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Subcategories

  • Scientific papers, books, blog posts. Discussion of whatever you find interesting and notable.

    713 Topics
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    P
    This is very interesting, are there safe methods to lower acetelcholine if serotonin has been lowered? I've been on a previously higher dose of SSRI paxil and have worked with prescribing doctor to lower it to about half the level it was before (other drug I was on have lowered dosage of along with supplemental serotonin agonist drug) Ocd and anxiety have increased greatly while concentration has decreased. For example this post is during school after missing morning dose, whereas on higher doses locking in to concentrate was noticibly easier.
  • Websites, newsletters, articles, podcasts, interviews, explainers, books, and other resources that relate to the work of Dr. Raymond Peat.

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    CiceroC
    I noticed the reprint of Nutrition for Women says "100 short articles by Ray Peat, PHD," where the old one said "92...". What did they add to it? Also, note that From PMS to Menopause is for sale on Peat's website but not Amazon, and Peat's website doesn't have Generative Energy. Weird. I wonder if Katherine gets more of the money if you order from Peat's site. I'd imagine so.
  • Do you have a question? You can post it here, but you will only receive unqualified personal opinions and NOT medical advice in any shape or form. If something seems like medical advice but it's posted in this category, it's actually a personal opinion.

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    R
    @alfredoolivas agreed! You want to keep a steady flow of dhea and preg. Otherwise you can take it standalone assuming you're not taking an outrageous amount 10 times a day. Taking it for years, I never experienced suppression
  • From medical devices to supplements. Red lights, CO2 tanks, large trash bags, kuinone, and more.

    404 Topics
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    M
    @Corngold I do both
  • Recipes, food, meal prep, brands. Discuss them all here.

    241 Topics
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    MossyM
    @Jennifer Oops!  My typo caused the confusion.  I meant to type French toast, not French bread.   There is a common bread brand, like Nature's Own, that has a Brioche that is pretty good.  I just looked it up: Artesano.  I've seen that everywhere. That does make sense, the growing conditions for potatoes being key.  Where the soil, water, and sun provide the quality.  Interesting that baby potatoes are easier to digest.  I'll keep that in mind.  I do remember using Yukon gold for another recipe, and they are creamy.  I think I read they're less waxy than red potatoes, but not as starchy are russet.  I'm wondering now, if the red are too waxy, and the gold would be better, for the potato salad.  I may try them next. Wow, that dairy farm sounds like the best of both worlds: modern and traditional.  And how nice of him (to say the least) to tailor the cow's diet to address your need.  I've never heard of Louis Kervran, I'll have to look him up when I get a chance.  I've never heard of biological transmutation either.  I've lightly touched upon the subject of transmutation, in other reading, but not in the subject of health.  I remember you, and others, mentioning Brix before, which is another subject for my list. No problem, on the Vital Farms tip.  It sounds like you have the knowledge, and access, to get the best eggs where you live, let alone anything else you need.  You must keep up on all of it, with you and your dad's health needs.  I've slacked off a bit, once my health took an up turn, and my budget a down turn.  At least the timing wasn't too bad.  I would imagine the quality of food, and how animals are treated, goes hand in hand.  And I know that more care equals more cost.  Do you buy those eggs locally or are they available in stores? Yes, I was pretty shocked that I can eat bananas again.  I don't recall If I had any issues from cooked bananas, but I could guess I did.  Everything gave me trouble.  I could hardly eat anything during that time.  Ray's advice makes sense, cooking the raw starch.  And needing them to be overripe raw, as well.  Just like with plantains.  I used to love cooked plantains.  They're not native to my diet or cultural heritage, but I adopted them and ate them for a long period.  I have not had them in many years, though.  Years back I hypothesized that my heavy plantain habit may have contributed to my poor health, with all the starch, but I could guess stress caused the poor health and the plantains were proof of the poor state.  I think when you're healthy, you can basically eat like a goat.  I completely relate on the need to simplify meals.  I'm doing that everywhere I can now. That's a lot of potatoes.  You must've gotten creative eating that much.  Yes, we are more than just our bodies, though it's easy to focus the fixing of our defective systems on the mechanical, because it's the most evident and immediate.  No doubt, sometimes a mechanical fix is what's needed, and brings some relief.  I'm glad you've turned some of your focus beyond the physical.  A fit mind and spirit, I feel, is the most important.  Like the body, it has to be worked at and honed.  Which is what it sounds like your repetitive hikes, a change of perspective, helped you with. That is quite the epiphany.  I like the Biblical analogies.  I think it was King David, and some other writers in the Bible, who dealt with severe depression and burdens, who contemplated nature just as you've explained, recognizing the trees and mountains that stood before them were made by the same Creator who made their very body.  There really is relief in that.  I hope you continue to find relief and hope in that.  I feel we are brought to the end of ourselves, through our hardships, so that we might know Who made us, and that we might know our true self.  I find it interesting that you come back to your water analogy, where the idea of free flowing water gives you relief.  You're not the only one.  One of my favorite authors, C. S. Lewis, had a big draw to water, and found relief both in the idea of it, and in literally floating in it. You have the right perspective, about simply being thankful.  I know it's hard for me sometimes to maintain that under the burdens.  But whenever I get my wits about me, I do come back to that.
  • Discussing pistol squats, concentric exercise, resting, and other forms of strength training.

