@edouard

Yea I’ve tried the androgenification one and also didn’t notice anything, but I definetly have from the isolated T3

@Mauritio yea and a decent amount an hour or so before sleep could be good for sleeping through the night if wake up too soon. as would spare the glycogen for longer . i just got some coconut milk powder

there's 2 types of palm oil , that kernel oil which has a bunch of lauric acid / very different profile to the other palm oil with no MCTs or lauric acid. so probably used the 2nd type https://www.researchgate.net/figure/Fatty-acid-composition-of-palm-oil-and-palm-kernel-oil_tbl1_282129563

@ThinPicking
Ha, good catch, this one got me. Will be more on the lookout from now on.

@Mallard6146 said in Bottom Range Vitamin D:

The range is 30 - 100.

minimum target: 35 ng/ml. Optimal above 45 ng/ml, for me. But everybody won't agree 😉

Excess magnesium can hinder the absorption of vitamin D. Neither too little nor too much magnesium (RDA Mg: 360 and 420 mg according to sex f / m) is favorable. If the ratio PUFA : MUFA > 1, you will have difficulty increasing the levels of 25(OH)D. This brings us directly to 18-20g and 12-15g of PUFA consumed daily by American men and women (Kris-Etheton, 2000) and their negative impact on the absorption of already low quantities of vitamin D in food. So beware of manufactured foods which often contain an addition of soy and corn oil.
By the way, if your sun shadow exceeds your height, you will not make vitamin D. Question of wavelength.

Useful link (in French, translator needed, but with links in English):
Absorption de la vitamine D insuffisante ?
http://mirzoune-ciboulette.forumactif.org/t1664-absorption-de-la-vitamine-d-insuffisante#20619
Facteurs qui facilitent ou contrecarrent l’absorption de la vitamine D3

@raytreats

I believe Ray has said that once we stop growing, our metabolism starts to decline. The growth process uses a lot of energy in building structure.

This internal metabolism declines and if we continue the same lifestyle as we had as growing kids/adults, we won't be burning as much energy internally and we would have to start exercising more to burn that energy, or else it turns into potential energy in the form of fats.

But not everyone becomes fat. Those who don't already live a lifestyle where they have optimal mitochondrial oxidation. Their internal machinery continues to burn sugar well and the sugar does not accumulate and turn into fats by the liver. Their blood sugar is normal and stable between meals. Because they produce a lot of CO2 as well, they tend to metabolize sugar efficiently because their tissues are well oxygenated because of the Bohr effect of CO2 in blood, which allows oxygen to be released generously by blood to tissues.

A lot of this getting fat while getting older has to do with PUFAs displacing sugar as an energy source. Due to the predominant presence of PUFAs in the diet since childhood and accumulated in the fat issues.

Poorer health will result and a long term fix is to allow the body to reset by stopping the intake of PUFAs and to allow the body to use up its PUFA stores over a natural process of releasing fats from fat cells and using it up over about 4 years. During this transition, it is unavoidable that the PUFAs will cause lipid peroxidation and the best thing we can do is to supplement with vitamin E to mitigate the effects of peroxidation. It will also help to supplement with VCO or other saturated fats so we.can increase the ratio of sat fats over PUFAs being metabolized.

Thanks, B-5 is now on my radar screen. It is one of the B vitamins that I have overlooked.

I am interested in maintaining my cognition for as long as possible. I think that the current environment is making it increasely difficult to to do just that.

@Peatslop-enjoyer said in What Vitamin B cofactors should I supplement?:

Could you provide the link? Thank you.

Vitamin B6: How much is too much? Which kind, with staples.
https://mirzoune-ciboulette.forumactif.org/t2033-english-corner-vit-b6-how-much-is-too-much#29628
Excerpt:
The English Corner – Vit B6: How much is too much?
Main ideas

Too much of a good thing is bad. Especially bad for neuro-sensitive people. Vitamin B6 is well documented for its role as a modulator of steroid hormones. No problem with food intake if not supplemented. Maximum RDA target is 25 mg B6. There are 6 vitamers and a way-out form through the urine. If we want a pharmacological effect, we have to take into account the form of the vitamers. The active form is B6 PLP. Look at the 6 vitamers form before continuing (figure):
3 basic forms of vitamers B6: PN= pyridoxine PL = pyridoxal PM = pyridoxamine

And their derivative, coupled with a phosphate molecule:

PNP = pyridoxine 5’-phosphate PLP = Pyridoxal 5’-Phosphate (active form) PMP = Pyridoxamine 5’-Phosphate

And the form used as a catabolite (excreted in the urine)

PA = 4-Pyridoxic acid.

A tight regulation of the PLP concentration is necessary in the cell: The aldehydes are toxic. A self -regulation and a protective mechanism coexist. But there is a radical side effect: PLP will no longer passes the encephalic barrier. A withdrawal effect will soon take place, with an impact on neurotransmitters.

PMP is a safer form: PMP is slightly increased in plasma, and rapidly converted into PLP and PL when needed.

An excess of pyridoxine (PN) is deleterious. No pyridoxine supplement advised: PN has an inhibition effect on PLP, the active form.

PL could be converted to PN by a PL reductase (side effects when too high supplementation).

PM could be more suitable for supplementation because of the very low formation of PN by PM.

If we suffer from a lack of enzymes, we must pay attention to the conversion pathway: PLP as a coenzyme factor has a pivotal role in catalysis of various enzymatic reactions.

See the roles of PNP-dependent enzymes, namely kinase and oxidase (+ phosphatase).
To be continued on the link. See above (my forum: Mirzoune et Ciboulette).

