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  • Scientific papers, books, blog posts. Discussion of whatever you find interesting and notable.

    714 Topics
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    chudlordC
    @jamezb46 is it not more likely that this is merely increased excretion rather than increased absorption?
  • Websites, newsletters, articles, podcasts, interviews, explainers, books, and other resources that relate to the work of Dr. Raymond Peat.

    62 Topics
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    C
    Cancer Treatments – from Research to Application MCS Foundations for Life, In memory of my dear wife Mihaela Catalina Stanciu https://www.cancertreatmentsresearch.com/ https://jeffreydachmd.com/cancer-articles/
  • Do you have a question? You can post it here, but you will only receive unqualified personal opinions and NOT medical advice in any shape or form. If something seems like medical advice but it's posted in this category, it's actually a personal opinion.

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    HarlockH
    Gm guys! I got cold urticaria when I am in contact with cold water, cold air, anything cold. Beside bad thyroid, what do you think could be the cause? Cypro works well but puts me in a really tired state that I can't afford. Thx a lot guys! [image: 1789697110092-whatsapp-image-2026-09-18-at-02.52.27.jpeg] [image: 1789697118682-whatsapp-image-2026-09-18-at-02.53.48.jpeg]
  • From medical devices to supplements. Red lights, CO2 tanks, large trash bags, kuinone, and more.

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    I was told, "Turkey tail mushroom powder is a ground dietary supplement made from the Trametes versi-color fungus, widely used to support immune function and gut health. The Japanese use this for cancer" Does anyone know anything about this? Being given to a pooch diagnosed with leukemia. Thanks
  • Recipes, food, meal prep, brands. Discuss them all here.

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    JenniferJ
    @Mossy, exactly, and for me, love is the main component—in practice, basing my choices on a love for myself (and others by extension—man being a strand in the web of life and all) and my life, not fear, has proven to be the most healing of all. I believe there is no higher vibration than God and God is love. Thank you for sharing The Four Loves with me. I found a free pdf of it on archive.org and am currently reading it. I had never read anything by C. S. Lewis before, but I was aware he was a Christian apologist so I had some idea of what to expect—I’m not Christian, myself, but having grown up in a Catholic family and attended parochial school, I’m familiar with the Christian concept of God. I think cold can have an effect on an egg’s cloudiness, too, because I’ve had cartons of eggs too close to the refrigerator’s fan that partially froze, and the half that froze and defrosted had very cloudy whites. It’s too bad you can only get the Nounós at Whole Foods. I’ve only found two stores here that carry it. If you can get your hands on Alexandre Family Farm’s whole milk yogurt and strain it, it’s similar. I used to strain the Alexandre’s, but it became too costly at $7.99 for a 24 oz container (roughly 12 oz after straining) daily. For comparison, I paid $5.99 for a 16 oz container of Nounós. No worries. I knew exactly what you meant by mushroom. I should clarify that my experience is not a reflection of the quality of lichen-based D3, but my health status, at the time. My thyroid was still recovering from the trauma of my mum’s passing and for whatever reason, when my thyroid tanks, I struggle with plants so practically everything plant-based was causing hives. I haven’t tried Haidut’s vitamin D, only because I like to take D3 orally for best absorption and don’t care for ethanol, but I appreciate that it doesn’t contain MCT, for those whose intestines would be irritated by it. Have you tried D3 in a base of olive oil? I’m wondering if you would be less sensitive to that excipient? Haha! I take no offense. As a recovering perfectionist, I understand neuroticism well and besides, you’re Italian so I trust your judgment. Now, if you try schooling me on butter, those are fighting words, mister. JK I bring my people shame—I don’t eat butter. Mayo is my dad’s condiment of choice for sandwiches and he doesn’t like the coconut-based one, due to it solidifying in the fridge and needing to take it out in advance to soften it before use, which he doesn’t have the patience for, so I figure the Graza is a good compromise. What type of olive oil do you prefer? I get my dad the “fancy” made with 100% extra virgin olive oil. Is extra virgin not good? While growing up, my mum used mainly butter in her cooking and evoo in her baking—she did cake decorating and swore by oil for moist cakes—so that’s my only reference point.
  • Discussing pistol squats, concentric exercise, resting, and other forms of strength training.

