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  • Scientific papers, books, blog posts. Discussion of whatever you find interesting and notable.

    627 Topics
    4k Posts
    U
    Increased Androgens: A pilot study on male volunteers (1 g/day for 1 month) found that DCI administration was associated with a +23.4% increase in testosterone and a +13.8% increase in dehydroepiandrosterone (DHEA). Reduced Estrogens: In the same study, DCI significantly reduced estrone levels (-85.0%) and reduced estradiol levels (-14.4%). Androgen Precursors: In addition to DHEA, other androgen precursors like epiandrosterone also increased (+39%). Aromatase Inhibition: DCI is believed to act as an aromatase down-modulator (inhibitor), reducing the conversion of androgens (like testosterone) into estrogens (like estradiol and estrone). D-chiro-inositol (DCI) acts to mimic insulin and also stimulate PDHP (pyruvate dehydrogenase phosphatase), which in turn dephosphorylates and activates PDH (pyruvate dehydrogenase). Acute Post-Meal Reduction: Clinical studies have shown that DCI, often in combination with myo-inositol, can acutely reduce the insulin spike that typically follows glucose or carb intake. Improved Sensitivity: By enhancing the activation of the insulin receptor pathway (specifically IRS2 and GLUT4), DCI allows the insulin already present in your system to work more effectively. Sparing Effect: Because DCI mimics certain insulin actions—like promoting glucose uptake into muscle and fat—it can have an insulin-sparing effect, meaning the body achieves the same blood sugar control with lower systemic insulin levels. taking D-chiro-inositol (DCI) or similar mimetics with carbohydrates can reduce the body's overall need for insulin by improving how cells process glucose.

  • Websites, newsletters, articles, podcasts, interviews, explainers, books, and other resources that relate to the work of Dr. Raymond Peat.

    62 Topics
    702 Posts
    C
    Cancer Treatments – from Research to Application MCS Foundations for Life, In memory of my dear wife Mihaela Catalina Stanciu https://www.cancertreatmentsresearch.com/ https://jeffreydachmd.com/cancer-articles/

  • Do you have a question? You can post it here, but you will only receive unqualified personal opinions and NOT medical advice in any shape or form. If something seems like medical advice but it's posted in this category, it's actually a personal opinion.

    1k Topics
    10k Posts
    alfredoolivasA
    @engineer Drop everything

  • From medical devices to supplements. Red lights, CO2 tanks, large trash bags, kuinone, and more.

    383 Topics
    4k Posts
    engineerE
    @Mauritio was it the pheromones or the thermogenic part that made you consider 11 keto T?

  • Recipes, food, meal prep, brands. Discuss them all here.

    233 Topics
    2k Posts
    sunsunsunS
    also posting here, someone on rpf posted about embryo rice, this is something I am looking into, apparently, and im not sure, it is usually brown rice , and in the package they will also put in the embryo from the processing of other rice into white rice to boost the nutrients. I might be wrong, it might also be brown rice that is only partially processed so that it removes something but retains the embryo, im not sure, it's sold at asian supermarkets and I haven't tried it yet.

  • Discussing pistol squats, concentric exercise, resting, and other forms of strength training.

    85 Topics
    1k Posts
    alfredoolivasA
    @sunsunsun https://www.youtube.com/watch?v=7f25pFhuAaY
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  • GreekDemiGodG

    How to restore glucose oxidation/ insulin sensitivity?

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    nicemushroom17N
    @GreekDemiGod Any update on your insulin sensitivity? I'm dealing with some insulin resistance.
  • jamezb46J

    What 20th century experiment should I replicate?

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    sozaS
    You're already off to an excellent start. Consider putting each group through physical and mental trials to demonstrate the most exacerbating effects of each diet, too.. As an ancillary study.
  • S

    Bacteria creating overgrowth of b12

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    S
    @Kat Histamine is probably what gives me the rash Orange juice, ketchup, coffee... icecream (a1 dairy)
  • K

    Thoughts on autoimmunity

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    No one has replied
  • L

    Cool outcomes with Niacinamide on Testes

    niacinamide testosterone
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    L
    @Rah1woot right I didn’t know until last year that different things absorb in different mediums.
  • R

    Hiatal hernia gastritis and duodenitis

    help
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    R
    Bump....
  • cs3000C

    Serotonin - effects on stress

    serotonin depression estrogen mood fatigue
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    498 Views
    gg12G
    @cs3000 Bro my friend from school just got on a ssri I will try to tell him one more time to not take it but oh well he is already very depressed I dnt blame him for having no other option.
  • nicemushroom17N

