@cs3000 said in Thymus health:
Looks like a big health unlock , neutrophils are big players in autoimmune problems maybe the biggest, you see them showing up causing big damage in a wide range of health issues covid cystic fibrosis ulcerative colitis heart failure etc
and theyre highly destructive with different weapons, cytokine release, then they have proteases that degrade the structure surrounding the cell (if u inhibit neutrophil proteases in arthritis they dont develop arthritis at all https://pmc.ncbi.nlm.nih.gov/articles/PMC150852/ ), and they can form wild traps where they basically gut themselves & spill out strands of dna laced with proteins to form damaging webs like some kind of arsehole spiderman in the autoimmune situation
There is a lot I don't understand about the adaptive immune system and maybe it's this lack of understanding that betrays my view in seeing autoimmunity to be largely involved with B-cells.
In this regard, autoimmunity is not so much different from being very sensitive to stimulus that the immune system wrongly regards something that is endogenous as being foreign.
I have chronic high blood pressure and it is the result of my neutrophils and macrophages of the innate immune system trying to get rid of heavy metal toxins and periodontal infections with no success, given the persistency of these insults where they don't get permanently removed or killed. It is like Groundhog Day for my immune system where they keep repeating their efforts to get rid of persistent insults that keep bouncing back. Yet I do not consider the inflammatory effects of this endless effort to be an autoimmune condition. But I blame the tenacity of heavy metals refusing to be swallowed up and excreted out, and the ability of synergistic bacteria and fungi to defend against attack by phagocyte activity by neutrophils and macrophages.
But lately I have used techniques and substances to assist my immune system to successfully get rid of the hitherto unremovable toxins and immortal infection. But I had to employ medically unorthodox techniques to achieve these.
Seems to me medical complex is guilty of spreading misinformation and disinformation to label as autoimmune, on the strength of their vaunted research which are in many cases made up stories to lead trusting souls astray.
Yet I do not wish to throw the baby with the bathwater, for a large part of the body of research is valid, and a good filter is needed to separate wheat from chaff.