Dandruff or scalp irritation? Try BLOO.

Subcategories

  • Scientific papers, books, blog posts. Discussion of whatever you find interesting and notable.

    692 Topics
    5k Posts
    C
    And I was looking for the answer on whether FMTs are a guarantor for clearance of fungal abundance in the small intestinal or colonic lumen. Surprisingly, it's a no! It appears to be even the other way round. Here's something interesting IMO about FMTs: Gut fungal dysbiosis correlates with reduced efficacy of fecal microbiota transplantation in Clostridium difficile infection, 2018 In this study, it is shown that CDI is strongly accompanied by over-representation of Candida albicans and decreased fungal diversity, richness, and evenness. Post-FMT, successful responders lack their previous C. albicans dominance but rather display a high relative abundance of Saccharomyces and Aspergillus. High abundance of C. albicans in donor stool also correlates with reduced FMT efficacy. In essence, therefore, annihilation of Candida dominance in CDI patients is crucial for FMT success and arguable it could be much advisable to pre-/co-treat any CDI with antifungals along with either ABx or FMT. Another study showed contrasting results of FMT on UC: Fungal Trans-kingdom Dynamics Linked to Responsiveness to Fecal Microbiota Transplantation (FMT) Therapy in Ulcerative Colitis, 2020 Herein they showed that in contrast to FMT in CDI, clinically successful response to FMT in UC very much depended on high Candida abundance at baseline, which decreased after FMT. The authors argue that the prior Candida dominance may provide a specific niche for bacterial engraftment, ameliorating UC. So, the very opposite of the pre-conditions in CDI. However, what the authors do not talk about in their text but what their graphs clearly show is the following caveat: UC patients with a low relative Candida abundance at baseline did not only not clinically benefit from the FMT, but their dysbiosis, inflammation and Candida levels post-FMT was mostly even larger than before (confounders? Small sample size?): [image: 1-s2.0-S1931312820301700-fx1.jpg] [image: 1-s2.0-S1931312820301700-gr2.jpg]´
  • Websites, newsletters, articles, podcasts, interviews, explainers, books, and other resources that relate to the work of Dr. Raymond Peat.

    62 Topics
    703 Posts
    CiceroC
    I noticed the reprint of Nutrition for Women says "100 short articles by Ray Peat, PHD," where the old one said "92...". What did they add to it? Also, note that From PMS to Menopause is for sale on Peat's website but not Amazon, and Peat's website doesn't have Generative Energy. Weird. I wonder if Katherine gets more of the money if you order from Peat's site. I'd imagine so.
  • Do you have a question? You can post it here, but you will only receive unqualified personal opinions and NOT medical advice in any shape or form. If something seems like medical advice but it's posted in this category, it's actually a personal opinion.

    1k Topics
    11k Posts
    H
    @GRay interesting. if it aint broke don't fix it
  • From medical devices to supplements. Red lights, CO2 tanks, large trash bags, kuinone, and more.

    395 Topics
    4k Posts
    daposeD
    I’ve been using two drops 8mg of thymoquinone of the current formulation right before bed on my tongue. Sleeping extra good. Don’t wake up at all until alarm clock except some recent thunderstorms. I replaced 4 drops of Kuinone on tongue before bed. I like the effects of Tuinone better. More calming. For black seed oil seems like if you had an extra strength oil 7.5% TQ you’d need about a teaspoon of the product and would be getting lots of Pufa and other things that aren’t thymoquinone
  • Recipes, food, meal prep, brands. Discuss them all here.

    238 Topics
    2k Posts
    Milk DestroyerM
    @alfredoolivas Perhaps, but I'm not certain. I actually was eating a lot more kale recently (maybe 150g a day) for a week and I did notice I had lost some weight (like 5lbs), but I was also walking in nature more at the time. I'll try incorporating it more consistently and get back to you.
  • Discussing pistol squats, concentric exercise, resting, and other forms of strength training.

    95 Topics
    1k Posts
    alfredoolivasA
    @hawk1 okay you actually had agency & balls and settled with some pretty decent sources. It took you two months, but I’m proud of you if that means anything.
  • Am I retarded?

