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  • Scientific papers, books, blog posts. Discussion of whatever you find interesting and notable.

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    chudlordC
    @jamezb46 is it not more likely that this is merely increased excretion rather than increased absorption?
  • Websites, newsletters, articles, podcasts, interviews, explainers, books, and other resources that relate to the work of Dr. Raymond Peat.

    62 Topics
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    Cancer Treatments – from Research to Application MCS Foundations for Life, In memory of my dear wife Mihaela Catalina Stanciu https://www.cancertreatmentsresearch.com/ https://jeffreydachmd.com/cancer-articles/
  • Do you have a question? You can post it here, but you will only receive unqualified personal opinions and NOT medical advice in any shape or form. If something seems like medical advice but it's posted in this category, it's actually a personal opinion.

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    HarlockH
    Gm guys! I got cold urticaria when I am in contact with cold water, cold air, anything cold. Beside bad thyroid, what do you think could be the cause? Cypro works well but puts me in a really tired state that I can't afford. Thx a lot guys! [image: 1789697110092-whatsapp-image-2026-09-18-at-02.52.27.jpeg] [image: 1789697118682-whatsapp-image-2026-09-18-at-02.53.48.jpeg]
  • From medical devices to supplements. Red lights, CO2 tanks, large trash bags, kuinone, and more.

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    I was told, "Turkey tail mushroom powder is a ground dietary supplement made from the Trametes versi-color fungus, widely used to support immune function and gut health. The Japanese use this for cancer" Does anyone know anything about this? Being given to a pooch diagnosed with leukemia. Thanks
  • Recipes, food, meal prep, brands. Discuss them all here.

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    JenniferJ
    @Mossy, exactly, and for me, love is the main component—in practice, basing my choices on a love for myself (and others by extension—man being a strand in the web of life and all) and my life, not fear, has proven to be the most healing of all. I believe there is no higher vibration than God and God is love. Thank you for sharing The Four Loves with me. I found a free pdf of it on archive.org and am currently reading it. I had never read anything by C. S. Lewis before, but I was aware he was a Christian apologist so I had some idea of what to expect—I’m not Christian, myself, but having grown up in a Catholic family and attended parochial school, I’m familiar with the Christian concept of God. I think cold can have an effect on an egg’s cloudiness, too, because I’ve had cartons of eggs too close to the refrigerator’s fan that partially froze, and the half that froze and defrosted had very cloudy whites. It’s too bad you can only get the Nounós at Whole Foods. I’ve only found two stores here that carry it. If you can get your hands on Alexandre Family Farm’s whole milk yogurt and strain it, it’s similar. I used to strain the Alexandre’s, but it became too costly at $7.99 for a 24 oz container (roughly 12 oz after straining) daily. For comparison, I paid $5.99 for a 16 oz container of Nounós. No worries. I knew exactly what you meant by mushroom. I should clarify that my experience is not a reflection of the quality of lichen-based D3, but my health status, at the time. My thyroid was still recovering from the trauma of my mum’s passing and for whatever reason, when my thyroid tanks, I struggle with plants so practically everything plant-based was causing hives. I haven’t tried Haidut’s vitamin D, only because I like to take D3 orally for best absorption and don’t care for ethanol, but I appreciate that it doesn’t contain MCT, for those whose intestines would be irritated by it. Have you tried D3 in a base of olive oil? I’m wondering if you would be less sensitive to that excipient? Haha! I take no offense. As a recovering perfectionist, I understand neuroticism well and besides, you’re Italian so I trust your judgment. Now, if you try schooling me on butter, those are fighting words, mister. JK I bring my people shame—I don’t eat butter. Mayo is my dad’s condiment of choice for sandwiches and he doesn’t like the coconut-based one, due to it solidifying in the fridge and needing to take it out in advance to soften it before use, which he doesn’t have the patience for, so I figure the Graza is a good compromise. What type of olive oil do you prefer? I get my dad the “fancy” made with 100% extra virgin olive oil. Is extra virgin not good? While growing up, my mum used mainly butter in her cooking and evoo in her baking—she did cake decorating and swore by oil for moist cakes—so that’s my only reference point.
  • Discussing pistol squats, concentric exercise, resting, and other forms of strength training.

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    alfredoolivasA
    @PrinceTrebata very ho behaviour not replying. Sorry. I stopped the back ones and still don’t do them( I am still catabolic! Not getting stronger in the gym! Back aches! Bone hurts!) despite getting more than enough protein. This is perfect btw. I am not trying to be anabolic, as that usually entails with some sort of fat growth or water retention from AAS. But that’s a different story more suited for the moggy chicken Currently have been and am doing high seat biking. If I recover (hopefully when I slowly ramp up the calories), and those issues go away, I’ll throw in the stretches and stretching machine. If I find a sustainable routine with time.
  • How to come off of thyroid supplementation?

