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Subcategories

  • Scientific papers, books, blog posts. Discussion of whatever you find interesting and notable.

    626 Topics
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    U
    Increased Androgens: A pilot study on male volunteers (1 g/day for 1 month) found that DCI administration was associated with a +23.4% increase in testosterone and a +13.8% increase in dehydroepiandrosterone (DHEA). Reduced Estrogens: In the same study, DCI significantly reduced estrone levels (-85.0%) and reduced estradiol levels (-14.4%). Androgen Precursors: In addition to DHEA, other androgen precursors like epiandrosterone also increased (+39%). Aromatase Inhibition: DCI is believed to act as an aromatase down-modulator (inhibitor), reducing the conversion of androgens (like testosterone) into estrogens (like estradiol and estrone). D-chiro-inositol (DCI) acts to stimulate PDHP (pyruvate dehydrogenase phosphatase), which in turn dephosphorylates and activates PDH (pyruvate dehydrogenase). Insulin Mimicry: DCI has been shown to reduce the concentration of required for full activation of PDHP, a mechanism similar to how insulin works in adipocytes
  • Websites, newsletters, articles, podcasts, interviews, explainers, books, and other resources that relate to the work of Dr. Raymond Peat.

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    C
    Cancer Treatments – from Research to Application MCS Foundations for Life, In memory of my dear wife Mihaela Catalina Stanciu https://www.cancertreatmentsresearch.com/ https://jeffreydachmd.com/cancer-articles/
  • Do you have a question? You can post it here, but you will only receive unqualified personal opinions and NOT medical advice in any shape or form. If something seems like medical advice but it's posted in this category, it's actually a personal opinion.

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    LucHL
    @engineer said in Too high systolic blood pressure?: Should I keep using them or or lay them off? I'd stop the whole thing for 3 days. To avoid interference with half-life molecule and a return to +/ balance. Then I'll see the the interconnection of the molecules and the lack of. If you stress, you lack magnesium bisglycinate. There is interaction between B1 B2 B3 B6 + B8iotine. No more than 20-25 B3 if niacin (histamine flush). Here no caffeine until it's fine. wait 5 days. Need carbs (glucose & fructose with fiber) when taking caffeine again. Half life is 5-6 hours for caffeine. Too much caf interfere with adenosine and serotonin afterwards. And don't take a high dose because you've already done it before and everything was alright... Need l-theanine if you're angry / disturbed / in bad temper ... + a relax technique (breath) for 3'.
  • From medical devices to supplements. Red lights, CO2 tanks, large trash bags, kuinone, and more.

    383 Topics
    4k Posts
    loessL
    Wow, glad you're feeling a lot better. I think I might actually be experiencing something similar and I hadn't even considered it. I packed away my UV lamp in January in preparation for a move, and shortly after that started supplementing daily 5000 IU of vitamin D in olive oil because I had gotten lab results that came back low for 25-OH vitamin D @ 30 ng/mL. It's the larksupply.co vitamin D, which is pretty much unparalleled as far as quality. I think I just simply don't tolerate oral vitamin D for whatever reason. Since I got to my new place at the beginning of February I haven't been myself at all. My sleep has been inconsistent, full of interruptions for no reason, and waking up has felt like being a vampire glued to the inside of a dark coffin. I've been super lethargic, and I'd also describe my mood and perceptual capacity as both stupid and irritable. Have also been hit with random nonsensical bouts of anxiety and fear that are way out of my norm. I've been so out of wack and dragging that I haven't bothered to get that lamp out and set it up since I got here. I thought it was remnants of the flu that knocked me down a week before I moved, but I think it is very possible that the vit D supplementation might actually be responsible for seriously messing me up since I arrived here. Cutting it out and going back to the lamp.
  • Recipes, food, meal prep, brands. Discuss them all here.

    233 Topics
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    LukeL
    You can try to find a good Thai Curry paste without bad ingredients like seed oils. They are available with red, yellow or green color. Sauté some vegetables in a pot (Onions, carrots, zucchini, peppers, whatever you like - if you use broccoli, better cook it in water before, otherwise it will be half raw). Add meat, white fish or shrimps. Add the curry paste and mix everything. Add coconut milk and let it simmer for five minuted or so. Serve with rice.
  • Discussing pistol squats, concentric exercise, resting, and other forms of strength training.

    85 Topics
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    alfredoolivasA
    @sunsunsun https://www.youtube.com/watch?v=7f25pFhuAaY
  • 100 000 - 300 000iu Vitamin D per day - CURES MS

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  • Cyprohepaptidine Vs Minocycline

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    hwisdomH
    @hwisdom and yes I have indeed tried the carrot sallad, I ended up having to pour half a litre of vinegar and wait for 3 hrs because I clogged the toilet so hard that day
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  • serotonin inhibitors?