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    C
    I thought aspirin and/or baking soda w water is good for afterwards? Gummy bears or fruit before and during lifting, no?
  • What is Metabolic Uncoupling?

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    LucHL
    @pittybitty said in What is Metabolic Uncoupling?: why is metabolic uncoupling such a sought after property in the peat-sphere? From what I've understood so far: Short version: Mitochondrial uncoupling makes reference to the use of ATP, not for energy production but for “respiration” or other biological processes (thermogenesis and defense against oxidative damage: ROS). According to RP When mitochondria are “uncoupled,” they produce more carbon dioxide than normal, and the mitochondria produce fewer free radicals. Source: Protective CO2 and aging. https://raypeat2.com/articles/articles/protective-co2-aging.shtml Full explanation (to be confirmed): Uncoupling mitochondria What is the role of uncouplers in mitochondrial function and energy production? The uncoupling proteins (UCP) are transporters, present in the mitochondrial inner membrane, that mediate a regulated discharge of the proton gradient that is generated by the respiratory chain, to serve functions such as thermogenesis, maintenance of the redox balance, or reduction in the production of reactive oxygen ... (PMC2924931) Explained differently: Mitochondrial uncoupling makes reference to the use of ATP, not only for energy production but for “respiration” or other biological processes (thermogenesis and defense against oxidative damage: ROS). Source: ScienceDirect.com (PMC151194) When we partially bypass the natural process of producing energy (through the uncoupling process), we limit the production of ROS. The attenuation of ROS by partial uncoupling while maintaining sufficient ATP production would be a potential mechanism for delaying cellular senescence (Papa and Skulachev, 1997; Brand, 2000). According to RP When mitochondria are “uncoupled,” they produce more carbon dioxide than normal, and the mitochondria produce fewer free radicals. Note (LucH): CO2 is very important when trying to lower stress induced by metabolism or other "intruders". Source: Protective CO2 and aging. https://raypeat2.com/articles/articles/protective-co2-aging.shtml Natural uncouplers FFAs form one of the major class of endogenous mitochondrial uncouplers. They can act through various mechanisms. First, they stimulate directly mitochondrial respiration, as seen in intact isolated brown adipocytes or mitochondria isolated from these cells [28,29]. Capsaicins and their derivatives are red-pepper components and are long known for their capacity to induce the upregulation of uncoupling proteins, even in vivo [62]. The molecular mechanisms are still unclear but could involve sympathetic stimulation [63,64]. T3 Thyroid hormone. Among the natural endogenous molecules with uncoupling properties, one can also cite the thyroid hormone T3. T3 regulates mitochondrial uncoupling by different mechanisms: (1) by sympathetic stimulation [61], (2) by increasing acylcarnitine production [61], thereby activating mitochondrial respiration/uncoupling, and (3) by directly stimulating the transcription of the Ucp1 gene [37]. Cellular response to uncoupling It can be easily understood that the activation or induction of mitochondrial uncoupling will lead to the activation of cellular mechanisms/responses in order to cope with induced stress and/or to regulate this process. For instance, a severe mitochondrial uncoupling can lead to rapid cellular ATP depletion and, if the stress persists, to the triggering of other cellular mechanisms, such as cell death.
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    @CarbCarbCarbs I got fat as shit on all the peaty stuff like niacinamide aspirin and especially cyproheptadine. and the ice cream. oh, the ice cream...
  • Peat did not believe in the androgenic man?

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    KilgoreK
    @ThinPicking "I almost got the trans surgery. But my father wouldnt pay for it."
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    Apart from supplements, have you tried including well-tolerated green leafy vegetables, like asparagus or kale? It is often overlooked in the peat-sphere, but can be very helpful. Asparagus for example lowers excess ammonia, which often is a culprit for fatigue.
  • MRNA Vaccine Shedding - Legit?

