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  • Scientific papers, books, blog posts. Discussion of whatever you find interesting and notable.

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    LucHL
    More info on the way how coco acts... How does coconut oil can stabilize or protect ingested PUFA from oxidation? Key ideas Coconut oil is not just resistant to oxidation but it can stabilize membranes. Coconut oil protects against the inflammation caused by endotoxins (but don’t use coco in case of a detox at the beginning of the process because it could amplify the immune reaction). SFA has an impact on enzyme expression when use in high amount (far from the ratio 2:2:1 for SFA/MUFA/PUFA). If you have a high intake of LA (omega-6), it can compete with ALA (omega-3) for the enzymes that are responsible for converting ALA into anti-inflammatory eicosanoids. SFAs like lauric acid (from coconut oil) don’t require desaturases. Thus, adding coconut oil won’t inhibit PUFA processing by competing for those enzymes, because SFAs don’t undergo desaturation. Coconut oil is 90 % SFA with 2/3 MCT oil. Adding coconut oil may help protect membranes by giving a spatial and stabilizing protection, improving membrane packing. ! Caveat: Balance is Key: Too much of a good thing is bad. How does coconut oil can stabilize or protect ingested PUFA from oxidation? Coconut’s structure, primarily consisting of saturated fats, is less susceptible to the chemical reactions that cause oxidation. Not just opposing resistance or fragility to oxidation (rancidity) but the way SFA can stabilize membranes. Coconut oil can indirectly protect PUFAs from oxidation by stabilizing the overall lipid environment and potentially influencing PUFA metabolism. (1) Saturated fat content, particularly medium-chain fatty acids (MCFAs) like lauric acid, can help to pack and stabilize cell membranes, making them less susceptible to the damaging effects of oxidation. Additionally, coconut oil's unique fatty acid profile and natural antioxidants may further contribute to its resistance to oxidative damage. When adding SCFA in a meal having some PUFA, it forms a tighter packing; when incorporated to tissues, it reduces the space available for PUFA chains to move and react with free radicals, thus stabilizing the membrane and protecting PUFAs from oxidation. Ray Peat, making a extrapolation in “Unsaturated fatty acids: Nutritionally essential, or toxic?” Question to AI How can SFA from coconut oil stabilize and thus protect incorporated fat in membrane? A clue: When incorporated to tissues, it reduces the space available for PUFA chains to move and react with free radicals, thus stabilizing the membrane and protecting PUFAs from amplifying ROS. Detailed answer on the link. https://mirzoune-ciboulette.forumactif.org/t2109-english-corner-coconut-oil-stabilizes-or-protects-ingested-pufa-from-oxidation#30204
  • Websites, newsletters, articles, podcasts, interviews, explainers, books, and other resources that relate to the work of Dr. Raymond Peat.

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    CiceroC
    I noticed the reprint of Nutrition for Women says "100 short articles by Ray Peat, PHD," where the old one said "92...". What did they add to it? Also, note that From PMS to Menopause is for sale on Peat's website but not Amazon, and Peat's website doesn't have Generative Energy. Weird. I wonder if Katherine gets more of the money if you order from Peat's site. I'd imagine so.
  • Do you have a question? You can post it here, but you will only receive unqualified personal opinions and NOT medical advice in any shape or form. If something seems like medical advice but it's posted in this category, it's actually a personal opinion.

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    alfredoolivasA
    I call this Illuminatione, not dropspirenone [image: 1776734580390-96ac4c93-20b6-4a3c-b8a1-542411766669-image.png]
  • From medical devices to supplements. Red lights, CO2 tanks, large trash bags, kuinone, and more.

