@GreekDemiGod Unfortunately no. I think it’s a genetic issue, as my dad is similar (high T, perfect labs, but gut issues and low energy).

So good to hear!

@Mauritio was it the pheromones or the thermogenic part that made you consider 11 keto T?

Makes me feel worse afterwards, physically and spiritually.

Linoleic acid is probably the most potent dietary skin/scalp moisturizer due to its emollient properties and ability to strengthen the skin's barrier. I think the primary reason for receding hair line is that scalp looses moisture and slowly tightens up towards neck/temples.

@CrumblingCookie I wouldn't call it anti-serotonergic , the mood lift felt more like a neurosteroid boost. Which is a little different from a dopamine boost. Both are good though. Not sure about it's androgenicity , I didn't experience any detrimental effects . But I only tried it twice and I was also sick with a cold so not the best test run. I certainly would be willing to try it again if it wasn't for the constipation, but I'm sure I'll give it another go. Ive tried the old version of gonadin today with phytol in it. that was quite nice . I'm also having great results with diosgenin in the last months.

@Fructose Caffeine can dehydrate you a bit, and especially in a hot bath or something you are losing allot of electrolytes, its probably that

Results from a human study. Influence of rapamycin on safety and healthspan metrics after one year: PEARL trial results (2025)

@jimmynelson based on all this - would telmisartan be the best drug? it acts like metformin in a unique way to control insulin resistance but also helps blood pressure and reduces aldosterone

@yerrag said in Just found out I have reactive hypoglycemia. What now?: Those raccoons also feast on koi in Singapore. I don't have that problem here in our overcrowded Manila. I have a mind to move to the mountains, but when push comes to shove, I procrastinate because the idea on becoming a nomad appeals to me as well. Decisions, decisions.... I moved here from a big metropolis in 1981. I went through a bad divorce (is there any other kind?) and decided to get out of Dodge when the divorce was finalized by the Court. It was the best decision I ever made (next to that divorce). It was an amazing little town in the early 1980's. Nobody locked their doors; they kept their keys and money in their vehicles (unlocked). If a stranger needed a ride to somewhere, people were known to just hand them the keys and say, "Here, take my truck." People were so scarce in the county back then that everyone always waved when passing another vehicle on the road, acknowledging the other human being. The times have changed the place; too many tourists now. I miss my little town.

@Bling5 FYI Dairy is only nutrients. Cooked veggies can be great. yeah i saw the rat studies with how they lost fat on coca cola. show me anyone who has done that and thrived. Me. and i dont think fruit should be meals. fruit can accompany a meal and help with digestion (e.g. digestive enzymes in pineapple etc.) but it is a waste of an opportunity to make fruit a meal. again talking about body recomp an performance. not leisurely vacation diet. you would get way more out of using that opportunity to get nutrient density in. Wonderful point. The most consistent way to improve metabolism and digestion is a well balanced macro meal. Including balancing micronutrients when possible. Isolated fruit/sugar sources are fine as a snack — but I’ve found a tiny bit of protein in some form, to be handy between meals to balance high carb snacks. add cooked leaves and cabbages and bell peppers and lettuces and stuff. ive never experienced the downsides of these that people on rpf postulated about for years. in fact i did way better when i added all this stuff i took out after browsing rpf and taking ray's words too literally and personally Cooked veggies with all the tasty cofactors like a smidge of butter and cheese are great, and a great way to increase salt and gelatin intake in a palatable manner. There are methods to producing the vegetable stock in a safe manner, but for many people, including myself, something like cabbage is very powerfully anti-thyroid. For many people like myself, almost any amount of nightshades like bell peppers are terrible on digestion and brain fog. Of course I want to live my life so I trial and error where I can get away with something to make enjoyable food, but due to the anti nutrient factors, that’s very important for anyone to be aware of. If I were OP, I think it would behoove to look for recipes that remove goitrogens and phytoestrogens — be that boiling for x time and tossing the water, etc. With that said, there is no nutrient missing from a diet of weekly oysters and liver, with daily dairy and juice consumption — way cheaper, too. You may have a decent metabolism/resilient digestion, and the amounts you’re consuming aren’t impacting you. I know there are suggestions Ray makes that I don’t stick to religiously, and that’s where I’ve learned to be mindful of context (that basically means “what can I get away with lol”). https://raypeat.com/articles/articles/vegetables.shtml

No thanks Lurking.

