@NoeticJuice https://docs.google.com/document/d/1IeGVVmKpwlMhCijIAzZ6gHdrjFVpWdzSaloXhuEaO_I/edit?usp=sharing check this out

@yeyo12 said in Starch and Dairy problems: What the hell am I supposed to eat lol For breakfast I often eat 2 fruits and a protein (ham or 1 slice Gouda cheese). No acid in the winter period. Take one tsp coconut oil. If you need more calories, double the portions. For midday meal, begin with a soup or a salad. Soup in a thermos if you work outside. The salad has been prepared the day before. Vary the type. I take one slice or two of the preceding evening cooked meat. If you want more calories, Greek yoghurt (150 g / 6 oz.) with a banana (ripe to avoid starch) or grape + honey or coconut sugar or muscovado. I target 50 g sugar (400 Kg) with a balance between glucose and fructose. White cheese (full fat) is an option too, in order to avoid an excess of one type intestinal bacterium. Variety is a key element if you don't want to suffer from bacterial overgrowth of one kind. If still hungry, you eat one slice of home made bread or 2 slices of Wasa: two slices of wholemeal Wasa (wheat rusk with sesame seeds). With butter and jam or apple and pear syrup. Adapt to what you like and / or tolerate. But vary ! One or two fruit for a snack. + tea or coffee with a biscuit. You can also prepare a shake with useful nutrients to balance acid-base minerals (Mg K Ca + other required nutrients). For the evening meal: Alternate rice, pasta (spaghetti /simple noodles) , frozen vegetables prepared in a wok + chicken breast or roast duck or whatever you like, but vary... NB: I use hazelnut milk instead of cow milk. No rice nor almond milk (glycemia) when I eat oat: Jordan simply crunchy (oat) (or the natural kind (simple oatmeal) + 1 tsp honey), 6 half pecan nuts, 1 tbsp raisin, shredded coconut + 240 ml hazelnut milk. You can add a half apple or other seasonal red fruits (strawberries or blueberries) Adapt to your tolerance and target (for PUFA).

@16charactersitis Bro, I have familial hypercholesterolemia and 3 heart attacks... I don't know if it's safe to take thyroid hormones in this condition? (the last heart attack was in August 2024) I'm 35 years old, all the veins on my arms and legs hurt from K2 (pulling sensation) I take D3 every other day 2000, it's summer now, I'll try to stay in the sun longer

@cs3000 all “insoluble fiber” including pectin seems to be problematic. Have you seen this: https://lowtoxinforum.com/threads/soluble-fiber-causes-liver-cancer-insoluble-and-antibiotics-prevent-stop-it.26165/ ?

@16charactersitis said in starting T3: I think ray alluded to the likelihood that most have too much Iodine if I understood correctly RP has suffered from an immune reaction (acne). So he had a pre-conceived feeling. And what is found on internet is an interview by Rita Lee. She gets the information out of him (she drags it out of RP). She puts the questions and gives the answers (rhetorical questions). RP has never explained clearly why, except repeating the mainstream idea, still not developing the reason.

I think Peating changed for me from a method of "feeling OK" (vs. feeling straight up bad often) to a method of feeling great when I started including weekly beef liver slices. idealistic Read V. I. Lenin's "Materialism and Empirio-Criticism". Or just watch the Cockshott video on the same: https://www.youtube.com/watch?v=D-VQkT8TcJM Ray Peat Said: One of Lenin's best pieces of writing was explaining essentially that the concept of materialism in the West is pure idealism, absolutely the negation of materialism in Lenin's sense. Lenin said knowledge is composed of memory, but the memories are recordings of experience, and experience is always new. The source of experience is matter, and so matter is only what is potential to be experienced. So materialism means looking to the future and the possibilities of experience, where the genetics and reductionists try to base their rationalism on an organization of existing knowledge, pre-existing ideas, and breaking those down into logical, computable units and so on. The essence of Lenin's type of materialism is essentially identifying it with the life process, the process of being conscious and having new experience is the process of interacting with the material world. So this is the same idea as Aristotle's prima matter, the pure potential out of which everything arises. Yep, creative potential.

@Rah1woot yes, I agree

@gg12 I don’t know, I may have had a good effect on my morning wood when turning the Wi-Fi off in the house, but I don’t remember if this perceived effect happened on the same day i turned the wifi off.

@CrumblingCookie Those are interesting ideas for modifying tocopherol, but you'll have to do safety studies before anyone wants to inject it and those cost a lot more than $35,000

@davisjedwards theres not really an easy way to do it at home. the companies that do it have some bulk process for seperating the membrane from the shell. youre probably getting some membrane with your eggshell unless youre peeling it out. the dose is really low tho.

@alfredoolivas altereco doesn't either

@alfredoolivas I think he ordered dht raws before they went out of stock, and I get good results from his dht liquid. that's all I can say, and yes my only criticism is there is no testing as some proof that it's correct dht

@Turk That's no fun.

