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  • Scientific papers, books, blog posts. Discussion of whatever you find interesting and notable.

    627 Topics
    4k Posts
    U
    Increased Androgens: A pilot study on male volunteers (1 g/day for 1 month) found that DCI administration was associated with a +23.4% increase in testosterone and a +13.8% increase in dehydroepiandrosterone (DHEA). Reduced Estrogens: In the same study, DCI significantly reduced estrone levels (-85.0%) and reduced estradiol levels (-14.4%). Androgen Precursors: In addition to DHEA, other androgen precursors like epiandrosterone also increased (+39%). Aromatase Inhibition: DCI is believed to act as an aromatase down-modulator (inhibitor), reducing the conversion of androgens (like testosterone) into estrogens (like estradiol and estrone). D-chiro-inositol (DCI) acts to mimic insulin and also stimulate PDHP (pyruvate dehydrogenase phosphatase), which in turn dephosphorylates and activates PDH (pyruvate dehydrogenase). Acute Post-Meal Reduction: Clinical studies have shown that DCI, often in combination with myo-inositol, can acutely reduce the insulin spike that typically follows glucose or carb intake. Improved Sensitivity: By enhancing the activation of the insulin receptor pathway (specifically IRS2 and GLUT4), DCI allows the insulin already present in your system to work more effectively. Sparing Effect: Because DCI mimics certain insulin actions—like promoting glucose uptake into muscle and fat—it can have an insulin-sparing effect, meaning the body achieves the same blood sugar control with lower systemic insulin levels. taking D-chiro-inositol (DCI) or similar mimetics with carbohydrates can reduce the body's overall need for insulin by improving how cells process glucose.

  • Websites, newsletters, articles, podcasts, interviews, explainers, books, and other resources that relate to the work of Dr. Raymond Peat.

    62 Topics
    702 Posts
    C
    Cancer Treatments – from Research to Application MCS Foundations for Life, In memory of my dear wife Mihaela Catalina Stanciu https://www.cancertreatmentsresearch.com/ https://jeffreydachmd.com/cancer-articles/

  • Do you have a question? You can post it here, but you will only receive unqualified personal opinions and NOT medical advice in any shape or form. If something seems like medical advice but it's posted in this category, it's actually a personal opinion.

    1k Topics
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    alfredoolivasA
    @engineer Drop everything

  • From medical devices to supplements. Red lights, CO2 tanks, large trash bags, kuinone, and more.

    383 Topics
    4k Posts
    BioEclecticB
    I found this link: https://optimizeyourbiology.com/diy-vitamin-d-sun-lamp In this discussion thread: https://lowtoxinforum.com/threads/how-to-build-your-own-vitamin-d-lamp-testing-included.49549/ Build your own sperti lamp. Am somewhat familiar but will look further into this.

  • Recipes, food, meal prep, brands. Discuss them all here.

    233 Topics
    2k Posts
    sunsunsunS
    also posting here, someone on rpf posted about embryo rice, this is something I am looking into, apparently, and im not sure, it is usually brown rice , and in the package they will also put in the embryo from the processing of other rice into white rice to boost the nutrients. I might be wrong, it might also be brown rice that is only partially processed so that it removes something but retains the embryo, im not sure, it's sold at asian supermarkets and I haven't tried it yet.

  • Discussing pistol squats, concentric exercise, resting, and other forms of strength training.

    85 Topics
    1k Posts
    alfredoolivasA
    @sunsunsun https://www.youtube.com/watch?v=7f25pFhuAaY
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  • P

    cocoa powder before bed?

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    ofO
    @PeatPioneer When I take cocoa powder before sleep my dreams are more vivid.
  • gg12G

    Is Graphene Oxide impossible to remove from the body

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    B
    At worst. You took a novel kind of ACE inhibitor that acts for 6 months at best. RAAS and pulmonary function are intricately linked. Pulmonary disturbance is a known and temporary outcome. But for the time scale, it's unlikely that's your cause. TL;DR, don't worry about it. https://pmc.ncbi.nlm.nih.gov/articles/PMC7670268/
  • gg12G

    Mind reading algorithm - How to rid Microchips Nanotec etc?.....

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    R
    The Long 2021.
  • I

    Epitestosterone, premature balding, and "male PCOS"

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    W
    @Insr https://pubmed.ncbi.nlm.nih.gov/16462145/ licorice reduced dhea-s stinging nettles reduced cortisol too https://pmc.ncbi.nlm.nih.gov/articles/PMC8959287/
  • J

    What's a best meal (series of meals) to return into bionergeric state?

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    C
    @jet9 depends
  • A

    Can TikTok and Apple Devices Influence Our Bioenergetic Health?

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    B
    Come back @avasinclair, these are important questions.
  • ?

    Why didn't Peating™ work for Charlie of the Ray Peat Forum dot com?

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    ?
    Natto and chicken liver have the most biotin of any food I've looked up. Natto can be super-high depending on the ferment and soybean variety. A cuppa or two of some good green tea and amongst a high calorie high nutrition diet and I think that will be better than taking supplements that address some specific theory that might not even be correct. These niggas probably could eat 4-5 meals a day instead of supplement-maxxing.
  • H

    What are the best natural/non-prescription anti-fungals?