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    alfredoolivasA
    @PrinceTrebata very ho behaviour not replying. Sorry. I stopped the back ones and still don’t do them( I am still catabolic! Not getting stronger in the gym! Back aches! Bone hurts!) despite getting more than enough protein. This is perfect btw. I am not trying to be anabolic, as that usually entails with some sort of fat growth or water retention from AAS. But that’s a different story more suited for the moggy chicken Currently have been and am doing high seat biking. If I recover (hopefully when I slowly ramp up the calories), and those issues go away, I’ll throw in the stretches and stretching machine. If I find a sustainable routine with time.
  • Increasing DHT

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    @hainsloy in case you hadn’t seen, I posted some discussions about dht from “Ray Peat email exchanges” at the thread here: https://bioenergetic.forum/topic/6745/androsterone-source-in-eu
  • Metamorphosis of rpf

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    ThinPickingT
    @Living_thing said in Metamorphosis of rpf: You've not got the basics of perceive, can't think and act backwards. A shining example.
  • Homemade skincare

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    Mango butter, vitamin e, mct oil, coconut oil makes a nice body butter.
  • FDA Pushes Estrogen Therapy for Women, Requests Comment

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  • What does vit A even do

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    LucHL
    @lobotomize-me said in What does vit A even do: i havnt yet understood what it does Vitamin A exists mainly in two forms, to simplify: vitamin A = retinol. Provitamin A = carotene. Provitamin A (carotene) has its own function (for example, to protect membranes as an antioxidant), but it can also be converted into vitamin A (retinol). The conversion rate is quite low and decreases with age and context. We then speak in equivalent units. NB: 10,000 IU = 3,000 mcg Vit A. We divide the IU by 0.3 Let's simplify once more. We're only concerned with vitamin A (retinol). We mostly distinguish a role in vision, and a role in cell differentiation and growth. Not only. We talk about vitamin A1/X and the latest version is vitamin A5/X. "Vitamin A" or "retinol" are two fairly equivalent, interchangeable terms, although purists may have some nuances to add: Retinol refers to the entire molecule. As DavidPS said: https://bioenergetic.forum/topic/6850/vitamin-a5 Vitamin A5 helps activate something called the Retinoid X Receptor (RXR), which is like a central control panel or "master switch" for many important functions in the body. How does it happen (pathway)? Retinoic acid binds to the receptors RAR (retinoic acid receptor) and RXR (retinoid X receptor) before being activated into the active hormone. Note that vitamin D and vitamin A partly use the same transport pathway, particularly in their action on genes. They both act by binding to nuclear receptors that control gene expression, and these receptors require a common partner, the RXR (retinoid X receptor), to activate gene expression. It is also important to avoid taking a high dose of vitamin A without supplementing with vitamins K2 and D3. Best at maximum 5 000 UI or 1 500 mcg Vitamin A (and not without D3) to avoid interference with osteocalcin, a protein involved in bone formation. Take once a week. Not at the same meal (with fat). https://www.julienvenesson.fr/interaction-vitamine-a-vitamine-d
  • He Asked ChatGPT One Question… Then It Got Disturbingly Prophetic

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    daposeD
    I like asking those old magic 8 balls question about what to do and what not.
  • This topic is deleted!

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  • How Much Protein Do Tour de France Riders Consume?

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  • turkey neck

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    @alex155 pork neck bones are good but to me less fatty. Good in sauces.
  • Low T and Anxiety, questions about steroids

    ray peat testosterone steroids
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    lobotomizeL
    are your balls hot often or do you have a varicocele?
  • How can I heal from a sunburn?

    sunburn niacinamide aspirin redlight
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    ovenO
    @oven Be careful with aspirin once sunburned. It can be useful when taken prior to sun exposure to make you slightly less prone to burning, but afterwards hypoglycemia becomes a serious consideration. Try listening to your cravings when burnt instead of following a protocol.
  • Sugar Fasting General