    7
    0 Votes
    7 Posts
    1k Views
    GardnerG
    Ray, "The prenatal growth retardation that can be caused by feeding large amounts of caffeine is prevented by supplementing the diet with sugar". Sugar is a holy pill.
  • mood swings / irritability cures

    9
    0 Votes
    9 Posts
    1k Views
    E
    @raytreats I eliminated my chronic anger with dextrose. I am more resilient to stress than I have ever been in my adult life.
  • Ray Peat Social Club in Austin, TX

    4
    0 Votes
    4 Posts
    444 Views
    herayclitusH
    A meetup is definitely a great idea, kudos for putting this together
  • Prevent metabolic damage in extreme caloric deficit

    11
    0 Votes
    11 Posts
    1k Views
    A
    You'll want plenty of Vitamin E to protect from the fat you are releasing as you lose weight. I also love theanine after workouts. It helps to reduce serotonin and estrogen. I prefer 0.7g protein per pound of your target bodyweight. It would help to know how heavy you are now and what you plan to do to lose the weight. You should avoid steady-state cardio except as walking. I would do HIIT sessions on an exercise bike 3x/wk and lots of walking. Walking outside will do the most for you but in the gym you should walk at a steep incline on the treadmill to burn the most calories. You'll want to keep your muscle until close to you weigh-in date, but high reps will push more fluid into them without boosting their metabolic rate. Stick to 1-3 reps per set.
  • Normal body temperature is now 97.9. "it’s rarely as high as 98.6 F"

    8
    0 Votes
    8 Posts
    703 Views
    yerragY
    @CrumblingCookie said in Normal body temperature is now 97.9. "it’s rarely as high as 98.6 F": s it just PUFA? Is it an altered setpoint of carbohydrate/caloric malnutrition? Is it electromagnetic interference of physiological cellular functioning? Is it a (low-key) chronic disease state? PUFA is one key reason. The more PUFA and the less SFA the fat being used as a substrate in fatty acid metabolism, the more likely the mitochondria is deprived of co-factors it needs to run on sugar-based mitochondrial metabolism. Sugar metabolism becomes cytosolic and glycolytic, which produces much less energy. More lactic acid is produced and less CO2. Less energy already makes for lower temperature. But it gets worse when the body has less available CO2. Because enough CO2.is needed in the blood to effect adequate tissue oxygenation of our cells and tissues. Without enough oxygen in the tissues, the body will keep on producing energy inefficiently by producing energy from sugar glycolytically, and become more dependent on fatty acid mitochondrial metabolism, the mitochondrial pathway throttled as it is on oxygen being limited already. The combined capacity of the mitochondria and the cytoplasm to produce energy will be much less, and this would be reflected in lower temperatures across the board. Last year my lungs had bronchitis and I was not getting enough oxygen from breathing. At that state, and unaware of the effect of has, I dove in my fishpond to clear some debris from the bottom. I got hypothermia from it. I was shivering a lot, and struggled to come up. My temperature has gone down to 35C in less than a minute.
  • Raymond on L-Theanine

    4
    0 Votes
    4 Posts
    2k Views
    CearrsonC
    @LucH Great stuff thank you.
  • DNP in ethanol

    11
    0 Votes
    11 Posts
    1k Views
    M
    @grymsky90210 Lol thanks. I have lost some weight. Not sure it's because of the DNP tho. I have dosed it very sporadically. Mostly just used it on cold nights to stay warm but not even sure I have even felt those effects much. I thought ethanol would enhance it's effects but hasn't been the case for me. But this was by no means a perfect experiment. Did not take it regularly and am very likely underdosing.
  • Progest-E as a contraceptive.

    2
    0 Votes
    2 Posts
    627 Views
    SunnivaS
    It would be vaginally. I think the idea is that while pregnant, the body ramps up progesterone to support pregnancy. Using vaginally is to make the body think it is already pregnant, and therefore would not have need for another implantation. Ray Peat spoke about this in an interview.
  • Topical Vitamin K2 for regrowth

    8
    0 Votes
    8 Posts
    1k Views
    T
    @onliest thnaks, never heard of this, but then again I'm in Europe...I will have to mix it myself since they don't ship overseas.
  • What to do about Orange Juice causing high histamine?

