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  • Scientific papers, books, blog posts. Discussion of whatever you find interesting and notable.

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    MossyM
    @lobotomize I'm guessing you're aware of the discussion about K2 (mk4) potentially causing hair loss for some. I'm also guessing you've had no problem with that, or you would've mentioned it. Of all the vitamins being talked about, B5 and K2 are probably the ones I've heard most related to hair loss. It may help @secondkelping and others to know.
  • Websites, newsletters, articles, podcasts, interviews, explainers, books, and other resources that relate to the work of Dr. Raymond Peat.

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    C
    Cancer Treatments – from Research to Application MCS Foundations for Life, In memory of my dear wife Mihaela Catalina Stanciu https://www.cancertreatmentsresearch.com/ https://jeffreydachmd.com/cancer-articles/
  • Do you have a question? You can post it here, but you will only receive unqualified personal opinions and NOT medical advice in any shape or form. If something seems like medical advice but it's posted in this category, it's actually a personal opinion.

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    H
    @Harlock you don't have any "unforeseeable" shutdown concerns with topical DHT? especially since you're applying it to your nether region?
  • From medical devices to supplements. Red lights, CO2 tanks, large trash bags, kuinone, and more.

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    JWayneJ
    @wester130 I doubt that will feel anything from DHEA and progesterone at that dose. But the exemestane is potent enough to have an effect. All you can do is try and see what produces the most benefits for you. The good news is that even if you think you made a mistake (which at these very low doses is not really a concern), your hormones will stabilize within a few days. For instance, I've taken 400mg pregnenolone and 50mg DHEA and 12.5mg exemestane and didn't experience anything wild. I've also taken various doses of exemestane without DHEA/pregnenolone/progesterone. Any low estrogen symptoms go away within 1-3 days of ceasing A.I. administration.
  • Recipes, food, meal prep, brands. Discuss them all here.

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    MossyM
    @Jennifer said: I know the feeling. I was that kid too, needing to go to the library as a child.  I did the same, but my library sounds like an outhouse compared to the one you had.   Yours sounds like out of an old book itself; or a movie.  I probably would've enjoyed just the library itself, as much as the books, as a kid, if I had yours.  I definitely remember Silverstein.  Where the Sidewalk Ends is probably the most popular one.  The illustrations of books were just as interesting to me as well; just as much as the story.  Maurice Sendek comes to mind for illustrations.  Richard Scarey as well.  And of course, Dr. Seuss.  As a kid, I thought Where the Wild Things are was a little weird, but interesting; as an adult, I still like his illustration style very much.  My avatar is one of his drawings. I think you're right, about my body attempting to tell me something about supplements.  I could guess many, if not most, are worse than ever; being sourced out of country, for as cheaply as possible. But, maybe there still are some good ones left.  Like that Doctor's herbs you recommended to me a while back.  I'm looking for an all-in-one, or something similar, for my dad.  To see how he does with, several times a week.  And maybe for myself, thought I know it's not too likely I can take it with any regularity. I couldn't agree more.  I am so skeptical of doctors after my experiences, I do everything to avoid them.  Haha...good idea about your limbs.  I too am convinced, we are best tuned to our own body, and if we have any inkling and interest in self-treatment, it's worth a try.  But, after about 15 years of dabbling in self-treatment, I know I'm limited in what I can understand and do. Interesting how your metabolic rate is related with your stress-resistance.  That makes sense, and I'd say it correlates for me as well.  I would imagine taking thyroid a big contributor in that: are you still doing that?  Also interesting about the small cecum, how it doesn't like roughage, which jives with my experience when at my worst, and even still.  Even the raw carrot can be hard on my system; so much so, that I've stopped taking it. I'll probably start back again soon. Thanks for the links.  I have been buying Thomas's, which are hard to beat taste wise.  I did used to buy Food for Life bread, quite some years back, which I thought was hearty and healthy, though not light and fluffy, like we're used to. Maybe I'll try their English muffins one of these times. That's funny the Painter Sister's was tart for you.  I've only had the vanilla, so it wasn't tart for me at all.  I think the plain would be.  Ok, good information you've passed along from Ray about dairy.  Thank you.  I don't know why I didn't put that together, that Ray was wanting to avoid PUFA, with the lower fat dairy.  I had forgotten that it even had PUFA.  I've really toned down my hyper-vigilance with regard to diet and number crunching, but I do think there is obvious necessity to it.  So you're one of the lucky ones—you do well on high fat dairy.  I do eat it for some items, like the yogurt, but I do think I do better with lower fat over all; at least for now. Indeed, the baby golds are good!  I've made yet another batch of potato salad a few days ago.  It blows my mind how time intensive recipes are.  I think I'm the problem, though.  I know many cooks can sleep walk in the kitchen, and get the recipe done in half the time I can.
  • Discussing pistol squats, concentric exercise, resting, and other forms of strength training.

