@LucH said in Iodine - too much!:
Another clue: interaction between lipovitamins
=> Ratio revisited.
Excerpt
Vitamin D toxicity redefined: vitamin K and the molecular mechanism.
Vitamin A protects against vitamin D toxicity by preventing the excessive production of vitamin K-dependent proteins, especially matrix Gla protein, also known as MGP.
It may be, then, that an extreme imbalance between vitamins A and D leads to the synthesis of abnormally high amounts of MGP. If there is enough vitamin K to activate all of the MGP, it will help protect the soft tissues from calcification. If, instead, the vitamin K cannot keep up with the level of MGP being produced and the pool of vitamin K becomes depleted, soft tissue calcification ensues.
Thus, we could also say that vitamin A exerts a vitamin K-sparing effect.
Note: If our levels of vitamin D already turn round 35 ng/ml, we shouldn't take high levels of vitamin D. 1.000 UI is enough. Six months a year since my latitude is 50°, North hemisphere. (From 02 September till 01 March).
Useful info on the ratio on Masterjohn's site but I don't like the way CM's site has evolved.
Thank you for making an easily understandable explanation of the interaction between vitamin A and D and vitamin K and MGP. And the effects on soft tissue calcification.
Thank God I don't take vitamin D supplementation and rely on getting D from sunlight, though I can say that if there's anything, I might be falling on the low side of D. Lately I've been catching up on sunshine as summer approaches (after Easter), and according to the Dminder app, on my sun exposure the past 2 months my D is at 21 ng/ml. It would likely be higher, as I had not accounted for the D that I take in with food.
Neither do I take vitamin A supplementation, but I think a weekly liver intake in my diet would keep me sufficient in it, and not make me overdosed on it either. I have been on this routine for 9 years, and it has paid off well as I attribute my improved vision to this. For the first time, the requirement to wear nearsighted glasses for driving was removed in the driver's license I was issued last year. And I'm still able to maintain my ability to read type in my cellphone.
As for K, I have been eating well cooked greens for lunch and dinner for the past 8 years. Greens are not loaded with calcium and magnesium, but also vitamin K. It may not be K2, but I recall Ray recommending vitamin K, so I'm not worried not taking K2 supplementation.
As far as tissue calcification goes, I believe that my arteries are in good shape, based on monitoring my arterial stiffness index and my reflective index, using an app (Heart Rate Analyzer) running on my smartphone, a Samsung Galaxy S10 equipped with heart rate and oxygen saturation sensors.
However, my microcirculation, where capillaries are involved, can stand some improvement. It is slightly clogged up, as indicated by the RDW (rbc distribution width) in my CBC. It is at 15.5, above the high range of 13.
