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  • Scientific papers, books, blog posts. Discussion of whatever you find interesting and notable.

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    yerragY
    @Ena said: Yes, statins possess antibacterial properties, so in principle they will introduce LPS by helping the white blood cells to kill bacteria. But it's a strange wording, so I don't understand what he means either. @Ena said: Yes, statins possess antibacterial properties, so in principle they will introduce LPS by helping the white blood cells to kill bacteria. But it's a strange wording, so I don't understand what he means either. I think so too. Stating are antibacterial though they are not marketed to be anything else but a cholesterol lowering drug. Otherwise why would they lead to increasing endotoxins.
  • Websites, newsletters, articles, podcasts, interviews, explainers, books, and other resources that relate to the work of Dr. Raymond Peat.

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    CiceroC
    I noticed the reprint of Nutrition for Women says "100 short articles by Ray Peat, PHD," where the old one said "92...". What did they add to it? Also, note that From PMS to Menopause is for sale on Peat's website but not Amazon, and Peat's website doesn't have Generative Energy. Weird. I wonder if Katherine gets more of the money if you order from Peat's site. I'd imagine so.
  • Do you have a question? You can post it here, but you will only receive unqualified personal opinions and NOT medical advice in any shape or form. If something seems like medical advice but it's posted in this category, it's actually a personal opinion.

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    W
    @ChroncStresChris yes generally speaking, because DHT dries you out and may actually reduce tesosterone testosterone is "wet" and is needed with dht, dht is "dry"
  • From medical devices to supplements. Red lights, CO2 tanks, large trash bags, kuinone, and more.

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    M
    @disfrutarlo I inquired of six different vendors of the same requesting heavy metal analysis every company responded, except Great Lakes. I called them. They refused to give the information.
  • Recipes, food, meal prep, brands. Discuss them all here.