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    engineerE
    Earlier this year I was taking a lot of exogenous T isocaproate (4d half life ester) and stopped. However, before then and after, I was also taking exemestane (aromasin) which led to the recovery being basically instant. Actually, with how big and "meaty" my balls were after stopping, I'm inclined to say my natural production INCREASED afterwards compared to before taking exogenous T.
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    yerragY
    @CrumblingCookie said in Normal body temperature is now 97.9. "it’s rarely as high as 98.6 F": s it just PUFA? Is it an altered setpoint of carbohydrate/caloric malnutrition? Is it electromagnetic interference of physiological cellular functioning? Is it a (low-key) chronic disease state? PUFA is one key reason. The more PUFA and the less SFA the fat being used as a substrate in fatty acid metabolism, the more likely the mitochondria is deprived of co-factors it needs to run on sugar-based mitochondrial metabolism. Sugar metabolism becomes cytosolic and glycolytic, which produces much less energy. More lactic acid is produced and less CO2. Less energy already makes for lower temperature. But it gets worse when the body has less available CO2. Because enough CO2.is needed in the blood to effect adequate tissue oxygenation of our cells and tissues. Without enough oxygen in the tissues, the body will keep on producing energy inefficiently by producing energy from sugar glycolytically, and become more dependent on fatty acid mitochondrial metabolism, the mitochondrial pathway throttled as it is on oxygen being limited already. The combined capacity of the mitochondria and the cytoplasm to produce energy will be much less, and this would be reflected in lower temperatures across the board. Last year my lungs had bronchitis and I was not getting enough oxygen from breathing. At that state, and unaware of the effect of has, I dove in my fishpond to clear some debris from the bottom. I got hypothermia from it. I was shivering a lot, and struggled to come up. My temperature has gone down to 35C in less than a minute.
  • Raymond on L-Theanine

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    CearrsonC
    @LucH Great stuff thank you.
  • DNP in ethanol

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    M
    @grymsky90210 Lol thanks. I have lost some weight. Not sure it's because of the DNP tho. I have dosed it very sporadically. Mostly just used it on cold nights to stay warm but not even sure I have even felt those effects much. I thought ethanol would enhance it's effects but hasn't been the case for me. But this was by no means a perfect experiment. Did not take it regularly and am very likely underdosing.
  • Progest-E as a contraceptive.

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    SunnivaS
    It would be vaginally. I think the idea is that while pregnant, the body ramps up progesterone to support pregnancy. Using vaginally is to make the body think it is already pregnant, and therefore would not have need for another implantation. Ray Peat spoke about this in an interview.
  • Topical Vitamin K2 for regrowth

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    T
    @onliest thnaks, never heard of this, but then again I'm in Europe...I will have to mix it myself since they don't ship overseas.
  • What to do about Orange Juice causing high histamine?

