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Subcategories

  • Scientific papers, books, blog posts. Discussion of whatever you find interesting and notable.

    541 Topics
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    MauritioM
    Aspirin alleviates fibrosis in mouse model. Hed~600mg. https://pmc.ncbi.nlm.nih.gov/articles/PMC12226408/
  • Websites, newsletters, articles, podcasts, interviews, explainers, books, and other resources that relate to the work of Dr. Raymond Peat.

    61 Topics
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    yerragY
    @what-about-bob Thanks. I like the summary. How everything all fits in from theae great minds and put together by Ray Peat into more practical lifestyle applicable ideas. I am appreciating how I see myself on the "applied technology" end of their contributions as I incorporate these ideas into my attempt to be my own doctor as I attempt to improve my health. I have been unable for the past 24 years to lower my blood pressure without using prescription medication. But I am seeing the light at the end of this tunnel. It is a long process of learning and I don't give up. Thanks to recent developments in science and technology, I may be able to lower my blood pressure finally using ideas from Peat and his predecessors. What has been helpful is my use of AI as an efficient research assistant and aggregator of concepts and minute details that my own limited human mind can't recall easily and utilize readily.
  • Do you have a question? You can post it here, but you will only receive unqualified personal opinions and NOT medical advice in any shape or form. If something seems like medical advice but it's posted in this category, it's actually a personal opinion.

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    S
    ^^^^what he said. He’s always taking about his labs and dropping some numbers, but I’ve never seen them posted, especially not in a comprehensive fashion. Maybe they’re behind a paywall, I don’t know.
  • From medical devices to supplements. Red lights, CO2 tanks, large trash bags, kuinone, and more.

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    H
    How is it going pannacotta?
  • Recipes, food, meal prep, brands. Discuss them all here.

    226 Topics
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    H
    Behold the mighty äggost a favourite of mine. lots of eggs and milk [image: 1766841381485-aefba33a-8f81-4fd5-89dd-a2c3a41dbc2f-bild.png]
  • Discussing pistol squats, concentric exercise, resting, and other forms of strength training.

    85 Topics
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    BioEclecticB
    @jamezb46 said in pre workout / intra / post workout: @BioEclectic Why do you think lactic acid produces DOMS? From what i had read at the old RPF forum, though i always hold open the possibility that i have either misconstrued or misremembered whatever i had read. Not sure if this applies but I do know it noticeably reduces work or shoe related foot soreness. Mag sulfate and Mag bicarbonate.
  • Prevent metabolic damage in extreme caloric deficit

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    You'll want plenty of Vitamin E to protect from the fat you are releasing as you lose weight. I also love theanine after workouts. It helps to reduce serotonin and estrogen. I prefer 0.7g protein per pound of your target bodyweight. It would help to know how heavy you are now and what you plan to do to lose the weight. You should avoid steady-state cardio except as walking. I would do HIIT sessions on an exercise bike 3x/wk and lots of walking. Walking outside will do the most for you but in the gym you should walk at a steep incline on the treadmill to burn the most calories. You'll want to keep your muscle until close to you weigh-in date, but high reps will push more fluid into them without boosting their metabolic rate. Stick to 1-3 reps per set.
  • Normal body temperature is now 97.9. "it’s rarely as high as 98.6 F"

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    yerragY
    @CrumblingCookie said in Normal body temperature is now 97.9. "it’s rarely as high as 98.6 F": s it just PUFA? Is it an altered setpoint of carbohydrate/caloric malnutrition? Is it electromagnetic interference of physiological cellular functioning? Is it a (low-key) chronic disease state? PUFA is one key reason. The more PUFA and the less SFA the fat being used as a substrate in fatty acid metabolism, the more likely the mitochondria is deprived of co-factors it needs to run on sugar-based mitochondrial metabolism. Sugar metabolism becomes cytosolic and glycolytic, which produces much less energy. More lactic acid is produced and less CO2. Less energy already makes for lower temperature. But it gets worse when the body has less available CO2. Because enough CO2.is needed in the blood to effect adequate tissue oxygenation of our cells and tissues. Without enough oxygen in the tissues, the body will keep on producing energy inefficiently by producing energy from sugar glycolytically, and become more dependent on fatty acid mitochondrial metabolism, the mitochondrial pathway throttled as it is on oxygen being limited already. The combined capacity of the mitochondria and the cytoplasm to produce energy will be much less, and this would be reflected in lower temperatures across the board. Last year my lungs had bronchitis and I was not getting enough oxygen from breathing. At that state, and unaware of the effect of has, I dove in my fishpond to clear some debris from the bottom. I got hypothermia from it. I was shivering a lot, and struggled to come up. My temperature has gone down to 35C in less than a minute.
  • Raymond on L-Theanine

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    CearrsonC
    @LucH Great stuff thank you.
  • DNP in ethanol

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    M
    @grymsky90210 Lol thanks. I have lost some weight. Not sure it's because of the DNP tho. I have dosed it very sporadically. Mostly just used it on cold nights to stay warm but not even sure I have even felt those effects much. I thought ethanol would enhance it's effects but hasn't been the case for me. But this was by no means a perfect experiment. Did not take it regularly and am very likely underdosing.
  • Progest-E as a contraceptive.