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    JenniferJ
    @Mossy, do you mean the brand or type of French bread like the baguette? I was trying to think of popular French brands, but couldn’t come up with any. That’s great! My grandmother used red potatoes too for her potato salad. Aside from digestibility—baby potatoes typically being easier to digest—the best potato really depends on its growing conditions and less so the variety, IME. After spending months testing numerous varieties from different suppliers, I (happily) settled on the baby Yukons. They’re from a local supermarket chain and even better than the Upstate Abundance—they’re consistently so creamy and flavorful that they don’t need any added butter or salt, but they’re half the price and available year round. Alexandre is excellent, yes, but prior to caring for my dad, the majority of my dairy (and eggs) came from a local 100% grass-based, biodynamic, A2 certified (raw) dairy farm that practices Calf at Foot where the calf stays with its mother, something that’s important to me. I’ve known the owner for over 16 years now. I found his farm just after my spine collapsed and I was recovering from veganism. After hearing what happened to me, he started supplementing his herd’s diet with sea minerals to give me the most nutrient dense milk possible. The man is an earth angel. We geek out on health and science whenever I get the chance to visit the farm. He introduced me to the French scientist Louis Kervran and his controversial theory of biological transmutation and last time I saw him, he had started using a refractometer to test the Brix of his herd’s milk. Thank you for the heads-up on Vital Farms. I saw a YouTube video on it a month or so ago. I had always assumed their hens were fed supplemental feed containing soy as it’s a common practice in the industry, even for pastured. I don’t know of any brand on the market whose hens are fed entirely on pasture—Angel Acres Farm, owned by the ‘Strong Sistas’, sells eggs that are tested to be low in PUFA, though—or if it’s even possible to maintain the health of the hens and egg production to meet demands, while keeping the cost of eggs reasonable enough to not offend the consumer. With that said, I haven’t bought their eggs since maybe 2024. I buy a “humanely hatched” brand that uses the technology in-ovo sexing to end the practice of chick culling. It’s great that you’re tolerating bananas better. That’s another good indication your health has improved. Did cooked bananas also cause a serotonin response, previously? If I’m not mistaken, Ray recommended cooking them because of the raw starch. I used to only tolerate them raw when overripe. I haven’t had them in quite some time, though. My diet was further simplified because I’m having to prepare 6 meals a day, currently. Thankfully, I overcame the dysautonomia so the only effect protein has on me now is positive, but the majority of my fuel came from potatoes—I was averaging upwards of 4 lb daily. The concentrated carbs helped, but it was immersing myself in nature regularly on the trail that was most responsible for calming my nervous system and restoring my thyroid function so my adrenals weren’t having to compensate with adrenaline. I had this epiphany that it was not my body that needed convincing it was safe to relax, but me who needed it. I’ve heard it said that we should get out of our comfort zone, but it occurred to me that I’ve never had one. Figuratively speaking, I’ve been putting out fires since I was a child and always preparing for the next one. I knew I needed to take my healing beyond the cell back to the self, but it was challenging to do so when I felt so disconnected from myself, hollow even, since my mum’s passing and distracting myself with the demands of caring for my dad wasn’t going to reconnect me. I didn’t overcome the dysautonomia overnight, but I stayed committed to getting out on the trail at least 4 days a week, and one day, while on the last mile stretch of one of my hikes, I had a moment, a breakthrough, when there was what I can only describe as a lifting of the veil between this world and heaven. I thought I knew peace, but just like hell has no floor, the depths of it are endless, I discovered that day that heaven has no ceiling. To go from feeling completely disconnected to feeling connected to not just myself but everything, to know life’s tragic realities, intimately, and at the same time its miraculousness, was life-affirming. I was reminded that the source that created the mountains I’ve climbed is the same source that created me to be just as enduring, and whatever comes my way I can handle it because in hindsight I always have, and where, in the past, I would have gone into fire-extinguisher mode hearing the doctor say my dad had what killed my mum, I felt at ease, in the flow and have remained so. I’m not just drifting around the ocean on a surfboard, at the mercy of the water. I am the water. And thank you. ️ Yes, you can definitely relate. Being a caregiver is a lot, but I’m just so grateful to have more time with my dad that I didn’t have with my mum.
  • Discussing pistol squats, concentric exercise, resting, and other forms of strength training.

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    C
    I thought aspirin and/or baking soda w water is good for afterwards? Gummy bears or fruit before and during lifting, no?
  • 16 Years Old & Acne Issues

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  • 3-4am waking

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    JenniferJ
    @SpaceManJim said in 3-4am waking: Odd that nobody's mentioned it, especially after seeing your username, but... How about salt? Probably because he listed salt before bed under the things he has tried.
  • extreme dopamine detoxing peaty?

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    KilgoreK
    @the-MOUSE Maybe the terminology is wrong but I think cutting out socials, music and doing what you proposed have incredible benefits. You can fix your life in a couple months if you actually try. Even if you avoid bad things before the evening you will see great results.
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    I watched the whole vid, was intrigued from the first few mins when he described a very intuitive and somewhat Peat-related approach: lots of carbs, lower stress, high agency lifestyle. He then goes into his staple meal being red meat and rice, plus unlimited fruit, which seems like a pretty solid way to run one's diet. But it also made me think about how just being active every day is such a huge factor in one's body composition. This guy, like many YT fitness influencers, don't have "real" and sedentary jobs, including stressful commutes. They just live a "more natural" life, are on their feet way more, always moving, don't have low-grade stress associated with constant use of Microsoft Office products (lol!). I've noticed this effect pretty pronounced in myself. I'm an office worker by day with side business ambitions I work on during evenings and weekends when possible, so it's a lot of 'modern day office work'. I also do intense weight training 3x a week and a few bouts of cardio via martial arts, so I'm in reasonable shape - strong with slightly visible abs and ~15% bodyfat. But when I'm not working, not having an alarm clock, for extended periods of time, my physique just takes on that extra ~25% of quality that's hard to describe - everything feels and looks tighter, more abs visible while at same body weight, energy levels and lifts are maybe 10% better automatically, etc. I tolerate any and all foods way better too. I really get the sense that if I focused on living life this way for more than a few weeks on vacation here or there, I could be making these dumb "here's my life as a fitness guy" videos lol. Just being on my feet walking some European city on vacation for a few days does incredible things compared to standard north American life, and people like Bill live closer to the former than the latter everyday. Not meant to brag, but rather to say that I believe most anyone could quickly and continuously improve their physique and physical well-being if they make appropriate trade-offs in life. And I'm sure those of us stuck in the corporate North American grind can continue to find and apply principles to improve our health and fitness too.
  • thoughts on just following elemental diet?

