temps back up to a good level and feel good. I’ve been over the adrenaline hump since ramping up to this dose over the past few months taking it slow this time. I’ve never done any blood tests but I take vitamin D daily
  • Mike_FaveM

    Struggling on the Ray Peat Diet?

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    P
    I couldn't do average grocery store orange juice from unripe oranges. I don't tolerate oranges well in general. No problem with sugar and milk though. The ideal Ray Peat diet is cherimoyas and gelatin, lobster and Italian cheese as he said in the back of a tiger interview. Milk and orange juice are least bad while economical. Orange juice instead of whole oranges cause Ray had an allergy to orange fiber.