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    LucHL
    @Kilgore I didn’t say to eat 5-600 K/cal. as often read in a 5.2 diet. You’ve well done to attract the attention that when starving the body you could depress the metabolism (brain and thyroid). Always listen to the body reaction and adapt if required, otherwise metabolism will slow down (spare mode). If we except people with glycemia problems, who shouldn’t follow a low-calorie diet, I said we shouldn’t eat less than 80 % of our needs, on a regular basis. Or you’ll pay it soon or later, with a lack of essential nutrients, on top of that. The problem is not to lose weight, but not to regain the lost weight and gain more on top of it as in 90% of cases. So to be clear, what I mention: a) 5 days, I advise to eat / take your usual intake. 100% Mind the breakfast / the first meal as the insulin reaction of the first meal is going to impact the rest of the day. If you eat less – no matter why – which I do not advise (no need here to lose weight), don’t eat less than 80 % of you metabolic needs (metabolism + physical expenditure). Focus then on nutrient-dense foods. b) 2 days a week (not in a row) between 1200-1600 K/cal. So usually 2 meals. Why this level and not 5-600 K/cal., as often read. Our 3 mains organs require that amount to function well (liver, hart & brain). Note: If we combine 5.2 with 16.8 – what I try when want to lose excess weight (> 23 BMI), it’s ideal to take advantage (1) NB: Most of us will have to make staples, to reload energy or to make it easier when encounting a Herxheimer reaction (detox reaction). It's also normal to stall at some point during weight loss. 2 to 3 weeks is quite common. Don't rush things, or your brain will make you pay (slow-down mode). At that moment, 8-10 days after a pause, you can exercise, but in cardio mode, not in high intensity. For instance bike, quick walk (6 – 8 Km/H) or swimming. A dynamic pace but manageable over a long distance (30 minutes). Avoid exceeding 120-140 heart rates (80% of MHR) MHR: 220 – age. For beginners, and to obtain a more accurate measurement, it is recommended to perform a supervised stress test. Sources and References The 16:8 diet, an intermittent fasting method, can potentially offer several brain-related advantages by promoting metabolic switching and autophagy, a cellular cleanup process. These mechanisms may enhance brain resistance to stress, improve cognitive function, and potentially slow down age-related cognitive decline. Counter-indication: glycemia problems and brain disturbances (emotional instability). Mark Mattson, senior investigator for the National Institute on Aging, which is part of the US National Institutes of Health (NIH), has researched the health benefits of intermittent fasting, as well as the benefits of calorie restriction. According to Mattson, there are several theories to explain why fasting works: http://fitness.mercola.com/sites/fitness/archive/2013/06/28/intermittent-fasting-health-benefits.aspx?e_cid=20130628_DNL_art_1&utm_source=dnl&utm_medium=email&utm_content=art1&utm_campaign=20130628#_edn6 Note (LucH): I don't take Dr. Mercola's advice for granted. Too biased. Not suitable for everyone. *) The Health-Promoting Effects and the Mechanism of Intermittent Fasting J Diabetes Res. 2023 doi: 10.1155/2023/4038546 Health Benefits of IF IF can trigger autophagy, a cellular process that helps remove damaged cells and promotes tissue regeneration, potentially contributing to longevity and disease prevention. Insulin sensitivity (HbA1c) Weight Loss by people with high BMI Reduced Inflammation (improving gut health and a healthy gut microbiome) Cellular Repair and Protection *) Health Benefits of Intermittent Fasting Microb Physiol 2024. https://doi.org/10.1159/000540068 There are many benefits in losing weight; boosting immunity; countering the risks of diabetes, cancer, and cardiovascular diseases; and slowing the process of ageing. IF studies in animal models suggest that the process induces longevity, improve metabolic health, and positively influences hormonal changes. IF also seems to influence inflammatory reactions, lipid metabolism, and insulin sensitivity. Other sources  CMAJ April 8, 2013 http://www.cmaj.ca/site/earlyreleases/8apr13_intermittent-fasting-the-science-of-going-without.xhtml  Prostate Cancer Prostatic Diseases 2010;13:350-5 http://www.nature.com/pcan/journal/v13/n4/full/pcan201024a.html  CMAJ March 20, 2013 http://www.cmaj.ca/content/early/2013/03/25/cmaj.109-4437  Eurekalert, Study finds routine periodic fasting is good for your health, and your heart, April 3, 2011 http://www.eurekalert.org/pub_releases/2011-04/imc-sfr033111.php  Free Radical Bio Med 2007;42:665-74 http://www.sciencedirect.com/science/article/pii/S089158490600801X  International Journal of Obesity 2011;35:714-27 http://www.nature.com/ijo/journal/v35/n5/full/ijo2010171a.html  Washington Post December 31, 2012 http://www.washingtonpost.com/national/health-science/fasting-may-protect-against-disease-some-say-it-may-even-be-good-for-the-brain/2012/12/24/6e521ee8-3588-11e2-bb9b-288a310849ee_story.html?tid=wp_ipad
  • Post nut clarity