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    the MOUSET
    @the-MOUSE #tnd
  • demoralization / blackpoll propaganda is cringe

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    Milk DestroyerM
    @sneedful The thing is I don't think that sort of escalation is impossible but panic posting about it is not helping. Unless he is inviting us all round his place for tacos?
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  • glutamine? good or bad?

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    LucHL
    @wester130 said in glutamine? good or bad?: why is gelatin so high in glutamine? We don't use gelatin for glutamine but for collagen. Collagen is rich in glycine and proline. Glycine is going to moderate the possible excito-toxicity of glutamate (change of glutamine into glutamate (glutamic acid) in the process of assimilation, partially). Collagène composition: Protéine 86 – 92 % Glycine: +/ 30 % (+5 / -9) Proline: +/ 18 % (-6) Hydroxyproline: +/ 14% (-2 / +2) Alanine: 11 % (-2 / +1) Lysine: 5 % (-1) NB: Pour le collagène selon Ray PEAt, myprotein .com, Great lakes. Si prise de glycine : 2 x 5 g, assimilation 20 % selon un post de Haidut.
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  • high b12 from blood test

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    E
    @LucH said in What peaty substance is closest to cannabis/CBD on mental and physical relaxation?: @Ecstatic_Hamster said in What peaty substance is closest to cannabis/CBD on mental and physical relaxation?: CBD is not deleterious to neurons. Where did you get that idea. It helps inhibit excessive neuronal firing. Cannabinoids reduce brain connectivity I know several studies demonstrate beneficial effects on pain. Mercola has written a thunderous article on the benefits of medical cannabis. I remember having heard a psychiatrist (radio interview) saying we lost partial connectivity from neurons, becoming useless. But as we only use 10 % of our capacity, problems shouldn’t arise, unless teenagers begin to regularly smoke cannabinoids. Marijuana is however safer than cocaine, but with new synthetic mix drugs, it’s another problem… Excerpt The study’s findings revealed significant disruptions in brain connectivity across several key networks after cannabis administration. These networks include the executive control network (ECN), salience network, hippocampal network, and limbic striatal network. Specifically, the ECN, responsible for higher-order cognitive functions like decision-making and cognitive control, showed reduced connectivity under the influence of both THC and THC + CBD. Source: New neuroscience research: CBD does not temper THC’s effects on brain connectivity, may enhance disruption. In PsyPost, by Eric W. Dolan July 23, 2024 in Psychopharmacology Brain > Cannabis. https://www.psypost.org/new-neuroscience-research-cbd-does-not-temper-thcs-effects-on-brain-connectivity-may-enhance-disruption/ Thank you for posting this. It isn’t my experience and I don’t think this is much of a study. But I appreciate it. I never gave this one any credence. There are much better studies that show the opposite.
  • Idealabs Solvent

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    BaseBornPeaterB
    @temple-of-salt I believe the main purpose of the SFA/ ethanol mixture is that it should greatly increase topical absorption of whatever is dissolved in it. Really great for stuff like vit K where a good topical dose would end up in me cutting up several capsules and mixing them with coconut oil on my legs. The olive oil may still be preferable for topical use on more sensitive areas, or for making into diy cosmetics etc. I’m unsure if one is better than the other for oral use other than olive oil being more pleasant to squirt into your mouth.
  • Dates

