@sphenoid said in Thiamine almost fixed my chronic symptoms.:
I’m having a hard time understand how sugar “cancels out” thiamine. Doesn’t just this mean thiamine will be used to metabolize the sugar? Same with caffeine.
I got that info from the FAQs on Dr. Costantini's website. But from my own experience, I believe it to be true. I think the problem happens when the sugar and the thiamine are in the stomach at the same time.
About Dr. Costantini (from the link above):
"He is a neurologist in Viterbo, Italy with his own practice and 2,700 + patients that he is treating with thiamine as an adjunctive treatment to their standard PD meds. He has been treating his patients with PD for over 5 years now during which time no apparent disease progression has been observed while symptom improvement has been significant for most patients.
"As far as thiamine, he has been working with it since 2010/2011.
"He said that even if they couldn’t come to his clinic, he could still try to treat them via email. He said he needed a copy of their medical records and short videos of a Pull Test, of them talking, writing and a short video of them walking."
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Unfortunately, he died in 2020. I believe that he had more experience actually treating people using high dose thiamine hcl than anyone else. His research papers are here. I take thiamine hcl since I was unable to tolerate TTFD thiamine (the favorite of Dr. Lonsdale and Elliot Overton) because my glutathione level was very low. So I've relied on Dr. Costantini's clinical experience that is shared on his website. I value Dr. Lonsdale's and Elliot Overton's articles and videos as the information is pertinent to supplementing with high dose thiamine hcl too.
I should also say that Dr. Lonsdale and Elliot Overton and Dr. Chandler Marrs all talk about TTFD's "paradoxical" reaction which is negative side effects from taking TTFD that some patients "have to work through". In contrast, Dr. Costantini said that there should not be any negative symptoms from taking thiamine hcl and if that happened (rarely), he would take the patient off the treatment for a week and then resume with a dose half the amount as what caused the problem.
My husband takes 200mg of TTFD/day and has never had any problem from taking it.