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    serotoninskepticS
    @mavuue Hmm i guess you could experiment with coming off. It would only take like 2 weeks max for natural thyroid function to re ignite
  • Does anyone take a multivitamin? What to look for in it?

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    LucHL
    @BioEclectic said in Does anyone take a multivitamin? What to look for in it?: interesting note about the B50 complex. I recall you mentioning before but i don't recall the backup detail (?) That potentially harmful? AMPK sensor: Friend or foe? @BioEclectic Starting point: Too much of a good thing can become counterproductive (cancer). BioEclectic, a forum user on bioenergetic.com, recently asked me why it was not appropriate to regularly take a complex Vitamin B50 supplement. OK if it's 2x/week or these are the RDA if taken regularly, knowing that we will then have chosen a co-enzymated form (with cofactors), without yuck ingredients. (…) Short answer: AMPK functions as an energy sensor in our cells. This sensor plays a key role in the balance between anabolic and catabolic programs for cellular homeostasis in response to metabolic stress. In the case of a tumor, the cancer cell attempts to slow down oxidative metabolism and works to divert the supply of glucose for its own benefit in order to grow. The cancer cell will therefore try to down-regulate the influence of AMPK, which acts a little too much like a traffic agent to supply the different organs, instead of promoting the flow of fuel to the advantage of his own needs. So, what the link with cancer? Taking high dose of thiamin (B1) or pyridoxine PLP (B6) – they are just 2 examples of antioxidant – they act to moderate the AMPK sensor, to dampen the effects. Right in cure or if the dose turns round RDA but not for prolonged use. Reactive oxygen species (ROS) are continuously produced as a by-product of mitochondrial metabolism and eliminated via antioxidant systems. Cancer cells try to moderate / neutralize anti-stress. Full answer on my forum, with link in English and in French (translator needed). Cancer cells are usual, at a certain age, and have to be considered “normal” if the size does not exceed a €2 coin… AMPK as a regulator of energy metabolism How much B vitamins do we need, in which proportions? How can we modulate the sensitivity of the regulation? Cancer cells divert the supply of fuel and try to avoid oxidative stress. What’s the link between B1 and cancer growth? Targeting the AMP-Activated Protein Kinase for Cancer purpose?
  • Am I retarded?

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    GardnerG
    Ray, "The prenatal growth retardation that can be caused by feeding large amounts of caffeine is prevented by supplementing the diet with sugar". Sugar is a holy pill.
  • mood swings / irritability cures

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    @raytreats I eliminated my chronic anger with dextrose. I am more resilient to stress than I have ever been in my adult life.
  • Ray Peat Social Club in Austin, TX

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    herayclitusH
    A meetup is definitely a great idea, kudos for putting this together
  • Prevent metabolic damage in extreme caloric deficit

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    You'll want plenty of Vitamin E to protect from the fat you are releasing as you lose weight. I also love theanine after workouts. It helps to reduce serotonin and estrogen. I prefer 0.7g protein per pound of your target bodyweight. It would help to know how heavy you are now and what you plan to do to lose the weight. You should avoid steady-state cardio except as walking. I would do HIIT sessions on an exercise bike 3x/wk and lots of walking. Walking outside will do the most for you but in the gym you should walk at a steep incline on the treadmill to burn the most calories. You'll want to keep your muscle until close to you weigh-in date, but high reps will push more fluid into them without boosting their metabolic rate. Stick to 1-3 reps per set.
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    yerragY
    @CrumblingCookie said in Normal body temperature is now 97.9. "it’s rarely as high as 98.6 F": s it just PUFA? Is it an altered setpoint of carbohydrate/caloric malnutrition? Is it electromagnetic interference of physiological cellular functioning? Is it a (low-key) chronic disease state? PUFA is one key reason. The more PUFA and the less SFA the fat being used as a substrate in fatty acid metabolism, the more likely the mitochondria is deprived of co-factors it needs to run on sugar-based mitochondrial metabolism. Sugar metabolism becomes cytosolic and glycolytic, which produces much less energy. More lactic acid is produced and less CO2. Less energy already makes for lower temperature. But it gets worse when the body has less available CO2. Because enough CO2.is needed in the blood to effect adequate tissue oxygenation of our cells and tissues. Without enough oxygen in the tissues, the body will keep on producing energy inefficiently by producing energy from sugar glycolytically, and become more dependent on fatty acid mitochondrial metabolism, the mitochondrial pathway throttled as it is on oxygen being limited already. The combined capacity of the mitochondria and the cytoplasm to produce energy will be much less, and this would be reflected in lower temperatures across the board. Last year my lungs had bronchitis and I was not getting enough oxygen from breathing. At that state, and unaware of the effect of has, I dove in my fishpond to clear some debris from the bottom. I got hypothermia from it. I was shivering a lot, and struggled to come up. My temperature has gone down to 35C in less than a minute.
  • Raymond on L-Theanine