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    DavidPSD
    Haidut recently wrote That corroborates Ray’s views that one should be careful when consuming foods naturally high in 5-HT such as kiwis, dates, and (unripe) bananas. http://haidut.me/?p=2700 Peatbot.com: The context provided suggests that there are concerns about the use of 5-HTP (5-hydroxytryptophan), which is a precursor to serotonin. It is mentioned that while 5-HTP might elevate mood, it could also have potential negative effects. These include an increased risk of breast cancer, obesity, and other adverse effects due to its role in raising serotonin levels. Excess serotonin is associated with increased estrogen, which can slow liver metabolism, suppress thyroid function, and potentially lead to obesity and cancer. Therefore, while 5-HTP is sometimes used as a natural supplement to boost serotonin, there are significant concerns about its long-term health effects.
  • how matt stonie competitior eater still good health idnicator?

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    the MOUSET
    @the-MOUSE you fattys keep coping. john pork is calling me i must attend
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  • Low Estrogen from Androsterone

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    G
    I have experienced the same. I started using it without any bad side effects, and I took andro on off for a couple months. After awhile worse and worse symtoms such as low libido (My sex ability was fine but my desire was near 0), anhedonia, apathy all manifested which scared me as they were strong. It took some time but eventually I correlated this to low estrogen and I went to have my levels checked and they came back as: estradiol: 95 (pmol/L) testosterone: 26 (nmol/L) free testosterone: 15(nmol/L) SHBG: 28(nmol/L) The estrogen is right in the middle of the reference range which was very strange. I did still feel all the symptoms but I hadn't taken the Andro for a couple of days before the test. Aromatase Inhibitors are quite scary, I read on Excelmale forum about something called PAMD or Post AI Major Dysfunction where symtoms are basically like PSSD from finasteride or SSRIs. https://www.excelmale.com/threads/persistent-low-e2-symptoms-lasting-long-after-crash-possible-solution-or-a-little-relief.27402/ Now a couple months after I still don't feel back to how I was but I am able to function. I didn't use much Andro but on one occasion I applied roughly 20 drops to my scrotum (it is following this that much of the negative symptoms started).
  • Pansterone

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    @temple-of-salt https://lowtoxinforum.com/threads/pansterone-liquid-pregnenolone-dhea-mix.7426/ personal thoughts: he has changed the formula a lot of times I think there is a big difference with the alcohol and oil solution It's probably his best supplement it's effective, it shouldn;t convert to estrogen but it will in sickly people
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    DavidPSD
    @cs3000 said in Erosive Arthritis (Osteoarthritis not rheumatoid), ray peats article + case report in fingers using thyroid: Thyroid + Famotadine should be effective for osteoarthritis restoration Thiamine (B1) is also a carbonic anhydrase inhibitor. It might be useful here as well. Inhibition of mammalian carbonic anhydrase isoforms I, II and VI with thiamine and thiamine-like molecules
  • When to take Cyproheptadine for sleep?

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    Milk DestroyerM
    @DkJoe2 I wonder if exogenous l-dopa would convert instead to adrenaline though? And is tyrosine use safe, it being a standalone amino-acid? I suppose it'd be a matter of individual experimentation
  • Body Temperature higher in the morning than in the evening

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    JenniferJ
    @leon-damjanov, it sounds like you run on stress hormones to compensate for poor thyroid function. Adrenaline raises temps and lowers TSH, giving the false impression that thyroid function is good. The biggest give away to me are cold extremities. Adrenaline cuts off circulation to extremities to keep vital organs warm when thyroid function is poor. The stress of darkness and fasting at night may be triggering adrenaline, causing your temp to be normal in the morning, while eating throughout the day lowers adrenaline, resulting in lower temps and revealing what your actual thyroid function is. Regarding weight, I’m thin, consume a lot of calories for my size and activity level, and have a history of running on adrenaline due to a weak thyroid. Ray Peat talked about people like us whose hypothyroidism often goes untreated because we aren’t overweight.