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    LucHL
    @sneedful said in What to do about Orange Juice causing high histamine?: dates dont have high oxalates, the exact info is available from studies. I have several sources mentioning no oxalates and other "respectful" ones (4x) mentioning the contrary. I can post if you're receptive And why : Oxalates are natural compounds found in vegetables, fruits, nuts, and grains. This inhibiting effect is due to the binding functions of antinutrients in plants in order to protect the species: If the animals eat too much of them, the natural cycle would be stopped.
  • Vitamin E safe for daily consumption?

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    DavidPSD
    Peatbot: Yes, vitamin E has undergone significant changes over the years. Originally, vitamin E was produced using methods that resulted in a product that was thick, viscous, and often brown in color. This form of vitamin E was associated with beneficial effects, including anti-estrogenic and anti-clotting properties, and was thought to protect against the toxic effects of polyunsaturated fatty acids (PUFAs). However, over time, the manufacturing processes for vitamin E have changed. For example, when ADM bought the old Eastman distillation products factory, they altered the methods of production, which affected the consistency and appearance of vitamin E. The newer vitamin E products became more diluted, often with soybean oil, which is highly unsaturated. This change in formulation has been linked to a reduction in the beneficial effects that were observed with the original vitamin E products. Additionally, the perception and definition of vitamin E's role have evolved. Initially, it was recognized for its fertility-enhancing and anti-estrogenic properties, but later it was primarily marketed as an antioxidant. The changes in manufacturing and formulation have led to variations in the effectiveness and safety of vitamin E supplements, with some studies suggesting increased mortality associated with certain formulations. Overall, the form and quality of vitamin E have shifted, and these changes have influenced its perceived health benefits and risks. Peatbot: Yes, vitamin E is generally considered safe to take on a daily basis, especially when taken in appropriate amounts. The context suggests that about 30 to 50 milligrams per day can provide full protection. However, it's important to choose a high-quality vitamin E supplement, preferably one that contains mixed tocopherols, as these are anti-inflammatory. It's also noted that vitamin E is particularly beneficial if you are consuming polyunsaturated fatty acids (PUFAs), as it can help counteract some of their negative effects.
  • This topic is deleted!

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    serotoninskepticS
    @LetTheRedeemed Yea ray also said that thyroid is unstable dissolved in alcohol I believe
  • What is your favourite substance/ supplement for reducing cortisol?

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    LetTheRedeemedL
    @Jennifer said in What is your favourite substance/ supplement for reducing cortisol?: Ice cream. based
  • Does anyone here use greek unipharma t3?

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  • T3 hell yeah

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    ?
    @Kvirion underground steroid sites almost always sell T3 since it's popular in their sphere Unipharma is from greece and actually pharmagrade,you have to search for a trusted brand
  • Best country/location to live in

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    ?
    @White Do you have no friends? No family? Remote income? In that case, you ought to travel and see for yourself the corners of the world. See what appeals to you with your own eyes. Then consider whether to settle down there and set down roots.
  • whats your opinion on taking kefir?

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    yerragY
    @RawGoatMilk88 That one is good. Mike Fave recommended that to me as well.
  • Share positive experiences with eating liver

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    serotoninskepticS
    @yerrag Haha thats a funny dtory I hope its true
  • T3 vs Aspirin (for fatigue)

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    serotoninskepticS
    @James T3 works better for fatigue in my experience. Aspirin doesnt have notable effects on my energy
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    serotoninskepticS
    @the-MOUSE Lundberg's Basmati White Rice tests the lowest in arsenic. White rice is your best bet for grains
  • How should serotonin depletion feel like?

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    D
    Also I remember reading something about how tyrosine is converted to dopamine (which will drop serotonin) when sunlight is directed at the scalp so get some sun to improve your results.
  • Milk fat

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    J
    @RawGoatMilk88 In what way is skim milk nutritionally devoid? It doesn't contain much in terms of fat soluble vitamins but it still has plenty of b12, b2, calcium, ect and is a good protein source
  • friends, what do you think about Methyluracil?

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