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    CearrsonC
    @LucH Great stuff thank you.
  • DNP in ethanol

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    @grymsky90210 Lol thanks. I have lost some weight. Not sure it's because of the DNP tho. I have dosed it very sporadically. Mostly just used it on cold nights to stay warm but not even sure I have even felt those effects much. I thought ethanol would enhance it's effects but hasn't been the case for me. But this was by no means a perfect experiment. Did not take it regularly and am very likely underdosing.
  • Progest-E as a contraceptive.

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    SunnivaS
    It would be vaginally. I think the idea is that while pregnant, the body ramps up progesterone to support pregnancy. Using vaginally is to make the body think it is already pregnant, and therefore would not have need for another implantation. Ray Peat spoke about this in an interview.
  • Topical Vitamin K2 for regrowth

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    @onliest thnaks, never heard of this, but then again I'm in Europe...I will have to mix it myself since they don't ship overseas.
  • What to do about Orange Juice causing high histamine?

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    LucHL
    @sneedful said in What to do about Orange Juice causing high histamine?: dates dont have high oxalates, the exact info is available from studies. I have several sources mentioning no oxalates and other "respectful" ones (4x) mentioning the contrary. I can post if you're receptive And why : Oxalates are natural compounds found in vegetables, fruits, nuts, and grains. This inhibiting effect is due to the binding functions of antinutrients in plants in order to protect the species: If the animals eat too much of them, the natural cycle would be stopped.
  • Vitamin E safe for daily consumption?

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    DavidPSD
    Peatbot: Yes, vitamin E has undergone significant changes over the years. Originally, vitamin E was produced using methods that resulted in a product that was thick, viscous, and often brown in color. This form of vitamin E was associated with beneficial effects, including anti-estrogenic and anti-clotting properties, and was thought to protect against the toxic effects of polyunsaturated fatty acids (PUFAs). However, over time, the manufacturing processes for vitamin E have changed. For example, when ADM bought the old Eastman distillation products factory, they altered the methods of production, which affected the consistency and appearance of vitamin E. The newer vitamin E products became more diluted, often with soybean oil, which is highly unsaturated. This change in formulation has been linked to a reduction in the beneficial effects that were observed with the original vitamin E products. Additionally, the perception and definition of vitamin E's role have evolved. Initially, it was recognized for its fertility-enhancing and anti-estrogenic properties, but later it was primarily marketed as an antioxidant. The changes in manufacturing and formulation have led to variations in the effectiveness and safety of vitamin E supplements, with some studies suggesting increased mortality associated with certain formulations. Overall, the form and quality of vitamin E have shifted, and these changes have influenced its perceived health benefits and risks. Peatbot: Yes, vitamin E is generally considered safe to take on a daily basis, especially when taken in appropriate amounts. The context suggests that about 30 to 50 milligrams per day can provide full protection. However, it's important to choose a high-quality vitamin E supplement, preferably one that contains mixed tocopherols, as these are anti-inflammatory. It's also noted that vitamin E is particularly beneficial if you are consuming polyunsaturated fatty acids (PUFAs), as it can help counteract some of their negative effects.
  • This topic is deleted!

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    serotoninskepticS
    @LetTheRedeemed Yea ray also said that thyroid is unstable dissolved in alcohol I believe
  • What is your favourite substance/ supplement for reducing cortisol?

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    LetTheRedeemedL
    @Jennifer said in What is your favourite substance/ supplement for reducing cortisol?: Ice cream. based
  • Does anyone here use greek unipharma t3?

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  • T3 hell yeah

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    ?
    @Kvirion underground steroid sites almost always sell T3 since it's popular in their sphere Unipharma is from greece and actually pharmagrade,you have to search for a trusted brand
  • Best country/location to live in

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    @White Do you have no friends? No family? Remote income? In that case, you ought to travel and see for yourself the corners of the world. See what appeals to you with your own eyes. Then consider whether to settle down there and set down roots.
  • whats your opinion on taking kefir?

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    yerragY
    @RawGoatMilk88 That one is good. Mike Fave recommended that to me as well.