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    engineerE
    The connection between dopamine and serotonin https://haidut.me/?p=2830 It just so happens that dopamine and serotonin have an inverse relationship. Each one suppressed the levels of the other. Thus, when serotonin is high dopamine is low and vice versa. That relationship extends to synthetic molecules that mimic the effects of serotonin or dopamine at the receptor level. For example serotonin agonists suppress dopamine synthesis and vice versa. Serotonin (5-HT) promotes blood vessel thickening, may cause cardiovascular disease (CVD) Serotonin (5-HT) may drive brain/liver/pancreatic and many other cancers, at the genomic level Serotonin (5-HT) increases inflammatory mediators (IL-6, NF-kB), may cause atherosclerosis SSRI drugs, serotonin (5-HT) can cause chronic fatigue syndrome (CFS) Blocking serotonin may treat obsessive-compulsive disorder (OCD) Drop in dopamine behind giving up And it goes on and on and on! https://haidut.me/?s=serotonin Looks like maybe microdosing a DA could be the way to go? Edit: Looks like the weird side effects from DAs are truly just a stress response? https://lowtoxinforum.com/threads/dopaminergic-drugs-like-bromocriptine-may-treat-alcoholilsm.11828/
  • Recipes, food, meal prep, brands. Discuss them all here.

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    JenniferJ
    @Mossy, thank you for understanding. I’ve been taking advantage of the beautiful weather we’ve been having here and helping my dad build up the endurance he lost since having the flu in January so I’ve been away from my computer and the forum more, lately. I think the thread’s title should read Cooking With Mossy because you’re far more ambitious and precise with your cooking than I am. You remind me of my brother. While I hardly ever measure ingredients and prefer using my senses—for example, I can tell by smell when something is done baking—my brother is methodical and likes following detailed instructions. I joke that it’s because he’s a Virgo, a sign known for its meticulous attention to detail, sometimes to its own detriment, and that if you want something done to perfection, hire a person with Virgo (or Capricorn) placements. I’m so glad you’ve made strides with your health and with your level of dedication, I have no doubt that you’ll continue to. I think my success with thyroid is a reflection of my long-standing deficiency, having had an under-active thyroid since birth and certain stressful experiences like molestation that suppressed it further. I think the average person with a healthier history could improve their thyroid function with diet and lifestyle changes alone. Having overcome the trauma, my need to supplement is minimal now outside of winter so I’m hopeful it will eventually be unnecessary. I’ve been a swimmer since I was in utero —in fact, one of my earliest memories is me as a baby in our pool wishing my mum had put me in the blue floaty she put my cousin in, instead of the red floaty I was in because even barely out of the womb I had strong preferences and don’t care for red lol—so I don’t actually fear I would drown, but I can see myself getting tossed around like a beach ball. However, it’s not mastering surfing that I’m after, but the surfer’s relaxed lifestyle and mindset. I could easily spend hours floating in the ocean on a surfboard (or steamer trunk—shout-out to Joe ), never catching a wave, and be in total bliss if I was in the flow, just being water, my friend. Haha! Fair enough. My dad isn’t a finger tapper, though. I sometimes wish he was because it has been a struggle getting him to eat, especially since his cancer treatments. I used to make all his meals in bulk on Mondays and he would just pull whatever he wanted out of the freezer and reheat it in the microwave throughout the week, but I’m having to make him all his meals daily now because he won’t eat otherwise. LOL at ask Jennifer. I’ve been collecting random knowledge in preparation for if I’m ever a contestant on a game show. I’m convinced with each fact I gather that no matter how useless, it will be the answer to the question that stands between me and the grand prize so it goes in the memory bank. Even if there is credibility to the claimed benefits of sprouting and fermenting, it sounds like grains are only a fraction of your diet so I personally would stick with the flour that’s been working for you. You’re already eliminating the worst offenders (IMO)—the franken ingredients—by baking from scratch. The only reason I like sprouted flour is because I find it sweeter and as a devout Wonka follower, the sweeter the better. My dad doesn’t eat a ton of grains, anyway.
  • Discussing pistol squats, concentric exercise, resting, and other forms of strength training.