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    SunnivaS
    It would be vaginally. I think the idea is that while pregnant, the body ramps up progesterone to support pregnancy. Using vaginally is to make the body think it is already pregnant, and therefore would not have need for another implantation. Ray Peat spoke about this in an interview.
  • Topical Vitamin K2 for regrowth

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    T
    @onliest thnaks, never heard of this, but then again I'm in Europe...I will have to mix it myself since they don't ship overseas.
  • What to do about Orange Juice causing high histamine?

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    LucHL
    @sneedful said in What to do about Orange Juice causing high histamine?: dates dont have high oxalates, the exact info is available from studies. I have several sources mentioning no oxalates and other "respectful" ones (4x) mentioning the contrary. I can post if you're receptive And why : Oxalates are natural compounds found in vegetables, fruits, nuts, and grains. This inhibiting effect is due to the binding functions of antinutrients in plants in order to protect the species: If the animals eat too much of them, the natural cycle would be stopped.
  • Vitamin E safe for daily consumption?

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    DavidPSD
    Peatbot: Yes, vitamin E has undergone significant changes over the years. Originally, vitamin E was produced using methods that resulted in a product that was thick, viscous, and often brown in color. This form of vitamin E was associated with beneficial effects, including anti-estrogenic and anti-clotting properties, and was thought to protect against the toxic effects of polyunsaturated fatty acids (PUFAs). However, over time, the manufacturing processes for vitamin E have changed. For example, when ADM bought the old Eastman distillation products factory, they altered the methods of production, which affected the consistency and appearance of vitamin E. The newer vitamin E products became more diluted, often with soybean oil, which is highly unsaturated. This change in formulation has been linked to a reduction in the beneficial effects that were observed with the original vitamin E products. Additionally, the perception and definition of vitamin E's role have evolved. Initially, it was recognized for its fertility-enhancing and anti-estrogenic properties, but later it was primarily marketed as an antioxidant. The changes in manufacturing and formulation have led to variations in the effectiveness and safety of vitamin E supplements, with some studies suggesting increased mortality associated with certain formulations. Overall, the form and quality of vitamin E have shifted, and these changes have influenced its perceived health benefits and risks. Peatbot: Yes, vitamin E is generally considered safe to take on a daily basis, especially when taken in appropriate amounts. The context suggests that about 30 to 50 milligrams per day can provide full protection. However, it's important to choose a high-quality vitamin E supplement, preferably one that contains mixed tocopherols, as these are anti-inflammatory. It's also noted that vitamin E is particularly beneficial if you are consuming polyunsaturated fatty acids (PUFAs), as it can help counteract some of their negative effects.
  • This topic is deleted!

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  • Is tyronene from idealabs(taken orally) just as effective as cynomel?

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    serotoninskepticS
    @LetTheRedeemed Yea ray also said that thyroid is unstable dissolved in alcohol I believe
  • What is your favourite substance/ supplement for reducing cortisol?

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    L
    @Jennifer said in What is your favourite substance/ supplement for reducing cortisol?: Ice cream. based
  • Does anyone here use greek unipharma t3?

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  • T3 hell yeah

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    ?
    @Kvirion underground steroid sites almost always sell T3 since it's popular in their sphere Unipharma is from greece and actually pharmagrade,you have to search for a trusted brand
  • Best country/location to live in

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    ?
    @White Do you have no friends? No family? Remote income? In that case, you ought to travel and see for yourself the corners of the world. See what appeals to you with your own eyes. Then consider whether to settle down there and set down roots.
  • whats your opinion on taking kefir?

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    yerragY
    @RawGoatMilk88 That one is good. Mike Fave recommended that to me as well.
  • Share positive experiences with eating liver

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    serotoninskepticS
    @yerrag Haha thats a funny dtory I hope its true
  • T3 vs Aspirin (for fatigue)

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    serotoninskepticS
    @James T3 works better for fatigue in my experience. Aspirin doesnt have notable effects on my energy
  • 0 Votes
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    serotoninskepticS
    @the-MOUSE Lundberg's Basmati White Rice tests the lowest in arsenic. White rice is your best bet for grains
  • How should serotonin depletion feel like?

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    D
    Also I remember reading something about how tyrosine is converted to dopamine (which will drop serotonin) when sunlight is directed at the scalp so get some sun to improve your results.
  • Milk fat

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    J
    @RawGoatMilk88 In what way is skim milk nutritionally devoid? It doesn't contain much in terms of fat soluble vitamins but it still has plenty of b12, b2, calcium, ect and is a good protein source