B1 at around 150mg a day cured me of all my digestive issues of "IBS", which I had struggled with for years, in a few days. Wasn't expecting it to do that at all, was taking it for something unrelated. I no longer need to take it daily and feel I need a "top up" of B1 every week or two. This was around 18 months ago and still have no issues.

Phytic acid in oats is anti cancer

@temple-of-salt said in Thyroid, cholesterol, muscle growth:

particularly through consumption of brain - the organ meat with the highest concentration of cholesterol

Vince Gironda's "12 to 36 raw eggs a day" protocol was based on a similar notion (along with a belief that cholesterol degrades with heat). According to him it was the closest one can get to a steroid cycle without actually using drugs. I'm not sure how much validity it has; I haven't experienced any effects from trying it, but I am hypothyroid and I haven't taken thyroid along with the eggs.

The dosage is insane. Inhibiting the breakdown of second messengers like cAMP and cGMP can have vast benefits, including sexual benefits. But you generally should not need a dose so large. 1,500-2,000 milligrams of horny goat weed is good, quality varies. Something that's 20% Icariin or higher is best. Pharma cGMP facilitators are much much more potent. I can't remember the exact equivalence, but I'm pretty sure sildenafil is like 80x more potent than Icariin. So you wouldn't need that much, like 2.5-5mgs of tadalafil would work. But I generally fail to see how this will increase "emotional closeness." This will just improve erection quality. I think peptide research like PT-141 or Oxytocin is more up the alley you're looking for. I don't think any of these substances are "Peat approved" or even generically bioenergetic friendly, so do your research thoroughly and accordingly. I do have a more nuanced approach towards nitric oxide, and I think it's obviously useful in certain scenarios. But from a sexual standpoint it's only so useful before getting diminishing returns elsewhere (like dangerous hypotension).

I see a lot of men striving to achieve that "teenage self" again. It's a valiant effort, but there's a reason few people ever succeed at this. Teenage sex drive isn't from nitric oxide or androgens. It's actually from an enhanced histaminergic tone with a lack of H3-H4 receptors. H2 (and to a slightly lesser extent H1)has a profoundly strong pro-libido effect, but in adults the autoreceptors (H3) and the H4 receptors prevent this from happening. The teenage brain still hasn't fully created all these networks yet. Dopaminergerc networks also form before serotonin. So a teenage brain is very high in pro-libido histamine receptors, dopamine receptors, and really low in anti-libido stuff like H3, H4, and serotonin.

@raytreats Awesome! I think more broadly it was stress hormones causing this, hence the spike when you drank espressos without milk or sugar. But this can have been caused by the deficiency! So not to say that isn't a perfect solution. Try to avoid additives in your supplements. Glad you solved it.

Estrogen, in sufficient quantities, just puts the breaks on testosterone production (through negative feedback loop). That's what causes feminising effects. Its not the estrogen itself that feminises. Transexuals often use anti-androgen compounds (like spironolactone) for the feminising effects. I don't think increasing estrogen to very high levels even has the capacity to fully feminise a male if his androgen are still high enough. Many men have very high estrogen but still look like men.

Progest-E

@Ray-Van-Winkle

holy shit cheapest vegan diet ever

@Norwegian-Mugabe said in How do you define richness from a bioenergetic point of view?:

@Ray-Van-Winkle Only a few select people like myself are suited for luxury.

This is incredibly real. Low frequency people given money will still live in filth and squalor, and waste their fortune on trivial distractions.

The goal is to live a charmed life. The life you save could be your own.

That's interesting, but wouldn't it make more sense to use pure topical caffeine on the scrotum for this effect? Seems like it would, because unlike coffee, the caffeine would not have to be digested first.

It's basically following the same principle of using topical t4/t3 mixtures, and NOT topical desiccated thyroid.

@basednigga2006 said in Curing Parkinson's disease with B1:

Can you not get the enough doses of b1 by eating healthy.....?

Theoretically, maybe. But we live in a real world. So in our current world: not even remotely. Stress depletes all kinds of vitamins and minerals, and our food is more devoid of them than it has ever been in the history of mankind...

Starches contain no vitamin B1. Sugar, which is what starches are converted to, requires a lot of it.

The advent of white rice (where the thiamine-rich husk is discarded) caused up to 90% of the Japanese military to become B1 deficient!!!

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@CO3 Where I live the topic is somewhat well known; for example, TV nutrition experts often promote a rule of thumb that the more liquid a dietary fat is in room temperature, the healthier it is. Confidently stating the opposite at least gets some attention, and if someone is unable to understand the solid fat/liquid oil distinction I'm not sure it's possible to simplify it even more.

@BroJonas there has to be some truth because Ray suggested if you had cortisol issues to take t3 with pregnenolone. I'm not sure how prevelant it is or how much it related to low or high cortisol.

Ray Peat email exchanges - Aspirin

@TexugoDoMel Great response, thank you!