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    KilgoreK
    @sunsunsun said in Height Growth That Makes Sense: sports female player and take her home. Obviously a joke @sunsunsun said in Height Growth That Makes Sense: you not the guy who bragged about abusing a muslim woman in public? thats definitely not me probably the Hitler guy @epstein who I have banned btw
  • Bifidobacterium

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    alex155A
    I also plan to add Lactobacillus Reuteri to the yogurt and see what happens https://pubmed.ncbi.nlm.nih.gov/38487926/
  • Thoughts on this light nootropic stack?

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    sunsunsunS
    too much cholinergic stuff can cause an awful depression/nausea after enough time on it.
  • megadosing different magnesium supplements

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    @Wabi-sabi said in megadosing different magnesium supplements: Quinoa, Buckwheat, Amaranth, or even W What about it?
  • On The Back of a Tiger

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    R
    @Mulloch94 identity politics is dumb. Correct, identity politics is objectively rightist. The Marxian class theory is junk. Ultraleftism is bad. Xi Jinping called the class struggle of the late Mao period a "leftist mistake". The class structure of a society is a powerful explanatory factor in its functioning, though. India is worse off than China, despite starting in a similar place in the 1980s, because of the caste system's retardation of development. The typical "indian factory" video online consists of almost early-industrial constructions from the 1800s. Similar story for UK vs USA. Or Nazi Germany vs USSR. Less class tension means more coherence, productivity, war-fighting prowess. Which is why the US will lose to China in the next few decades, BTW, unless something incredible happens internally (it won't, though, until the bitter end) The same social networks that enabled Capitalism to rise are the same ones that allow Communism to function. Yep. And when those networks fail, you get a breakdown in the system (which we have seen). Sure. Requiring the establishment of new networks, and re-definition of the existing ones. This is the revolution and the historical-materialist development, et c.
  • Defanging your computer

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    I
    @Androsclerozat I think it's the screen itself - can't be good to look INTO light for hours.
  • Are beards ACTUALLY genetic?

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    ThinPickingT
    https://www.nature.com/articles/2261278b0.pdf Read sleepless harvest in the top left.
  • Fiber n coffee

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    alex155A
    @samson I'm going to restore aromatase and 5α-reductase naturally by removing blockers. and the beer was just for testing, glyphosate is not used in my country
  • Grant's rapid aging

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    GreekDemiGodG
    @sabupa I believe it's too much sunlight without or with minimal protection, He lives in Costa Rica. Daytime exposure should not be super high.
  • Good Ray peat based anabolic stack?

    ray peat steroids testosterone anabolism
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    LukeL
    Still think it's a troll account. Taking isotretinoin proactively because testosterone could give him acne... not even 14 year old me could have come up with that.
  • What causes the pattern? (Male Pattern Baldness Explained)

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    H
    I've seen some pretty crazy results with head massage on Perfect Hair Health website, I dunno. It definitely works, but the results pairing it with other things are usually better.
  • High Metabolism Weight Loss

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    C
    @torobravo Not really. High carb makes me hungry and I haven't seen much results with low fat milk or low fat in general. Lots of sunlight seems to help but between cold climate and chemtrails it's rare. There was a time I dropped a decent amount, I was eating yogurt and fruit daily. But that basically ended by winter which is >7 months where I'm at. My theory is lots of pufa early in life, stress, emf radiation are keeping things stagnant. I don't lift or run but have a lot of walking / physical work. I'm almost certain sugar is being stored as fat.
  • This topic is deleted!

