Subcategories

• Literature Review

  Scientific papers, books, blog posts. Discussion of whatever you find interesting and notable.

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  @Mauritio said:

  Do you not get weird rancid butter smell from the butyrate

  Not at all. I had also used the butyrate suspended in water on my arms before and it was fine. Smell-wise it only slightly lingers when blended into oils. Maybe others with a selectively different sense of smell would disagree. Disappointing that you've given up on the topical butyrate as I would have liked to read more from your experience with it.

  I get a great cosmetic effect still. It's like a hair gel /wax strengthener .

  Could it be that we are referring to the same observation? The kind of coating or dry, non-sticky look of greasiness I mean could also be described as a fashionable surfer-style to out-of-bed-look. I agree the hair feels and looks smooth and nice immediately after application, easy to comb and accentuate and antistatic, i.e non-frizzy.

  I also feel like my scalp is more flexible and I can wiggle it around more easily.
  Not sure if it decreased hair loss in general.

  Generally I've noticed much less hair loss since applying this blend. It's almost as much as before on some days, though, annoyingly.

  I'm definitely liking the lactic acid. The scalp seems smoother and less dry after regular use. I've looked through reviews online of pure LA drops and many people use it to rub their faces with, reporting smoother and fuller skin.

  Intuitively I'd still like an alternative to the ethanol as a preservative and feel there's more immediate leeway for improving the scalp skin barrier and therefore the endogenous nutrient homeostasis. I don't want to obtain and store every possible substance but still perhaps blend in either something like those apple polyphenols or flavonoids like apigenin as a complementary (and definitely non-smelly) HDACi.

  Another thought is, that if there's a reason to (always or specifically) suspect aforementioned inflammatory fungal influences I should really trial adding that pirocton olamine. Especially since the extra topical glucose would feed them too (and first).

  @Gardner said:

  So many ingredients . How are you going to pinpoint what exactly helps if anything helps?

  The bottom list is still ideas to look through by me, or by you, or by any reader. Essentially, I'm currently only applying dextrose, LA, butyrate, KCl.

• Ray Peat Resources

  Websites, newsletters, articles, podcasts, interviews, explainers, books, and other resources that relate to the work of Dr. Raymond Peat.

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  @DKJoeAgain so does this mean that losing body fat may in "his" theory increase intelligence?

• Not Medical Advice

  Do you have a question? You can post it here, but you will only receive unqualified personal opinions and NOT medical advice in any shape or form. If something seems like medical advice but it's posted in this category, it's actually a personal opinion.

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  @LucH I forgot to mention, the protein and calcium is mostly from skim milk, which is why both values may seem high, my diet is essentially 2-3L of skim milk and some low fat yogurt from morning on, and dinner is a regular balanced meal with most of the fats being at dinner.

• Products

  From medical devices to supplements. Red lights, CO2 tanks, large trash bags, kuinone, and more.

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  @samson Why would you need more dietary cholesterol? If anything supplementing with an end-point androgen would initiate feedback loops leading to less steroidogenesis, thus lowering the dietary requirement for cholesterol, right?

  Or maybe you're referring to the fact that androsterone is a thyroid mimetic, thus increasing metabolism in steroid-producing organs, thus leading to a higher requirement of dietary cholesterol?

  Perhaps you would need more cholesterol because androsterone or its metabolites, being 5AR androgens, stimulate their own synthesis, thus increasing the need for dietary cholesterol to fuel the enhanced steroidogenesis?

  I don't know which possibility is correct, but if you know which is correct, please enlighten us.

• The Kitchen

  Recipes, food, meal prep, brands. Discuss them all here.

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  From another reddit thread on mushroom supplements and coffee:

  All Cordyceps bioactives are water-solubles. Never combine Cordyceps with coffee or milk.

  Coffee w/caffeine is an adenosine antagonist. Adenosine is one of the main quality markers of Cordyceps. The other is cordycepin, a related adenosine derivative. Cordycepin i.p. is responsible for the energising effects of Cordyceps: it's responsible for the vasodilating and testosterone-inducing properties.

  Milk contains lactose. Lactose binds to polyphenols, rendering them useless. Polyphenols are mainly antioxidants, also present in Cordyceps. They have their own benefits.

  Skeptical of this post because the posters says "coffee with caffeine is an adenosine antagonist."

  From AI:

  Other Notable Effects

  Adenosine levels increase in response to cellular stress, acting as a protective signal to limit tissue damage.

  Caffeine and related compounds act as antagonists to adenosine receptors, which is why caffeine promotes wakefulness by blocking adenosine’s sleep-promoting effects.

  It seems like the argument is that coffee + cordyceps basically means you're nullifying cordyceps because caffeine blocks some of its main structure. In other words just paying for expensive coffee.

• The Gym

  Discussing pistol squats, concentric exercise, resting, and other forms of strength training.

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  @BroJonas @raytreats yup this guy is great. keeping a stack and doing incline presses and chest dips is the way to get big pecks fs.