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    daposeD
    @ThinPicking ha!!!
  • high carb zero added fat zero added protein for weight loss

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    LucHL
    The hardest part isn't losing weight, but keeping it off. Not to mention the fact that if you're a frequent yo-yo dieter, it will become increasingly difficult to lose the weight you regain as you get older. And you run the risk of your brain slowing down its metabolism (starvation protection mode). Not a good idea to get lower than 80 % of your required calorie intake. Otherwise, you will pay the bill early or late (deferred problems).
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  • Is it peaty to hang out in graveyards (during the day)?

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    @ThinPicking mayhaps….
  • how would you reduce DHEA-S

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  • Tell me your opinion on the covid vaxx

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    @ThinPicking somewhat but we are captive now. Animals don't breed in captivity. Isn't female birth rising too? Percent born male is decreasing. Their captivity was different for the last century. It's insane how powerful national policies and actions are for 99% of people.
  • These flapjack bars - oats and coconut oil

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    @Mossy something that is quick and easy, for people on the go yer, you could just make your own
  • Please identify the pill/tablet on the right

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    @lobotomize-me Yes, Thanks! The exact same tablet was also at the second link you gave: https://www.google.com/search?client=ms-android-samsung-ss&sca_esv=1e618ffcd8ec6d84&sxsrf=AHTn8zp7hQrynWmaupiNYpjUJXutr6k0vA:1745878225109&q=Amlodipine+besylate+2.5+mg+tablet+(generic+Norvasc)&udm=2&fbs=ABzOT_CWdhQLP1FcmU5B0fn3xuWpA-dk4wpBWOGsoR7DG5zJBpcx8kZB4NRoUjdgt8WwoMt2eLfGlVE3GaT9s2o0rEuuXaa3Xp90ImSjm6VOFeSjw-sbWSvWYDydvJUeUSyzm0b6K_cTyRTVbVi-Rni6RSXVeuPqJ359V6mTxYk1TgWI-l1rlNHzv67OJ3dDgDhdZ37G7mjB&sa=X&ved=2ahUKEwiX57ab3_uMAxUjQ_EDHXVNDtkQtKgLegQIERAB&biw=360&bih=724&dpr=3#vhid=HnEE0WAjtV3O3M&vssid=mosaic&sv=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 Ca channel blocker (for high blood pressure) for human beings, cats and dogs (off-label)
  • Those brazil nuts aren't high selenium!

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    I thought eggs had good selenium
  • Best Natural Fragrances and Coloring

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    JenniferJ
    My pleasure, @periander345.
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    yeah they already do bro LOL I saw this on reddit JFLLL *Note the noaa tag [image: 1745804234293-2953d861-8b75-47a7-99f3-27025c758ec0-image.png] Some avid reddit user responds with this and u just see the fucking chemtrail on the right : [image: 1745804267449-e8063dca-8a48-4d89-bb37-d451dd81fa7d-image.png] Its some plot to try to save the earths atmosphere before its too late and kill all the useless eaters JFL bro they are really banking on mass depopulation idk how soon but soon. 1/20 will live and it may only be people of a certain race. I saw that in this show called utopia which is literal predictive programming. The plot of the show is that there is a fake deadly virus going around and so they create a fake vax to depoopulate/sterilize. They literally have freemason symbols in the corner of a scene where the villian is revealing to the main characters that there will only be 500 million people by 2050. The powers that be make shows like that to laugh in our faces.
  • Whats the deal with low stomach acid?

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    They say taurine (seafood) glycine (eg, gelatin, Chicken wings, lamb shanks, ox tail soup) coffee (for the caffeine and the chlorogenic acid in it) coca-cola, and b1 and b7 (brewers’ yeast, orange juice..) help increase stomach acid. Better to get them from foods. Supplements would, more often than not, introduce a whole new slew of problems. Most important is to not have problematic foods, eg pufa, which hinder digestion, and focus on nutrient dense minimally adulterated foods (eg orange juice, dairy (preferably milk,) eggs..)
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    GardnerG
    Linoleic acid is probably the most potent dietary skin/scalp moisturizer due to its emollient properties and ability to strengthen the skin's barrier. I think the primary reason for receding hair line is that scalp looses moisture and slowly tightens up towards neck/temples.
  • The funniest/most charming guy i ever seen is on SSRIs

    anxeity social humor
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    lobotomizeL
    @NoeticJuice amazing stuff I was thinking about buying cistanche in the future but i habe looked up the prices in Europe and they seem to be awkwardly high I will look into it again later
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  • more finds #3

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