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  • Scientific papers, books, blog posts. Discussion of whatever you find interesting and notable.

    627 Topics
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    U
    Increased Androgens: A pilot study on male volunteers (1 g/day for 1 month) found that DCI administration was associated with a +23.4% increase in testosterone and a +13.8% increase in dehydroepiandrosterone (DHEA). Reduced Estrogens: In the same study, DCI significantly reduced estrone levels (-85.0%) and reduced estradiol levels (-14.4%). Androgen Precursors: In addition to DHEA, other androgen precursors like epiandrosterone also increased (+39%). Aromatase Inhibition: DCI is believed to act as an aromatase down-modulator (inhibitor), reducing the conversion of androgens (like testosterone) into estrogens (like estradiol and estrone). D-chiro-inositol (DCI) acts to mimic insulin and also stimulate PDHP (pyruvate dehydrogenase phosphatase), which in turn dephosphorylates and activates PDH (pyruvate dehydrogenase). Acute Post-Meal Reduction: Clinical studies have shown that DCI, often in combination with myo-inositol, can acutely reduce the insulin spike that typically follows glucose or carb intake. Improved Sensitivity: By enhancing the activation of the insulin receptor pathway (specifically IRS2 and GLUT4), DCI allows the insulin already present in your system to work more effectively. Sparing Effect: Because DCI mimics certain insulin actions—like promoting glucose uptake into muscle and fat—it can have an insulin-sparing effect, meaning the body achieves the same blood sugar control with lower systemic insulin levels. taking D-chiro-inositol (DCI) or similar mimetics with carbohydrates can reduce the body's overall need for insulin by improving how cells process glucose.

  • Websites, newsletters, articles, podcasts, interviews, explainers, books, and other resources that relate to the work of Dr. Raymond Peat.

    62 Topics
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    C
    Cancer Treatments – from Research to Application MCS Foundations for Life, In memory of my dear wife Mihaela Catalina Stanciu https://www.cancertreatmentsresearch.com/ https://jeffreydachmd.com/cancer-articles/

  • Do you have a question? You can post it here, but you will only receive unqualified personal opinions and NOT medical advice in any shape or form. If something seems like medical advice but it's posted in this category, it's actually a personal opinion.

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    alfredoolivasA
    @engineer Drop everything

  • From medical devices to supplements. Red lights, CO2 tanks, large trash bags, kuinone, and more.

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    BioEclecticB
    I found this link: https://optimizeyourbiology.com/diy-vitamin-d-sun-lamp In this discussion thread: https://lowtoxinforum.com/threads/how-to-build-your-own-vitamin-d-lamp-testing-included.49549/ Build your own sperti lamp. Am somewhat familiar but will look further into this.

  • Recipes, food, meal prep, brands. Discuss them all here.

    233 Topics
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    sunsunsunS
    also posting here, someone on rpf posted about embryo rice, this is something I am looking into, apparently, and im not sure, it is usually brown rice , and in the package they will also put in the embryo from the processing of other rice into white rice to boost the nutrients. I might be wrong, it might also be brown rice that is only partially processed so that it removes something but retains the embryo, im not sure, it's sold at asian supermarkets and I haven't tried it yet.

  • Discussing pistol squats, concentric exercise, resting, and other forms of strength training.

    85 Topics
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    alfredoolivasA
    @sunsunsun https://www.youtube.com/watch?v=7f25pFhuAaY
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  • urbrainonsugarU

    Rapamycin: Anti-aging and metabolic dream drug?

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    DavidPSD
    Results from a human study. Influence of rapamycin on safety and healthspan metrics after one year: PEARL trial results (2025)
  • ?

    Tuna (reposted from /r/raypeat)

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    @eduardo-crispino said in Tuna (reposted from /r/raypeat): Tuna lines up planetarily with the ocean. Tuna is an octave of ocean energy. In fact, it's the energy of the center of the ocean. It's an energy school that is directly from the center of the ocean. This is an energy that is swimming on our planet right now. [image: 1744771953023-548270d2-0af5-4d47-be16-4236c95adc61-image.png] https://www.google.com/url?sa=i&url=https%3A%2F%2Ffishesofaustralia.net.au%2Fhome%2Fspecies%2F724&psig=AOvVaw0uV_tMCK0YjWPbDR7MsfqW&ust=1744858342634000&source=images&cd=vfe&opi=89978449&ved=0CBQQjRxqFwoTCJjeuP_F24wDFQAAAAAdAAAAABAJ Tuna maxing
  • PrinceTrebataP

    Help getting rid of Acne

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    R
    @PrinceTrebata In my case it was enough to stop contact with bacteria that presumably lived off of the various face oils I was depositing in that sleeping mask by being alive. I also like weekly liver a lot after I started to do that recently. Supposedly it can help with keeping the skin/other membranes in a good functional state. But this should not be overdone. Might also want to try a hairstyle that keeps hair from touching the face as much.
  • cs3000C

    RFK Jr speech on the chronic disease situation

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    J
    You guys have no tact. He can't come in guns blazing against vaccines. His whole initiative would be dead on arrival. During his hearings he emphasized he'll put aside his biases and follow the science. Long story short, he's already launched a large research effort with hundreds of scientists around he world to square away the cause of autism. If you've followed him long enough, you already know what this entails. He claims the conclusion in September will have the answers. This essentially lays the foundation for the push to alter the vaccine program how he sees fit. Critics will then be unable to brush him off using "junk science" when the science they'll have to argue against was done by their beloved CDC and other traditionally "establishment" programs around the globe. So don't throw the baby out with the bath water yet. It's a 2-4yr game we're playing.
  • S

    How high is my iron in peat world?