    Ears flushing

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    JenniferJ
    Hi @nicemushroom17, due to thyroid disease that went undiagnosed and untreated for years, I developed gallbladder disease and a severe case of SIBO and gastritis, which caused histamine reactions to most foods and since dietary, antimicrobial and vitamin interventions weren’t enough to improve my thyroid and gallbladder function, eliminate the overgrowth and heal my intestinal lining, I went on an elimination diet of gelatinous proteins (mainly scallops and gelatinous broth), easy to digest, simple sugars from fresh pressed fruit juice (mainly honeydew melon) and coconut water, and gallbladder friendly, medium chain fats from coconut, and started supplementing thyroid (NDT—WP Thyroid), then slowly reintroduced foods as my condition improved. It took a few months of optimizing my thyroid dose before the gallbladder and adrenaline attacks ceased, and it was about a year before I was tolerating most foods again so supporting my thyroid was of greatest importance. I haven’t researched finasteride, but does it have an immune suppressing effect? If so, that may be why a lot of your histamine issues went away while taking it?
  • nicemushroom17N

    MSM effects on skin and eyes.

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    DavidPSD
    @nicemushroom17 - I would not be MSM-maxxing. Listen to Dr. Peat's cautionary comments and decide for yourself. https://www.bioenergetic.life/clips/87733?t=3051&c=68
  • H

    Adrenaline/panic response to b vitamins

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    OrindereO
    @handsome-baby Don't worry because I forget about this place too. I remember hearing people say that when you take substances in general you should take note of the lowest dose in which you feel an effect in case you ever decide to try supplementing again
  • nicemushroom17N

    Hairloss from iron overload and effective ways to reduce iron?

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    nicemushroom17N
    @zorba990 That’s good to keep in mind. However, I think I actually have high iron based on the fact that I ate a high iron diet alongside a diet rich in fruit and low in calcium for several years. I’m pretty positive but not 100% if that’s what’s causing me problems though, we’ll see.
  • b1B

    Water consumption

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    LukeL
    https://player.fm/series/the-energy-balance-podcast/ep-21-drink-less-water-and-eat-more-salt-and-how-to-address-high-blood-pressure
  • A

    FAO vs Beta Oxidation

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    A
    @BroJonas Thanks. This is really helpful.
  • S

    Assumimg I have dysbiosis gut is made worse by any soluable fiber and insoluable

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    MossyM
    @Jennifer Thank you.
  • T

    All men have a fire that burns inside of them

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    onliestO
    @ThinPicking what sort of markers are you thinking of?
  • Aryan_RacistA

    Peaty Looksmaxxing?

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    BearWithMeB
    @voldtzeig said in Peaty Looksmaxxing?: And whatever you have to do to keep your hair. Keep your hair. How would you go about keeping one's hair?
  • William ShatW

    Feeling great when sleep deprived

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    No one has replied
  • S

    Why is this Healing People?

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    B
    "So why exactly the diet stops being magical for some people is a big question for another time." Yes sir.
  • MauritioM

    Whats the better low EMF setup? Laptop or Computer?

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    MauritioM
    Update: Mostly inspired by this thread I have bought an E-Ink tablet . The Boox note air 4c. I had to become a mini expert on e inks but I think I made the right decision. I've been using it for over a month and I like it so far. It's less taxing on the eyes. And most importantly it doesn't feel weirdly stimulating, ADHD-inducing like LCD displays. It doesn't stress me as much. There is still a little EMF: On the front the values go up to 0.5uT averaging 0.1-0.3 uT. You can compare these values to other ones given in this thread. On the back there is close to zero or zero measurable EMF, so if you touch it on the back you can reduce EMF exposure. I can't use if for working I think it's too small for that. Typing also takes longer. So I'm using mostly the stylus to literally write what I want to post, which is fine. I'm also using text to speech which works surprisingly well. Still if I need to be quick, I don't use my E-Ink I go for my laptop or phone. If I only read, research do little typing it's a very good device. Watching videos on it works as well and also feels less stimulating than on other devices.
  • cs3000C

    Just 1 minute of red light is effective

    red light incandescent light sun
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    LukeL
    @castle said in Just 1 minute of red light is effective: @Luke said in Just 1 minute of red light is effective: almost 20 years now (back then for acne) and I never cared about the warnings not to look into it. I didn't shine it directly into the eyes intentionally, but I also never closed or covered them. And I'm the only one in my family, including extended family (aside from one cousin) who has good eyes and never needed glasses. Could have many reasons of course, but maybe the red light was a factor. interesting. were you limiting your exposure all that time? I never did more than 15 minutes a day or so, maximum 20. But I didn't limit it deliberately, I just didn't see the benefit in using it more.