@sunsunsun Thanks for chiming in. The dosages really are not self-evident, ever. Given the general amount of animal studies wherein astrononimcal concentrations are being used to draw conclusions, it's difficult to say what is uncalled for timidness and waste of effort and what's straight out daftly excessive, wasteful and potentiall harmful at the other end. E.g. there are still people believing they need 5000 IU hGC per week when actually 250 IU (400IU max) every other day is pretty much enough for the whole effect. Also, IFN-y is only being used at 100mcg. Its precursor Interleukin-12 (IL-12) appears to must be used only in single digit mcg amounts, if at all. Have you gained any experiences with the thymic peptides? I'll restart with the Glu-Trp thymogen and begin with the TA1.

@CrumblingCookie I've done it today again and half an hour later noticed a face lift effect also my mood seems to be better. I kept forgetting about it but I'll try to do it more often.

Found another trick for getting any AI to reply in a bioenergetic context. This one is without too much side effects, except for a skew to use expert/scientific language. Just add this to the system prompt: "Sources: Bioenergetics – Albert L. Lehninger, 1965 The Principles of Bioenergetics – Vladimir P. Skulachev, 2012 The Spark of Life: Electricity in the Human Body – Frances Ashcroft, 2012 Mitochondria and the Future of Medicine – Lee Know, 2018 Bioenergetic Medicine – Michael G. Anderton, 2000 Cellular Energy Metabolism and Its Regulation – Gerard Meurant (Ed.), 1997 Oxidative Metabolism of Mitochondria – Vladimir P. Skulachev, 1977 Molecular Biology of the Cell – Bruce Alberts et al., 1983 Mitochondria: The Dynamic Organelle – Kwang W. Jeon (Ed.), 2004 The Warburg Effect: How Does it Benefit Cancer Cells? – José M. Martínez-Reyes and Navdeep S. Chandel, 2021 The Prime Cause and Prevention of Cancer – Otto Warburg, 1966 Serotonin: The Mediator That Spans Evolution – Gernot Riedel, 2004 Thyroid Hormone and Mitochondria – Enrique Silva and José R. Bianco, 2008 The Metabolic Theory of Ecology – James H. Brown et al., 2004 Nutrition and Physical Degeneration – Weston A. Price, 1939 Stress: The Theory of Hans Selye – Hans Selye, 1956 Estrogens in the Brain – Jacques Balthazart and Gregory Ball, 2012 The Influence of Oestrogens on Mitochondrial Function – Margaret M. McCarthy, 2008 The Thyroid and the Environment – Broda O. Barnes, 1976 Ray Peat Articles – Ray Peat, 1970s–2020s (various titles and dates) Bioenergetics and Thermodynamics – Donald Haynie, 2001"

@dht I agree that keeping the steroid cascade going in important, even critical. If you HPTA is shut down, then even if you are using exogenous androgens, if you aren’t producing p5 and p4 then you aren’t getting any of the benefits that they or their metabolites turn into. My idea was to use a non-aromatizing compound like masteron or proviron and tbol or whatever else fits the bill with the idea being that your HPTA stays in tact, thus you never lose testicular steroidogenesis completely, thus you still get the youth hormones. If you were going to use progesterone for this purpose, would you try to inject it or go with oral in tocopherols? And even if you’re right about progesterone not shutting down HPTA, what do you think about the possibility that it will have anti-androgenic effects at the transcriptional level or even cause lack of libido because of how it affects the male brain?

@TheRealPeater @TheRealPeater said in I have been banned on the RPF for posting this study on Vitamin A...: @Mauritio This is a shame. I enjoyed my conversations with you and @Jam on the iodine threads. I think I'm OK posting in both places as I'm happy to give a generalised Low A approach a go...no different to how I gave SSKI a go... I'm not looking for a Great Wise Old Sage to shape my life, but I am happy to run with thoughts that interest me. I think thats totally fine. Many people have reported feeling better on a low A diet, although Im not sure how much of that is due to the absence of vitamin A and not the absence of all kinds of other things. I think its good that people get a feeling for how certains vitamins affect them. As Vitamin A can be anti-thyroid in higher doses, which is not a controversial opinion at all, just as this is not news, but has been said by Peat for decades.

@sunsunsun do you think the idea would work? I am not 100% on the idea but it seems easier than buying the powder

I notice an intense rise in estrogen within hours of consuming a seed-oil rich meal. Recently (this is a little TMI) I was on my period, which is usually light and painless. I had a big chicken kebab wrap, I could see it was dripping with pufas. That night I woke up to hot flushes, cramps and I bled through everything. This lasted for days after. So not worth it.

@Corngold I can hardly fault the author if I were to treat him like myself when I started my journey into knowing Peat. To fully grasp his ideas, one simply cannot treat it like a book report you rush thru a weekend of research. Ray doesn't have a Reader's Digest version, and I doubt anyone can write one either if a prerequisite to writing one involves reading and understanding everything he has written like one would do in going through a 7yr pHD program. But no such program exists.