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    H
    @BioEclectic Thanks for the reply. This is actually for a family member. I'll advise to use iodine. If that doesn't work we'll try the tea tree oil and maybe some peppermint/rosemary. I also ordered some Lotramin which is supposed to be effective against it.
  • C

    Gut transit time

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    G
    @Chris2401 Aged cascara and removing a lot of starches. I’ve never found the carrot salad affective for improving bowel movements, although I make sure to have it daily.
  • GreekDemiGodG

    Immune system support post chemotherapy?

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    LucHL
    @Insr said in Immune system support post chemotherapy?: "I was seeing new patients almost weekly who developed thyroid disease after attempting high dose iodine." - from: https://www.drchristianson.com/blog/the-iodine-controversy/ I know you want to do well. Let's take the 1st source: huge amount of iodine => Too much of a good thing is bad. Transient effect. Hashimoto without selenium to protect against immune reaction. a low dosage required. => The sources I give are from medical practitioners, with a high reputation, not like the ones I saw ... *) Do you suffer from iodophobia ? https://mirzoune-ciboulette.forumactif.org/t2092-souffrez-vous-diodophobie#30093 *) Report of a discussion on Bioenergetic.com forum where I was asked to give a piece of advice. GRay asked my advice on this video from Mercola https://www.youtube.com/watch?v=R085kZw3YBQ Mercola/Strong Sista and Alan Christianson on excess Iodine Here is my answer on the forum bioenergetics.com forum https://bioenergetic.forum/topic/3795/mercola-strong-sista-and-alan-christianson-on-excess-iodine/3?_=1740594928529 In context Iodophobia was almost born with the publication of a study by Wolff-Chaikow in 1948. In short, “the thyroid protects itself against an acute excess of iodine by suppressing the metabolism of iodine. » This is a transitory effect. The simple fact of providing iodine in supra-nutritional quantities to a subject regularly increases his TSH, sometimes to double digits for a period of several months, to spontaneously return to commonly accepted norms afterwards, and this, in a perfectly spontaneous manner. Dr. Vincent Reliquet. Analysis on the link on bioenergetics.com
  • KilgoreK

    Favorite Peat Miracle story & Is potato protein really that good?

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    JenniferJ
    @Luke, how is your thyroid function? This is probably an overly simplistic explanation, but my mechanistic guess is that progesterone is anabolic, supporting the thyroid/parathyroid glands, the main glands responsible for the integrity of all connective tissues in the body, and lowering the catabolic hormones cortisol, adrenaline etc. The plumber’s thyroid may have been healthy enough for Progest-E to reverse the damage. For someone like myself who was chronically hypothyroid, Progest-E provided only temporary relief.
  • IsmailI

    HG7 protocol - anyone tried it?

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    IsmailI
    @gloryus thank you, very much appreciate the insight; yes I did find it a little odd at the length of time he’s been doing this and the results, nevertheless he does say it’s a “work in progress”, or words to that effect. Also Elwin’s blood results did seem somewhat positive from trying certain aspects of this “protocol”. Totally agree with the blood letting/cupping as being a very good way of reducing iron as well as reducing overall intake via food - surprised he didn’t mention at least the blood letting as a way to reduce one’s iron - having said that, I haven’t read the 132+ pages of comments on this “protocol”. Still trying to make sense of it all.
  • I

    Sanitizer chemicals in food

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    I
    @sushi_is_cringe It's crazy. Hope you like bleach in your bisque!
  • B

    Rosemary oil for hair growth

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    ?
    @brenn just posting here for completeness, I got word from hair protocol expert that rosemary oil tends to cause endless sheds as long as it is being applied regularly whereas peppermint oil will cause a likely initial shed that stops and regrowth is promoted with continued usage
  • ?

    what is more peaty, a supercar or a luxury RV

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    I
    The RV because you would be free to roam. But I would go for a seagoing boat, or an airplane!
  • secondkelpingS

    Have you had issues sleeping since late last year?

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    L
    Yes (8 character minimum)
  • S

    starches

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    S
    @LucH Well it appears just be coffee, not other histamine foods,
  • S

    Increasing caffeine tolerance/metabolism?

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    S
    Thanks for the responses everyone. Re-evaluating sugar seems to be helping quite a bit - and the amount that feels good seems to be in line with 5-10 grams per cup. I'm able to tolerate 2 cups again, up from 1. We'll see how high it ends up going lol. ""Symptoms to expect when you do coffee right are calmness, focus, motivation, warmth, and stable energy. Coffee done wrong leads to anxiety, shakiness, sweating, feeling wired, inability to focus, and sometimes cold extremities."" This right here seems very much correct! No shakiness or "tired-but-wired" feeling, and sleep these past few days has been a bit better, but I know new habits take a while to test. I suppose I've been progressing over the years - black coffee in my early 20s, adding some milk in my late 20s, and now I'm adding sugar I guess. Better metabolic and stress tolerance habits as I age. It's like there's some reserve of stress tolerance we build up as carefree teenagers that we slowly but surely deplete through dumb habits (black coffee, fasting, etc) and life stress as we get older. Well, never too late to get on the right track, right?
  • J

    Making progesterone at home

    hormones
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    G
    @JamesL that's just my experience. No response whatsoever from prohormones in general without smashing cortisol/serotonin down first. You can probably do this naturally just by eating above maintenance and maybe some caffeine.
  • W

    Desoxyn - meth - good or bad from a peat perspective

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    T
    @wester130 [image: 1740191192052-adderallprolactin.jpg]