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    lobotomizeL
    @nicemushroom17 """Ich bin mir nicht sicher, ich schaue definitiv gut in die Augen der Menschen, besonders bei Frauen, zu denen ich mich hingezogen fühle, oder ob sie ein guter Mensch sind.""" so i will recommend you try out l reuteri as it raises oxytocin similar to gazing into a partners eyes or ejaculation it. you can ferment your own dairy with it so to not need to buy it often context : l reuteuri is a bonding hormone which raises testosterone and has many benefits only downside from it is that you may become more complaint if it is paired up with high serotonin. as if you believe everyone around you loves you and you love them you may be more receptive to general requests or worse so be aware
  • why is the search function in lowtoxinforum locked behind a paywall

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    ThinPickingT
    @Hearthfire said in why is the search function in lowtoxinforum locked behind a paywall: I really do miss the Ray Peat Forum. Maybe this one could e/acc with the addition of a 'Political Talk, Alternative World Theories' category and schizoid recruitment drive.
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    lobotomizeL
    https://testonation.com/2020/06/26/the-high-acetylcholine-syndrome/
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    alex155A
    @teamfortress too many 5-ar inhibitors bro... https://pubmed.ncbi.nlm.nih.gov/11380153/ Abstract Hamster flank organ growth, as measured by an increase in the area of the pigmented macule, is androgen-dependent. When flank organs of a castrated hamster are treated topically with testosterone, the flank organ becomes larger and darker. Since this growth is known to be dependent on the intracellular active androgen, 5alpha-dihydrotestosterone (DHT), inhibitors of 5alpha-reductase which converts testosterone to DHT can inhibit the growth of the flank organ. Certain unsaturated aliphatic fatty acids, such as gamma-linolenic acid and myristoleic acid, as well as other natural compounds, including alizarin and curcumin, are 5alpha-reductase inhibitors and inhibited flank organ growth. Green tea catechins, including (-)-epicatechin-3-gallate, and (-)-epigallo-catechin-3-gallate (EGCG) are also 5alpha-reductase inhibitors and inhibited flank organ growth. However, (-)-epicatechin and (-)-epigallocatechin, which are not 5alpha-reductase inhibitors, also inhibited flank organ growth. EGCG also inhibited DHT-dependent growth of flank organs. These catechins, therefore, may act by a mechanism other than inhibition of 5alpha-reductase. The effect of EGCG and other compounds was localized at the site of application; they did not affect the growth of the contralateral flank organ in the same animal. Since these compounds do not appear to exhibit systemic effects, they may be potentially useful for treatment of androgen-dependent skin disorders.
  • The Coffeine, Serotonin and Dopamine conundrum

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    It seems that... Caffeine -> Physical work (Exercise) -> Mental work ...makes the mental work much less stressful than... Caffeine -> Mental work
  • OCD, ADD, Fatigue

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    ?
    https://youtu.be/XSUJHKAPAdg?si=hvOc2NlX7LtlHAfU I have OCD too and I really like this guys perspective on it
  • Jobs without BPAS?

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    sunsunsunS
    @alfredoolivas are you on vacation?
  • Missing small details

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    lobotomizeL
    solution was: I realized i was still doing stuff which kept my acetylcholine too high i dont remember what it was exactly but probably too high of vit b1 dosing or something else. after i stopped the diet habit which raised my acetylcholine i aced my exams