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    LucHL
    @Samyo I've corrected iron overload with blood take once a year. Twice advised.
  • P

    Salt!

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    P
    @DavidPS I am skeptical. Up to 30g of dietary salt intake/day has been relatively common in the US, Europe and Japan before refrigeration, due to salted fish, pickled vegetables and salty sausages all having been staples. Cancer is a modern disease that was not prevalent at that time. You linked a meta study so it's hard to pin down an exact methodology but consider the connection between salt and fast food in the modern age. A lot of the salty foods nowadays are fried in vegetable oil, meaning PUFA, meaning cancer. If you don't change what you eat, but simply add more salt to it there shouldn't be much risk. I didn't choose a specific salt target btw, I simply became more generous with adding salt to my food and the 15g is where I ended up naturally. Aside from a few mistakes while learning it has been absolutely delicious.
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    This topic is deleted!

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  • H

    Any opinions

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    LucHL
    @herenow said in Any opinions on postprandial blood glucose spikes beyond 140. Should people worry?: which has caused digestive problems. Begin to manage this problem first. enzymes to digest fat. mind the kind. See enzymedica lipogold on iherb.com. Hcl betaine if you got problem for meat digestion (bile problem). once a day. No legume. Rule of 1/5 or 5/1 (20 % of meat when eating carbs (pasta / rice / potato). Breakfast with carbs: the two same fruits until you digest well + 1 tsp coconut oil. No banana except if it's very ripe / has already black spots (glucose then).
  • H

    Google AI search results straight up lying about Ray Peat. Just outright fabrication. Unbelievable!

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    ThinPickingT
    https://gemini.google.com/ The answer to the same prompt there's much better. The UI and inference process is more comparable to Grok's. @Hearthfire said in Google AI search results straight up lying about Ray Peat. Just outright fabrication. Unbelievable!: Don't you find it strange, even with so little context given in the search term, it chose to say all the opposite things that Peat said, instead of what he actually said? I've mostly gotten correct results from that Google AI summary about everything else. Knowing how LLMs work, not particularly. What a whole human is doing when they're balancing sources and finding edges on the internet or elsewhere is remarkable. An LLM can't do that, yet.
  • S

    white sugar honey and maple syrup

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    @Samyo said in white sugar honey and maple syrup: @random https://x.com/CowsEatGrassBlg/status/1906882828216021187 ? Who Cares what people Say on X, everyone is an "expert" on X, aint saying sugar is absolutly Bad, just that it Can cause inflammation, simple. I Can give you an exemple, i was drinking milk and eating honey, i had symptoms, i stopped eating honey fully and part of the symptoms went away
  • KilgoreK

    RFK Jr. Officially Nominated for HHS Secretary.

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    ThinPickingT
    @Corngold said in RFK Jr. Officially Nominated for HHS Secretary.: No one climbing It'll be a wall jumping ninja with a strong aversion to the smell.
  • ?

    The food culture and by association the overall culture in North America is f**(ed

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    H
    @eduardo-crispino Well, interestingly, things like the anti-seed oil stuff is actually starting to go mainstream. Steak 'n Shake is switching to beef tallow. Ray Peat's influence continues to grow as mouthpieces like RFJ Jr. and Joe Rogan regurgitate ideas Peat popularized. People are starting to demand these things. We may yet see a day when McDonald's brings back beef tallow to fry their fries. In the meantime, making ice cream (and really most everything else) at home is actually quite easy, you don't even need an ice cream mixer, although it would be a good investment. There are no mix recipes online. Tastes as good if not better than a lot of store bought ice cream. And burgers? 10/10 made at home and way healthier.
  • GreekDemiGodG

    When is high LDL cholesterol not dangerous?

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    C
    @ThinPicking Thanks much thinpicking, I will give it a look when I gather free energy for such matters.
  • M

    Vitamin A deficiency kills over half-million kids each year.

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    B
    @harry5 said in Vitamin A deficiency kills over half-million kids each year.: the challenge is how to make it accessible to everyone Also tell your operator not to worry about such things anymore.
  • J

    Need help with bowel movements

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    @James bicarbonate. OJ milk eggs spinach are all relatively high in bicarbonate. If you’re already having those, i guess you could add a little baking soda in your juice or on your eggs or spinach instead of or along with table salt. Cooking with coconut oil (eg frying eggs) or adding it to grated carrots (one or two, once or twice a day) would probably also help as would adding a little olive oil or butter to your food. Adding vinegar helps and makes it tasty. Salt too. When you don’t have time, munching on a few pre cut mini carrots will do the trick. most importantly try to avoid supplements. Seems their impurities and excipients, more often than not, confound the problem. Lo dose cypro shouldn’t be a problem. Probably helps.
  • P

    Vinyl flooring and chemical leeching

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  • Hando-JinH

    Any experiences with DHT?

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    W
    this is interesting https://old.reddit.com/r/Testosterone/comments/1hs1qnq/has_anyone_tried_dht_therapy_dihydrotesterone_not/
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    This topic is deleted!

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  • mayishimaM

    Co2 Tablets

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    @cs3000 thanks.going to try it.
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    This topic is deleted!

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