    12
    0 Votes
    12 Posts
    1k Views
    LucHL
    @sneedful said in What to do about Orange Juice causing high histamine?: dates dont have high oxalates, the exact info is available from studies. I have several sources mentioning no oxalates and other "respectful" ones (4x) mentioning the contrary. I can post if you're receptive And why : Oxalates are natural compounds found in vegetables, fruits, nuts, and grains. This inhibiting effect is due to the binding functions of antinutrients in plants in order to protect the species: If the animals eat too much of them, the natural cycle would be stopped.
  • Vitamin E safe for daily consumption?

    10
    0 Votes
    10 Posts
    1k Views
    DavidPSD
    Peatbot: Yes, vitamin E has undergone significant changes over the years. Originally, vitamin E was produced using methods that resulted in a product that was thick, viscous, and often brown in color. This form of vitamin E was associated with beneficial effects, including anti-estrogenic and anti-clotting properties, and was thought to protect against the toxic effects of polyunsaturated fatty acids (PUFAs). However, over time, the manufacturing processes for vitamin E have changed. For example, when ADM bought the old Eastman distillation products factory, they altered the methods of production, which affected the consistency and appearance of vitamin E. The newer vitamin E products became more diluted, often with soybean oil, which is highly unsaturated. This change in formulation has been linked to a reduction in the beneficial effects that were observed with the original vitamin E products. Additionally, the perception and definition of vitamin E's role have evolved. Initially, it was recognized for its fertility-enhancing and anti-estrogenic properties, but later it was primarily marketed as an antioxidant. The changes in manufacturing and formulation have led to variations in the effectiveness and safety of vitamin E supplements, with some studies suggesting increased mortality associated with certain formulations. Overall, the form and quality of vitamin E have shifted, and these changes have influenced its perceived health benefits and risks. Peatbot: Yes, vitamin E is generally considered safe to take on a daily basis, especially when taken in appropriate amounts. The context suggests that about 30 to 50 milligrams per day can provide full protection. However, it's important to choose a high-quality vitamin E supplement, preferably one that contains mixed tocopherols, as these are anti-inflammatory. It's also noted that vitamin E is particularly beneficial if you are consuming polyunsaturated fatty acids (PUFAs), as it can help counteract some of their negative effects.
  • This topic is deleted!

    3
    1
    0 Votes
    3 Posts
    32 Views
  • Is tyronene from idealabs(taken orally) just as effective as cynomel?

    6
    0 Votes
    6 Posts
    1k Views
    serotoninskepticS
    @LetTheRedeemed Yea ray also said that thyroid is unstable dissolved in alcohol I believe
  • What is your favourite substance/ supplement for reducing cortisol?

    13
    0 Votes
    13 Posts
    1k Views
    LetTheRedeemedL
    @Jennifer said in What is your favourite substance/ supplement for reducing cortisol?: Ice cream. based
  • Does anyone here use greek unipharma t3?

    1
    0 Votes
    1 Posts
    152 Views
    No one has replied
  • T3 hell yeah

    6
    1
    0 Votes
    6 Posts
    563 Views
    ?
    @Kvirion underground steroid sites almost always sell T3 since it's popular in their sphere Unipharma is from greece and actually pharmagrade,you have to search for a trusted brand
  • Best country/location to live in

    5
    0 Votes
    5 Posts
    753 Views
    ?
    @White Do you have no friends? No family? Remote income? In that case, you ought to travel and see for yourself the corners of the world. See what appeals to you with your own eyes. Then consider whether to settle down there and set down roots.
  • whats your opinion on taking kefir?

    20
    0 Votes
    20 Posts
    2k Views
    yerragY
    @RawGoatMilk88 That one is good. Mike Fave recommended that to me as well.
  • Share positive experiences with eating liver

    26
    0 Votes
    26 Posts
    3k Views
    serotoninskepticS
    @yerrag Haha thats a funny dtory I hope its true
  • T3 vs Aspirin (for fatigue)

    3
    0 Votes
    3 Posts
    416 Views
    serotoninskepticS
    @James T3 works better for fatigue in my experience. Aspirin doesnt have notable effects on my energy