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    @raypneat Is aspirin? If so, aspirin.
  • Amoxicillin (Augmentin) gave me a diarrhea and possibly IBD flare up

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    Ray said positive things about lidocaine for bleeding colitis. You might research on that for a bit. @laoa Hi, yes thank you, I'm aware of lidocaine, but the sources i've found so far feel a bit sketchy (if you have a trusted source, please share), so I think I'll try other options first. I've seen people have success with niacin, apple pectin, and xylitol (all of these should mainly work by increasing butyrate production in the gut). Also, acute gastrointestinal problems and fever could also be an allergic reaction to augmentin. Yes, but I think "allergy" is just an umbrella term for the things mainstream medicine is clueless about. Like in this case it could be that my intestinal permeability was already really bad in the first place and the Augmentin killing the bacteria in the gut and them releasing their endotoxin was the final straw, or something along those lines
  • How to handle blood sugar spikes at 17

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  • Cancer cells actually have high NAD/NADH ratio

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  • cancer

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    E
    @gg12 fat, sugar, glutamine.
  • A bunch of random studies #1

    coconut oil tendon nicotinamide depression sleep
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  • Where do I start 17m

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    gg12G
    @LucH ah good to know thanks for some examples
  • food and supplements

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    @Jakeandpace Thanks for this bit of info. Essentially, that's marking out the importance of feeding sufficient nutrients and cofactors to the otherwise starving nerve cells, which are particularly strongly energy-dependent, as they become more active and craving for substrates when boosted by PLP. So it offers an explanation for adverse effects of PLP, pointing specifically to CoA and therefore vitamin B5. Which is useful. However, what remains completely untouched by this are all those adverse effects from supplementing pyridoxine which are not mediated through PLP but caused through PN, PM, PL, i.e. the adverse effects which distinguish supplementation of PLP from supplementation of PN.
  • 16 Years Old & Acne Issues

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  • 3-4am waking

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    JenniferJ
    @SpaceManJim said in 3-4am waking: Odd that nobody's mentioned it, especially after seeing your username, but... How about salt? Probably because he listed salt before bed under the things he has tried.
  • extreme dopamine detoxing peaty?

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    KilgoreK
    @the-MOUSE Maybe the terminology is wrong but I think cutting out socials, music and doing what you proposed have incredible benefits. You can fix your life in a couple months if you actually try. Even if you avoid bad things before the evening you will see great results.
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    I watched the whole vid, was intrigued from the first few mins when he described a very intuitive and somewhat Peat-related approach: lots of carbs, lower stress, high agency lifestyle. He then goes into his staple meal being red meat and rice, plus unlimited fruit, which seems like a pretty solid way to run one's diet. But it also made me think about how just being active every day is such a huge factor in one's body composition. This guy, like many YT fitness influencers, don't have "real" and sedentary jobs, including stressful commutes. They just live a "more natural" life, are on their feet way more, always moving, don't have low-grade stress associated with constant use of Microsoft Office products (lol!). I've noticed this effect pretty pronounced in myself. I'm an office worker by day with side business ambitions I work on during evenings and weekends when possible, so it's a lot of 'modern day office work'. I also do intense weight training 3x a week and a few bouts of cardio via martial arts, so I'm in reasonable shape - strong with slightly visible abs and ~15% bodyfat. But when I'm not working, not having an alarm clock, for extended periods of time, my physique just takes on that extra ~25% of quality that's hard to describe - everything feels and looks tighter, more abs visible while at same body weight, energy levels and lifts are maybe 10% better automatically, etc. I tolerate any and all foods way better too. I really get the sense that if I focused on living life this way for more than a few weeks on vacation here or there, I could be making these dumb "here's my life as a fitness guy" videos lol. Just being on my feet walking some European city on vacation for a few days does incredible things compared to standard north American life, and people like Bill live closer to the former than the latter everyday. Not meant to brag, but rather to say that I believe most anyone could quickly and continuously improve their physique and physical well-being if they make appropriate trade-offs in life. And I'm sure those of us stuck in the corporate North American grind can continue to find and apply principles to improve our health and fitness too.
  • thoughts on just following elemental diet?

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    the MOUSET
    @the-MOUSE #tnd
  • demoralization / blackpoll propaganda is cringe

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    Milk DestroyerM
    @sneedful The thing is I don't think that sort of escalation is impossible but panic posting about it is not helping. Unless he is inviting us all round his place for tacos?
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  • glutamine? good or bad?

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    LucHL
    @wester130 said in glutamine? good or bad?: why is gelatin so high in glutamine? We don't use gelatin for glutamine but for collagen. Collagen is rich in glycine and proline. Glycine is going to moderate the possible excito-toxicity of glutamate (change of glutamine into glutamate (glutamic acid) in the process of assimilation, partially). Collagène composition: Protéine 86 – 92 % Glycine: +/ 30 % (+5 / -9) Proline: +/ 18 % (-6) Hydroxyproline: +/ 14% (-2 / +2) Alanine: 11 % (-2 / +1) Lysine: 5 % (-1) NB: Pour le collagène selon Ray PEAt, myprotein .com, Great lakes. Si prise de glycine : 2 x 5 g, assimilation 20 % selon un post de Haidut.
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