I stopped eating meat (I can't digest it, because of biliary pancreatitis) now I eat red lentils, a liter of yogurt with bifid bacteria, olive oil (coconut oil gives me severe colic) I also eat apples and some berries... I mean that a vegetarian diet can be useful for some

@BeefEnjoyer How are you doing now? Any better? Have you managed to solve the problem or identify the culprit of your hypersalivation? Dealing with a similiar situation over here...

I came across a claim that cancer hypoxia can be explained by the lack of sufficient carbon dioxide production, invoking the Bohr effect for this. Carbon dioxide helps in oxygen offloading from hemoglobin, but it's not an imperative factor. It would have been more appropriate to argue in terms of uncontrolled and fast growth outpacing the ability to properly vascularize the mass, leading to poor oxygenation. Cancer cells can produce substantial amounts of carbon dioxide with the aid of cytosolic carbonic anhydrases. Suppose that the external carbonic anhydrases (↓CO₂) overwhelm the internal ones (↑CO₂), to the point of depleting carbon dioxide. However, the effect of carbon dioxide on hemoglobin is primarily mediated by acidity from carbonic acid deprotonation.* Tumors will form plenty of carbonic acid and tend to have the surroundings extraordinarily acidic, so it remains possible that this acidity reaches hemoglobin, which circulates in blood rich in hydrocarbonate ions. Carbon dioxide is just one of the factors affecting the oxygen-hemoglobin association. Not surprisingly, acidity, temperature, and glycerate-2,3-bisphosphate also influence its behavior. In tumor thermography, they take advantage of overactive cancerous tissues being warmer than healthy ones. *The erythrocyte The oxygen affinity of Hb is influenced by H+ in a manner termed the Bohr effect. In capillaries of metabolizing tissues, CO2 enters RBCs where it is rapidly converted to H2CO3 by carbonic anhydrase (carbonate dehydratase). This carbonic acid spontaneously ionizes to H+ and HCO3−. The increased H+ concentration decreases the oxygen affinity of Hb and facilitates oxygen delivery to the tissues. The direct binding of CO2 to Hb in carbamino groups also lowers oxygen affinity, but this effect is considered to be minor. [image: 1746835363277-a19a58cc-80c7-4be0-b3b8-fd7de969f6ef-image.png]

@pittybitty said in What is Metabolic Uncoupling?: why is metabolic uncoupling such a sought after property in the peat-sphere? From what I've understood so far: Short version: Mitochondrial uncoupling makes reference to the use of ATP, not for energy production but for “respiration” or other biological processes (thermogenesis and defense against oxidative damage: ROS). According to RP When mitochondria are “uncoupled,” they produce more carbon dioxide than normal, and the mitochondria produce fewer free radicals. Source: Protective CO2 and aging. https://raypeat2.com/articles/articles/protective-co2-aging.shtml Full explanation (to be confirmed): Uncoupling mitochondria What is the role of uncouplers in mitochondrial function and energy production? The uncoupling proteins (UCP) are transporters, present in the mitochondrial inner membrane, that mediate a regulated discharge of the proton gradient that is generated by the respiratory chain, to serve functions such as thermogenesis, maintenance of the redox balance, or reduction in the production of reactive oxygen ... (PMC2924931) Explained differently: Mitochondrial uncoupling makes reference to the use of ATP, not only for energy production but for “respiration” or other biological processes (thermogenesis and defense against oxidative damage: ROS). Source: ScienceDirect.com (PMC151194) When we partially bypass the natural process of producing energy (through the uncoupling process), we limit the production of ROS. The attenuation of ROS by partial uncoupling while maintaining sufficient ATP production would be a potential mechanism for delaying cellular senescence (Papa and Skulachev, 1997; Brand, 2000). According to RP When mitochondria are “uncoupled,” they produce more carbon dioxide than normal, and the mitochondria produce fewer free radicals. Note (LucH): CO2 is very important when trying to lower stress induced by metabolism or other "intruders". Source: Protective CO2 and aging. https://raypeat2.com/articles/articles/protective-co2-aging.shtml Natural uncouplers FFAs form one of the major class of endogenous mitochondrial uncouplers. They can act through various mechanisms. First, they stimulate directly mitochondrial respiration, as seen in intact isolated brown adipocytes or mitochondria isolated from these cells [28,29]. Capsaicins and their derivatives are red-pepper components and are long known for their capacity to induce the upregulation of uncoupling proteins, even in vivo [62]. The molecular mechanisms are still unclear but could involve sympathetic stimulation [63,64]. T3 Thyroid hormone. Among the natural endogenous molecules with uncoupling properties, one can also cite the thyroid hormone T3. T3 regulates mitochondrial uncoupling by different mechanisms: (1) by sympathetic stimulation [61], (2) by increasing acylcarnitine production [61], thereby activating mitochondrial respiration/uncoupling, and (3) by directly stimulating the transcription of the Ucp1 gene [37]. Cellular response to uncoupling It can be easily understood that the activation or induction of mitochondrial uncoupling will lead to the activation of cellular mechanisms/responses in order to cope with induced stress and/or to regulate this process. For instance, a severe mitochondrial uncoupling can lead to rapid cellular ATP depletion and, if the stress persists, to the triggering of other cellular mechanisms, such as cell death.