A tight regulation of the PLP concentration is necessary in the cell: The aldehydes are toxic.
We must not go beyond the absorption capacity of the body. We are not all equal. If you suffer from inflammation, if you need more antioxidants, you will probably burn more B6. What should be avoided is to approach the limit / the level of an overburdened of metabolism. A limit that will be different, depending on the individual.
Why does an excess of B6 or an inadequate enzymatic metabolism cause a problem of neuro-sensitivity? An excess of Pyridoxal (PLP) will lead to the inhibition of the enzyme PLK (Pyridoxal Kinase). PLK is set out of function via the “Salvage pathway” process. Details on the link, with references.
Useful link
*) English corner: B6 leads to decrease of cytokines in neuropathy
https://mirzoune-ciboulette.forumactif.org/t2041-english-corner-b6-leads-to-decrease-of-cytokines-in-neuropathy#29659
Efficacy of Vitamin B1, B6, and B12 in Peripheral Neuropathy
*) Useful nutrients in case of neuropathy
https://mirzoune-ciboulette.forumactif.org/t2031-haute-dose-de-b6-p5p-contre-algodystrophie-et-scc#29618
Mg bisglycinate, Zinc, Vit B6 PLP 20-25 mg, Vit C 500 mg, Vit D 5 000 UI (with K2).
*) English Corner: Anti-Stress & Neuro-Protective Effects of Thiamine (B1)
https://mirzoune-ciboulette.forumactif.org/t2045-english-corner-anti-stress-neuro-protective-effects-of-thiamine-b1

See part 2 (in the same post): How much and which kind of thiamine?
Excerpt from video of Dr. Allil OVERTON.
=> Practical example for beginner (patient N° 1): Basic protocol for thiamin insufficiency.
https://mirzoune-ciboulette.forumactif.org/t2045-english-corner-anti-stress-neuro-protective-effects-of-thiamine-b1#29716
With references.

@Mallard6146

As you eat smaller meals, you produce less insulin. Less insulin production means less inhibition of lipolysis, as insulin inhibits lipolysis.

Allowing lipolysis is actually a good thing, contrary to the way lipolysis is seen generally in this forum. It's because as fat stores are turned into fatty acids and metabolized, you lose weight and you lose PUFA stores.

In allowing lipolysis, you actually speed up the time for your PUFA stores to be gone from your system.

Knowing that PUFA is being metabolized and that lipid peroxidation will occur, you just have to take vitamin E during this time to keep lipid peroxidation at a minimum. The vitamin E with plenty plenty of alpha isomer, alpha tocopherol will be very helpful.

Also, supplementing from 1 to 3 tbsp of VCO will help lessen the harmful effects of PUFA being released through lipolysis.

Note that I am not advocating increasing the rate of lipolysis, but simply allowing lipolysis to occur by not letting too much insulin to get in the way by its inhibition of lipolysis. Lipolysis and the eventual oxidation of the released fatty acids from lipolysis is just part of the body's way of producing energy, as both sugar metabolism and fat metabolism are used by the body to produce energy.

However, sugar metabolism has to be predominant over fat metabolism. Fat metabolism allows the body to conserve its sugar stores for emergency situations when we are deprived of food, to keep the organs like brain fed with sugar, which the brain needs to function.

@GreekDemiGod

Unfortunately no. I think it’s a genetic issue, as my dad is similar (high T, perfect labs, but gut issues and low energy).

@LetTheRedeemed you are right about hopelessness and it is definitely manifest in my life. It's something I have to deal with on a spiritual level. I've known about Peat for about seven years but never took a deep dive into all his thought until about a year and a half ago. I think the main thing that kept me away was the pro-sugar thing, but learning more about the thyroid and how pufa disupts sugar metabolism helped me warm up to it. I have candida and sugar makes it worse, even with flowers of sulfur, so that's part of why I didn't like it, even though I always trusted natural sugar in moderation over alternative sweeteners. It was lab-tested and confirmed in 2018 but I've had candida symptoms (such as thrush) since I was around 12-13 which was '09-10. I think it was caused by stress in childhood. The thrush is not just white tongue but on areas of my body, I can use clotrimazole and betamethasone dipropionate (a steroid cream) to manage it on occasion when needed. I think my gut is likely related to my low testosterone but I haven't solved that yet either despite my best efforts with natural remedies and even some medications like fluconazole (which did nothing discernible). As for thyroid I usually take daily one cynomel and one cynoplus, crush them within the folds of some parchment paper using a mortar and pestle and put the powder in a mug to spoon out from on the tip of a teaspoon, just eyeballing it in proportion to how much I'm eating with it. Besides raw carrots / endotoxin clearers and going for walks I don't recall what else works for gut motility.

@Gaston

it won't work topically??

Effects of transdermal application of 7-oxo-DHEA on the levels of steroid hormones, gonadotropins and lipids in healthy men.
Sulcová J1, Hill M, Masek Z, Ceska R, Novácek A, Hampl R, Stárka L.
https://www.ncbi.nlm.nih.gov/pubmed/11300231

These 2 are the dumpster fire of alternative health

@OliverCloasov Garrett Smith playin the long game to restore former frens

@BioEclectic probably the same effects as those from other burnt organic matter, like burnt meat. Carcinogenic.

@AndrewPeatMatrix
Make a plan: step by step..
A carrot salad once a day IS fine (or twice if between meals).

@yerrag said in Why is raypeatforum so touchy about the topic of looks, becoming more attractive, and height?:

When you say you avoid being with narcissists, were you saying there is no judgment on your part?

I don't judge them in terms of right or wrong. I just think it's harmful for me to be near them. So I do judge whether or not it's beneficial for me to be around them.

Hope to see more agreement as we share ideas on bioenergetics

I agree, that would be nice

@Insomniac Yes, it's best to cycle on/off every few weeks and stick to the lowest effective dosage. I usually do 2-5mg maximum