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  • Best Soccer player in history was hypothyroid

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    lobotomizeL
    @NoeticJuice https://docs.google.com/document/d/1IeGVVmKpwlMhCijIAzZ6gHdrjFVpWdzSaloXhuEaO_I/edit?usp=sharing check this out
  • Good stack? RP based

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  • Starch and Dairy problems

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    LucHL
    @yeyo12 said in Starch and Dairy problems: What the hell am I supposed to eat lol For breakfast I often eat 2 fruits and a protein (ham or 1 slice Gouda cheese). No acid in the winter period. Take one tsp coconut oil. If you need more calories, double the portions. For midday meal, begin with a soup or a salad. Soup in a thermos if you work outside. The salad has been prepared the day before. Vary the type. I take one slice or two of the preceding evening cooked meat. If you want more calories, Greek yoghurt (150 g / 6 oz.) with a banana (ripe to avoid starch) or grape + honey or coconut sugar or muscovado. I target 50 g sugar (400 Kg) with a balance between glucose and fructose. White cheese (full fat) is an option too, in order to avoid an excess of one type intestinal bacterium. Variety is a key element if you don't want to suffer from bacterial overgrowth of one kind. If still hungry, you eat one slice of home made bread or 2 slices of Wasa: two slices of wholemeal Wasa (wheat rusk with sesame seeds). With butter and jam or apple and pear syrup. Adapt to what you like and / or tolerate. But vary ! One or two fruit for a snack. + tea or coffee with a biscuit. You can also prepare a shake with useful nutrients to balance acid-base minerals (Mg K Ca + other required nutrients). For the evening meal: Alternate rice, pasta (spaghetti /simple noodles) , frozen vegetables prepared in a wok + chicken breast or roast duck or whatever you like, but vary... NB: I use hazelnut milk instead of cow milk. No rice nor almond milk (glycemia) when I eat oat: Jordan simply crunchy (oat) (or the natural kind (simple oatmeal) + 1 tsp honey), 6 half pecan nuts, 1 tbsp raisin, shredded coconut + 240 ml hazelnut milk. You can add a half apple or other seasonal red fruits (strawberries or blueberries) Adapt to your tolerance and target (for PUFA).
  • DMSO

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  • TSH and Alkaline phosphatase

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    alex155A
    @16charactersitis Bro, I have familial hypercholesterolemia and 3 heart attacks... I don't know if it's safe to take thyroid hormones in this condition? (the last heart attack was in August 2024) I'm 35 years old, all the veins on my arms and legs hurt from K2 (pulling sensation) I take D3 every other day 2000, it's summer now, I'll try to stay in the sun longer
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    @cs3000 all “insoluble fiber” including pectin seems to be problematic. Have you seen this: https://lowtoxinforum.com/threads/soluble-fiber-causes-liver-cancer-insoluble-and-antibiotics-prevent-stop-it.26165/ ?
  • starting T3

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    LucHL
    @16charactersitis said in starting T3: I think ray alluded to the likelihood that most have too much Iodine if I understood correctly RP has suffered from an immune reaction (acne). So he had a pre-conceived feeling. And what is found on internet is an interview by Rita Lee. She gets the information out of him (she drags it out of RP). She puts the questions and gives the answers (rhetorical questions). RP has never explained clearly why, except repeating the mainstream idea, still not developing the reason.
  • who here is satisfied and reaching goals and is happy?

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    R
    I think Peating changed for me from a method of "feeling OK" (vs. feeling straight up bad often) to a method of feeling great when I started including weekly beef liver slices. idealistic Read V. I. Lenin's "Materialism and Empirio-Criticism". Or just watch the Cockshott video on the same: https://www.youtube.com/watch?v=D-VQkT8TcJM Ray Peat Said: One of Lenin's best pieces of writing was explaining essentially that the concept of materialism in the West is pure idealism, absolutely the negation of materialism in Lenin's sense. Lenin said knowledge is composed of memory, but the memories are recordings of experience, and experience is always new. The source of experience is matter, and so matter is only what is potential to be experienced. So materialism means looking to the future and the possibilities of experience, where the genetics and reductionists try to base their rationalism on an organization of existing knowledge, pre-existing ideas, and breaking those down into logical, computable units and so on. The essence of Lenin's type of materialism is essentially identifying it with the life process, the process of being conscious and having new experience is the process of interacting with the material world. So this is the same idea as Aristotle's prima matter, the pure potential out of which everything arises. Yep, creative potential.